Material Safety Data Sheet for Benzaldehyde Propylene Glycol Acetal

Identification

Product Name: Benzaldehyde Propylene Glycol Acetal
Chemical Formula: C10H12O2
CAS Number: 125-73-5
Synonyms: Benzaldehyde, 1,2-propylene glycol acetal; 1,3-dioxolane, 2-(phenylmethyl)-4-methyl-
Recommended Use: Flavoring agent, chemical intermediate, fragrance addition
Supplier/Manufacturer: Contact chemical supplier for details
Contact Details: Emergency phone, address, and email typically located on safety documentation

Hazard Identification

GHS Classification: Flammable liquid (Category 4), Acute toxicity oral (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may be harmful if swallowed, suspected of damaging fertility, may cause respiratory irritation
Pictograms: Exclamation mark, health hazard
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated areas, wear protective gloves, protective clothing, eye protection, face protection
Potential Health Effects: Can cause irritation to eyes and skin, inhalation may lead to respiratory discomfort, prolonged exposure may lead to adverse effects on the central nervous system

Composition / Information on Ingredients

Chemical Name: Benzaldehyde propylene glycol acetal
Percentage: >98% by weight
Impurities: Minor traces of benzaldehyde and propylene glycol may remain post-synthesis
Other Components: No significant impurities expected with standard manufacturing practices
Molecular Weight: 164.20 g/mol

First Aid Measures

Inhalation: Remove person to fresh air, keep at rest in a position comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing immediately, flush skin with plenty of water, consult a physician for continued irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical advice
Ingestion: Rinse mouth, do not induce vomiting without medical advice, seek immediate medical attention
Most Important Symptoms: Redness, burning sensation, temporary impairment of sight, abdominal discomfort on ingestion, dizziness if inhaled

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide (CO2), water spray (to cool containers)
Unsuitable Extinguishing Media: Strong water jets may spread material
Specific Hazards: Flammable vapors may form explosive mixtures with air, combustion may release toxic gases including carbon oxides, product containers may rupture when exposed to fire
Special Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective gear
Firefighting Instructions: Move containers from fire area if safe, cool exposed containers with water spray, prevent run-off into drains and waterways

Accidental Release Measures

Personal Precautions: Avoid breathing vapors or mist, ventilate area, evacuate unnecessary personnel, wear appropriate personal protective equipment (PPE)
Environmental Precautions: Prevent spillage from entering drains or watercourses, inform relevant authorities of large spills
Methods for Clean-Up: Absorb with inert material (e.g., sand, vermiculite), transfer to suitable closed container, clean spill area thoroughly with water and detergent, dispose according to local regulations
Special Disposal Considerations: Contaminated material should be managed as hazardous waste, do not use combustible cleaning materials

Handling and Storage

Handling: Use only in well-ventilated areas, avoid skin and eye contact, avoid inhaling vapors or mist, keep away from sources of ignition, do not eat, drink or smoke when handling
Storage Conditions: Store in tightly closed original container, keep containers in a cool, dry, well-ventilated area, seal drums after use, separate from incompatible materials (such as strong oxidizers and acids), protect from sunlight and heat
Specific End Uses: Industrial and laboratory use, flavor additive, perfumery

Exposure Controls and Personal Protection

Engineering Controls: Local exhaust ventilation, eye wash stations, emergency showers near handling areas, explosion-proof equipment in hazardous locations
Exposure Limits: No occupational exposure limits specifically established, but maintain exposure as low as possible
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), protective goggles or face shield, lab apron or protective clothing, NIOSH-approved respirator for vapor exposure above recommended limits
Hygiene Measures: Wash hands and face thoroughly after handling, do not reuse contaminated clothing without washing, keep work area clean

Physical and Chemical Properties

Appearance: Clear colorless to pale yellow liquid
Odor: Mild, aromatic (reminiscent of bitter almond with less intensity)
Odor Threshold: Detectable at low ppm range
pH: Not applicable
Melting/Freezing Point: Below -20°C
Boiling Point: 244°C at 760 mmHg
Flash Point: Approximately 130°C
Evaporation Rate: Lower than ether
Flammability: May form flammable vapor-air mixtures at elevated temperature
Vapor Pressure: 0.065 mmHg at 25°C
Vapor Density: Heavier than air
Solubility: Slightly soluble in water, soluble in ethanol and organic solvents
Partition Coefficient (n-octanol/water): Estimated logP 2.0-3.0
Autoignition Temperature: Over 300°C
Decomposition Temperature: Not established
Viscosity: Moderate viscosity, similar to light oils

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: No polymerization expected, may react vigorously with strong oxidizers
Conditions to Avoid: Exposure to high temperature, ignition sources, incompatible materials such as acid chlorides, strong acids, alkali metals, or oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, aldehyde fumes, irritating organic vapors
Incompatible Materials: Strong acids, oxidizing agents, alkali metals

Toxicological Information

Acute Toxicity (Oral): LD50 in rats estimated at 200-2000 mg/kg
Acute Toxicity (Dermal): LD50 in rabbits over 2000 mg/kg
Skin Corrosion/Irritation: May cause moderate skin irritation with prolonged contact
Serious Eye Damage/Irritation: Causes eye irritation, risk of reversible damage
Respiratory/Skin Sensitization: Sensitizing effects not well documented
Germ Cell Mutagenicity: Not classified as mutagenic based on available data
Carcinogenicity: No evidence from animal studies for carcinogenicity
Reproductive Toxicity: Data insufficient for classification, structurally similar substances may affect fertility
Specific Target Organ Toxicity: May cause drowsiness or dizziness if inhaled, repeated exposure can affect central nervous system
Aspiration Hazard: Not classified
Likely Routes of Exposure: Inhalation, skin contact, ingestion, eye contact

Ecological Information

Ecotoxicity: Harmful to aquatic life with long lasting effects based on structure-activity data for related acetals
Persistence and Degradability: Expected to undergo slow biodegradation; main breakdown products are benzoic acid derivatives
Bioaccumulation Potential: Moderate potential, logP supports some accumulation in fatty tissues
Mobility in Soil: Moderate mobility, moderately persistent in moist soils
Other Adverse Effects: Limited data on long-term effects, best practice to prevent chemical from entering waterways
Disposal to Environment: Never release into drainage, soil, or aquatic environments beyond permissible limits

Disposal Considerations

Waste Treatment Methods: Incinerate at high temperature in chemical incinerator equipped with afterburner and scrubber, or dispose by licensed waste disposal contractor
Contaminated Packaging: Empty containers must be rinsed thoroughly prior to disposal, discard as hazardous waste
Special Precautions: Follow all local, regional, and national regulations regarding disposal, prevent unauthorized discharge to the environment
Disposal of Small Amounts: Absorb in non-combustible material and place in container for disposal

Transport Information

UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains benzaldehyde propylene glycol acetal)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Not a marine pollutant
Transport Labels: Toxic, keep away from foodstuffs
Precautions for Transport: Package securely, ensure upright transport, prevent any leaks, check temperature compatibility for extended transit, notify carrier of hazardous nature

Regulatory Information

Occupational Health and Safety: OSHA hazardous chemical as defined by 29 CFR 1910.1200
TSCA Status: Subject to reporting and record-keeping, check TSCA Inventory
SARA Title III Section 313: Not listed
REACH Status: Must be registered for manufacture or import in EU above 1 tonne/year
DSL/NDSL (Canada): Verify inclusion prior to use
Other Requirements: Follow directives for chemical labeling, employer communication, accident reporting, and worker training