Material Safety Data Sheet (MSDS) for Caprylhydroxamic Acid

Identification

Product Name: Caprylhydroxamic Acid
CAS Number: 7377-03-9
Molecular Formula: C8H17NO2
Molecular Weight: 159.23 g/mol
Synonyms: Octanohydroxamic Acid
Intended Use: Cosmetic preservative, industrial antifungal agent
Manufacturer: Please refer to supplier or packaging for contact details
Emergency Contact: Refer to country-specific poison center or emergency response provider

Hazard Identification

GHS Classification: Skin sensitizer, Eye irritant, Acute oral toxicity
Hazard Pictograms: Exclamation mark (GHS07)
Signal Word: Warning
Hazard Statements: Causes skin irritation, Causes serious eye irritation, May cause allergic skin reaction, Harmful if swallowed
Precautionary Statements: Avoid breathing dust or spray, Wear protective gloves and eye protection, Wash hands thoroughly after handling, In case of inadequate ventilation wear respiratory protection
Pictogram Codes: GHS07

Composition / Information on Ingredients

Chemical Name: Caprylhydroxamic Acid
CAS#: 7377-03-9
Concentration: ≥98% by weight
Impurities: May contain minor organic by-products, less than 2% total impurities
Other Ingredients: No hazardous ingredients present above cut-off values regulated by GHS

First Aid Measures

Inhalation: Move to fresh air, seek medical attention if symptoms develop (coughing, difficulty breathing, throat irritation)
Skin Contact: Wash with soap and water for at least 15 minutes, remove contaminated clothing, consult physician in case of irritation
Eye Contact: Rinse immediately with plenty of water for 15 minutes, keep eyelids apart, contact ophthalmologist if discomfort persists
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice, provide information on product to healthcare personnel
Most Important Symptoms: Allergic reactions, redness, itching, eye watering, gastrointestinal upset if swallowed
Notes to Physician: Treat symptomatically, monitor for delayed allergic reactions, ensure airway support as needed

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, alcohol-resistant foam, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet
Specific Hazards: Emits toxic fumes such as nitrogen oxides and carbon oxides under fire conditions
Protective Equipment: Self-contained breathing apparatus and full protective gear
Advice for Firefighters: Use water spray to cool containers, avoid inhalation of smoke, evacuate area if necessary
Combustion Products: Nitrogen oxides, carbon monoxide, carbon dioxide

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves, protective clothing, goggles, and suitable mask
Environmental Precautions: Prevent contamination of soil, drains, water bodies, contain spillage using absorbent materials
Cleanup Procedures: Sweep up and place in a suitable, labeled container for disposal, ventilate area, wash contaminated surfaces with soap and water
Spill Response: Avoid generating dust, minimize release using damp methods, package waste securely for regulated disposal

Handling and Storage

Handling: Use only in well-ventilated areas, avoid contact with skin and eyes, do not breathe dust, wear appropriate personal protective equipment
Storage: Store in tightly sealed containers, in a cool, dry place away from direct sunlight, incompatible materials (oxidizing agents, strong acids/bases), maintain at room temperature between 15–25°C
Incompatibilities: Strong oxidants, strong acids and bases, strong reducing agents
Safe Transfer: Use grounded equipment, minimize spills and dust formation

Exposure Controls and Personal Protection

Engineering Controls: Provide adequate exhaust ventilation, localized extraction preferred
Respiratory Protection: NIOSH-approved dust mask or respirator for bulk handling
Eye Protection: Safety glasses with side shields or chemical goggles
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), long sleeves, lab coat
Hygiene Measures: Wash hands after use, remove contaminated clothing immediately, do not eat, drink or smoke in handling area
Exposure Limits: No occupational exposure limits established for Caprylhydroxamic Acid; use general dust limits as guideline (e.g., OSHA PEL for particulates)

Physical and Chemical Properties

Appearance: Off-white to pale yellow crystalline powder
Odor: Slight, characteristic
pH: Not applicable (solid), solutions usually neutral to slightly acidic
Melting Point: 75–80°C
Boiling Point: Not available (decomposes before boiling)
Flash Point: Not readily flammable
Solubility: Soluble in ethanol, propylene glycol, slightly soluble in water
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.02 g/cm³
Partition Coefficient (log Kow): Estimated 2 to 4
Decomposition Temperature: >150°C (releases toxic gases on thermal decomposition)
Viscosity: Not applicable (solid form)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with strong oxidizers, acids, and bases
Hazardous Reactions: No dangerous reaction known under normal use, may hydrolyze in strong acid/alkaline media
Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide; toxic fumes upon combustion
Incompatible Materials: Strong oxidants, strong acids, strong bases
Conditions to Avoid: Excessive heat, contact with incompatible materials, open flame

Toxicological Information

Acute Toxicity: Oral LD50 (rat) estimated at 100–600 mg/kg
Inhalation: Dust may cause respiratory irritation, coughing, sneezing
Dermal: Prolonged exposure can cause irritation, possible allergic contact dermatitis
Ocular: Causes significant eye irritation, watering, redness, stinging
Chronic Toxicity: Repeated skin exposure can lead to sensitization, asthmatic symptoms reported in rare cases
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, ACGIH, or OSHA
Mutagenicity: Limited evidence; in vitro studies show no significant genotoxic potential
Reproductive Toxicity: No evidence from available studies
Symptoms of Exposure: Burning, redness, itching, nausea, gastrointestinal upset

Ecological Information

Ecotoxicity: Toxic to aquatic organisms (fish, daphnia, algae); precaution required for environmental releases
Persistence and Degradability: Moderately biodegradable under aerobic conditions
Bioaccumulation: Low to moderate potential based on molecular structure
Mobility in Soil: May absorb to soil particles, mobility considered low
Other Adverse Effects: Can disrupt aquatic microbial balance, avoid direct discharge to surface waters

Disposal Considerations

Waste Disposal Methods: Dispose of as hazardous chemical waste according to local, regional, and national regulations
Contaminated Packaging: Rinse containers thoroughly prior to disposal, use approved waste handlers
Sewage Disposal: Avoid discharge into sewer systems or natural water bodies
Reuse/Recycling: Not recommended for reused due to contamination risk
Special Precautions: Avoid creation of dust; mark waste containers clearly, prevent access by unauthorized persons

Transport Information

UN Number: Not classified as dangerous goods for transport in most jurisdictions
UN Proper Shipping Name: Not regulated
Transport Hazard Class: None
Packing Group: None
Marine Pollutant: Not classified as a marine pollutant
Special Transport Precautions: Protect from moisture and physical damage during transit, ensure external packaging remains sealed

Regulatory Information

US Federal Regulations: Listed in TSCA inventory, not subject to reporting requirements of SARA Title III Sections 302/311/312/313
EU Regulations: Registered under REACH; not classified as SVHC (Substance of Very High Concern)
California Proposition 65: Not listed
WHMIS Classification (Canada): D2B: Toxic Material Causing Other Toxic Effects
Other Country-Specific Regulations: Refer to local authorities; comply with all applicable requirements
Label Requirements: Chemical name, hazard statements, precautionary measures, manufacturer/supplier information