Product Name: Calcium L-5-Methyltetrahydrofolate
Chemical Name: Calcium salt of L-5-methyltetrahydrofolic acid
Synonyms: Calcium L-methylfolate, L-methylfolate calcium
Recommended Use: Dietary supplement, pharmaceutical ingredient
Manufacturer: Refer to supplier documentation for contact details
Emergency Contact: Seek local emergency response guidance; consult medical professionals in case of severe exposure
GHS Classification: Substance is not classified as hazardous under GHS criteria
Principal Hazards: Dust may cause mild irritation to respiratory tract, eyes, or skin
Pictogram: Not required for this substance
Signal Word: None
Hazard Statements: May cause minor irritation upon direct contact
Precautionary Statements: Avoid creating or breathing dust; wash exposed skin after handling; keep away from food and beverages; seek medical attention if adverse effects occur
Chemical Name: Calcium L-5-methyltetrahydrofolate
CAS Number: 151533-22-1
Formula: C20H23CaN7O6
Concentration: Pure substance (≥98%)
Impurities: Trace manufacturing byproducts as allowed by manufacturing standards for food grade or pharmaceutical uses
General Advice: Remove victim from exposure; seek fresh air; get medical attention if symptoms develop or persist
Eye Contact: Rinse thoroughly with plenty of running water for several minutes; remove contact lenses if present; consult physician if irritation persists
Skin Contact: Wash off immediately with soap and water; remove contaminated clothing; seek medical attention if irritation lasts
Inhalation: Move affected person to fresh air; provide artificial respiration if breathing is difficult; consult a healthcare professional if symptoms continue
Ingestion: Rinse mouth thoroughly; seek medical advice if large quantity is swallowed or if discomfort develops
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or appropriate foam
Special Hazards: Product may emit toxic fumes of carbon oxides and nitrogen oxides under fire conditions
Protective Equipment: Firefighters should wear approved self-contained breathing apparatus and full protective gear
Advice for Firefighters: Use water mist to cool containers; avoid inhaling combustion products; prevent fire runoff from entering water systems
Personal Precautions: Wear protective clothing, gloves, eye protection, and suitable respiratory protection where dust formation occurs
Environmental Precautions: Avoid release to environment; control spills to prevent entry into drains, sewers, or waterways
Methods for Cleaning Up: Sweep up and collect spilled material in appropriate containers; minimize dust formation; ventilate area and wash site after removal with water and mild detergent
Handling: Use in well-ventilated area; minimize dust generation; avoid breathing dust or consuming food and drink near substance
Exposure Prevention: Wear standard PPE such as gloves, goggles, lab coat; wash thoroughly after handling
Storage: Keep container tightly closed in a cool, dry place; store away from incompatible substances like strong oxidizers; preserve product from light, moisture, and extreme temperatures
Control Parameters: No specified occupational exposure limits established for this compound
Engineering Controls: Use local exhaust ventilation or process enclosures to minimize dust exposure; ensure eyewash stations and safety showers are easily accessible
Personal Protection: Protective gloves (nitrile recommended), safety goggles, lab coat or suitable work clothing; dust mask or respirator if airborne dust exceeds manageable levels
Appearance: White to pale yellow powder
Odor: Not significant or characteristic
pH: Neutral to slightly acidic in aqueous solution
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Sparingly soluble in water; slightly soluble in methanol; practically insoluble in organic solvents
Vapor Pressure: Not applicable
Partition Coefficient: No data available
Auto-ignition Temperature: No data available
Explosive Properties: Dust explosion possible if dispersed in air in sufficient concentration and in presence of ignition source
Stability: Stable under standard storage and handling conditions
Conditions to Avoid: Exposure to moisture, heat, and direct sunlight
Incompatible Materials: Avoid contact with strong oxidizing agents, acids, and bases
Hazardous Decomposition Products: May yield carbon oxides, nitrogen oxides, and calcium oxide under thermal decomposition
Polymerization: Not expected under normal conditions
Acute Toxicity: Low acute toxicity by oral, dermal, or inhalation exposure
Skin/Eye Irritation: May cause mild transient irritation
Sensitization: No documented evidence of sensitization by contact
Chronic Toxicity: No data indicating carcinogenic, mutagenic, or reproductive effects
Additional Data: No documented cases of toxicity at occupational exposure levels; nutritional role as L-methylfolate form
Aquatic Toxicity: No data indicating acute toxicity to aquatic life at predicted use concentrations
Persistence and Degradability: Expected to be biodegradable under environmental conditions
Bioaccumulation: Unlikely based on physicochemical properties
Mobility in Soil: Limited due to low solubility; expected to partition to soil and sediment
Other Adverse Effects: Avoid uncontrolled release; large spills could impact nutrient balance in localized environments
Waste Treatment Methods: Dispose according to local, regional, and national regulations for non-hazardous organic chemical waste
Unused Product: Consider recycling if available and permitted; otherwise, transfer to licensed chemical disposal service
Contaminated Packaging: Clean with water and detergent before recycling or disposing as non-hazardous waste
Precautions: Prevent release to the environment; do not mix with other waste streams without compatibility assessment
UN Number: Not regulated as dangerous good
Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not a marine pollutant
Special Precautions: Protect packages from damage and moisture during transport; ensure closure remains intact
Inventory Status: Listed or permitted for use in major chemical inventories for pharmaceuticals and dietary supplements
Labelling Requirements: Not subject to hazard labelling under GHS or relevant US/EU legislation
Workplace Regulations: Follow occupational health and safety regulations for chemical handling
Other Regulation: Subject to food, nutrition, and pharmaceutical product regulations according to intended use and jurisdiction
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