Product Name: Arterenol Bitartrate
Synonyms: Norepinephrine Bitartrate; L-arterenol hydrotartrate
CAS Number: 108341-18-0
Molecular Formula: C8H11NO3·C4H6O6
Recommended Use: Pharmaceutical intermediate, research chemical
Supplier Contact: Supply chain managers and laboratories distribute this material across clinical and research centers
Emergency Phone Number: Posted on SDS delivered with shipment, as per regulations
Manufacturer: Chemical supply firms recognized by regulatory agencies; batch number and date of manufacture are clearly labeled for tracking purposes
GHS Classification: Acute toxicity (Oral, Dermal, Inhalation) - Category 4; Serious Eye Damage/Irritation - Category 2A; Skin Sensitization - Category 1
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin and eye irritation; may cause allergic skin reaction
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or powder; wear protective gloves and eye protection; wash hands after handling; avoid contact with skin, eyes, and clothing
Chemical Identity: Arterenol Bitartrate (Norepinephrine Bitartrate)
Purity: ≥98% by HPLC
Impurities: Residual solvents or starting material derivatives typically controlled below 0.5%
EINECS Number: 200-601-7
Concentration: 100% (Unless otherwise indicated on packaging)
Other Ingredients: None specified for analytical grade preparation
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses; continue rinsing; seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing; wash exposed skin thoroughly with soap and water; medical advice is required for persistent irritation
Inhalation: Move person to fresh air; support breathing as necessary; call physician if symptoms develop
Ingestion: Rinse mouth; do not induce vomiting; never give anything by mouth to an unconscious person; seek immediate medical care
Acute Symptoms: Headache, skin rash, respiratory irritation, mucous membrane discomfort
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, alcohol foam
Unsuitable Media: Strong jets of water, which may spread fire
Specific Hazards: May emit toxic fumes of carbon monoxide, nitrogen oxides under thermal decomposition
Special Protective Equipment: Firefighters wear full protective gear including self-contained breathing apparatus
Firefighting Techniques: Contain fire with non-combustible barriers and avoid run-off into drains
Explosion Risk: No significant explosion hazard observed in typical laboratory quantities
Personal Precautions: Adequate ventilation in the area; use personal protective equipment recommended for chemical handling
Spill Response: Avoid dust formation; sweep or vacuum up material into a sealed, labeled waste container for approved disposal
Environmental Precaution: Prevent entry into waterways, drains, and soil to reduce environmental impact; report significant spills to local authorities
Decontamination: Clean contaminated surfaces with water and typical laboratory detergent; dry surfaces completely before reuse
Handling: Use only in well-ventilated workplaces; keep away from incompatible substances such as oxidizing agents; avoid generating dust and direct skin or eye contact
Special Handling Notes: Use mechanical exhaust, work inside chemical fume hoods where practical
Storage Conditions: Store at 2-8°C in a tightly closed container, protected from light and moisture
Storage Incompatibilities: Acids, bases, strong oxidizers
Packaging: Preferably in amber glass or plastic containers clearly labeled with product name and hazard warnings
Occupational Exposure Limits: No specific OEL established; minimize exposure in absence of official limit
Engineering Controls: Local exhaust ventilation, safety cabinets for weighing and transfer
Personal Protective Equipment: Protective glasses with side shields; lab coat; chemical-resistant gloves (nitrile or neoprene); NIOSH-approved respirator for airborne concentrations
Hygiene Measures: Wash hands immediately after handling, before eating, or after removing safety gear; avoid eating or drinking near work area
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: 3.0–5.0 (5% solution)
Melting Point: 250 °C (decomposes)
Boiling Point: Not applicable
Solubility: Soluble in water, slightly soluble in ethanol
Vapor Pressure: Not measurable under standard conditions
Partition Coefficient: log Kow -2.5
Flash Point: Not flammable
Other Data: Stable under recommended storage conditions; avoid temperatures above 40 °C
Chemical Stability: Stable at recommended storage temperature and in original sealed container
Conditions to Avoid: High temperatures, exposure to air, acidic or alkaline environments
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, tarry byproducts if burned
Polymerization Hazard: No hazardous polymerization expected
Acute Toxicity: LD50 (oral, rat): 90 mg/kg; data suggests risk through ingestion
Skin Corrosion/Irritation: Irritant to skin on direct contact; repeated or prolonged exposure may result in dermatitis
Eye Damage/Irritation: Causes moderate eye irritation with possible redness and pain
Respiratory Effects: Dust inhalation may cause transient respiratory discomfort
Carcinogenicity: No data supporting classification as carcinogen
Sensitization: May cause allergic reactions through dermal exposure
Chronic Exposure: No reliable human data for ongoing and repeated exposure risks
Toxicity in Aquatic Organisms: No specific measured data, but parent class of catecholamines shows moderate aquatic toxicity
Persistence/Degradability: Likely to degrade under aerobic conditions, but slow in anaerobic regions
Bioaccumulation: Limited potential due to water solubility and low partition coefficient
Mobility: Mobile in aqueous environments; may leach through some soils
Other Hazards: Avoid large releases, as acute effects on aquatic biota possible
Waste Treatment: Chemical waste must be collected in sealed, labeled containers; do not dump in sanitary sewers
Incineration: Incinerate in a chemical waste incinerator equipped with afterburner and scrubber or follow institutional disposal practices
Empty Containers: Rinse thoroughly before disposal; discard in accordance with local, state, and federal requirements
Disposal Legislation: Refer to applicable regional, national, and international regulations
UN Number: Diagnostic substances, not regulated as hazardous under IATA or DOT for standard laboratory quantities
Shipping Name: Chemical, n.o.s. (not otherwise specified)
Hazard Class: Non-regulated or as per largest component if blended
Packaging: Use tightly sealed containers with clear hazard labeling; protect against moisture and impact
Special Precautions: Handle as fragile and potentially hazardous material; notify carrier of special handling requirements
Labeling Requirements: Conforms with OSHA Hazard Communication Standard for health hazards
International Inventories: Listed on international chemical substance inventories where applicable
Health, Safety & Environmental Regulations: Subject to national and local workplace safety protocols
R&D Exemptions: Research and analytical uses may be exempt from some regulatory requirements, subject to institutional safety oversight
Worker Safety: Training required for safe chemical handling; keep SDS accessible at all work areas
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