Material Safety Data Sheet: Calcium Gluconate Anhydrous

Identification

Product Name: Calcium Gluconate Anhydrous
Chemical Name: Gluconic acid, calcium salt, anhydrous
CAS Number: 299-28-5
Molecular Formula: C12H22CaO14
Synonyms: Calcium D-gluconate
Recommended Use: Pharmaceutical, food additive, laboratory chemical
Manufacturer Contact: Emergency phone and address information should be accessed via local supplier or safety coordinator.

Hazard Identification

GHS Classification: Not classified as hazardous under GHS
Signal Word: None
Hazard Statements: No known significant effects or critical hazards
Precautionary Statements: Avoid unnecessary contact, avoid inhalation of dust
Physical Hazards: Fine powder can form combustible dust clouds
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: May cause mild respiratory, skin, or eye irritation for some people

Composition / Information on Ingredients

Component: Calcium Gluconate Anhydrous
Concentration: ≥99%
Impurities: Water (trace), other organic/inorganic compounds (≤1%)
Chemical Structure: C12H22CaO14

First Aid Measures

Inhalation: Move affected person to fresh air, keep warm and at rest
Skin Contact: Brush off loose material, wash skin with soap and water
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes
Ingestion: Rinse mouth with water, seek medical attention if discomfort occurs
Advice for Medical Responders: Symptomatic treatment, no specific antidote

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry powder, foam, or carbon dioxide
Unsuitable Extinguishing Media: Direct water jets may spread dust
Specific Hazards: Combustible dust, can form explosive mixtures in air
Hazardous Combustion Products: Carbon oxides, calcium oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Firefighting Instructions: Contain contaminated firefighting water, cool containers with water spray

Accidental Release Measures

Personal Precautions: Evacuate area if dust forms, avoid breathing dust, use protective equipment
Environmental Precautions: Prevent further leakage if safe, avoid runoff into drains and waterways
Spill Cleanup Methods: Sweep or vacuum up without raising dust, place in suitable closed containers
After Cleanup: Wash area thoroughly with water, ventilate space if dust formed

Handling and Storage

Precautions for Handling: Avoid creating dust, avoid contact with eyes and skin, use under local exhaust
Safe Storage Conditions: Store in tightly closed containers, in a cool, dry, well-ventilated area
Incompatible Materials: Strong oxidizers, strong acids
Storage Temperature: Ambient, avoid moisture
Hygiene Practices: Do not eat or drink during use, wash hands after handling

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits specific to calcium gluconate anhydrous
Engineering Controls: Use local exhaust ventilation, process enclosures
Respiratory Protection: Dust mask or respirator (P2 or N95), especially during dust production
Eye Protection: Safety goggles or glasses
Skin Protection: Gloves recommended, lab coat or coveralls
General Controls: Facilities for eye wash and safety shower should be available nearby

Physical and Chemical Properties

Appearance: White to off-white odorless powder
Odor: Odorless
pH: 6.5 – 7.5 (10% solution in water)
Melting Point: Decomposes above 120°C
Boiling Point: Not applicable
Flash Point: Not applicable
Vapor Pressure: Negligible
Solubility: Soluble in water, insoluble in ethanol
Density: ~1.7 g/cm³
Particle Size: Fine powder or granules

Stability and Reactivity

Chemical Stability: Stable under recommended conditions
Hazardous Decomposition Products: Carbon oxides, calcium oxide on thermal decomposition
Conditions to Avoid: Moisture, excessive heat, ignition sources for dust
Incompatible Materials: Strong acids and oxidizers
Polymerization: Will not occur
Reactivity: Minimal under normal use

Toxicological Information

Routes of Entry: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Low toxicity; oral LD50 (rat) > 5000 mg/kg
Potential Effects: Mild irritation to eyes or respiratory tract in sensitive users
Chronic Effects: None known from normal occupational exposure
Carcinogenicity: Not listed as carcinogenic
Mutagenicity: Not known to be mutagenic
Reproductive Toxicity: Not identified

Ecological Information

Ecotoxicity: Considered low toxicity to aquatic and terrestrial life
Persistence and Degradability: Readily biodegradable in environment
Bioaccumulation Potential: Not expected to bioaccumulate
Mobility in Soil: Mobile in water, dissipates in soil
Other Effects: No known significant hazards to ecosystems

Disposal Considerations

Waste Treatment Methods: Dispose of contents and containers in accordance with local, regional, national regulations
Disposal of Product: Landfill or incineration at permitted facility
Contaminated Packaging: Rinse thoroughly before recycling or disposal
Special Precautions: Prevent uncontrolled release into environment
Disposal Considerations: Follow municipal, state and federal waste management guidelines

Transport Information

UN Number: Not regulated for transport
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified
Packing Group: Not assigned
Special Precautions for Transport: Protect from physical damage, keep container dry
Transport in Bulk: Not applicable, not a marine pollutant
Labels Required: None required under domestic or international codes

Regulatory Information

Safety, Health and Environmental Regulations: Listed in all major chemical inventories (TSCA, EINECS/ELINCS, DSL, ENCS)
SARA Title III: Not subject to reporting under Section 313
California Prop 65: Not listed
REACH Status: Registered or exempt
Other Local, State, Federal Requirements: Observe specific regulatory requirements for food additives and pharmaceuticals if applicable
Labeling Requirements: None required for non-hazardous substances