Chemical Name: (-)-Arterenol bitartrate hydrate
Synonyms: Norepinephrine bitartrate hydrate, Levarterenol bitartrate hydrate
CAS Number: 436-78-8
Molecular Formula: C8H11NO3·C4H6O6·xH2O
Molecular Weight: 337.3 g/mol (hydrate form depends on degree of hydration)
Recommended Use: Laboratory research, pharmaceutical intermediate
Supplier: Check product packaging
Contact Information: Emergency phone number available on safety data label
Classification: Acute Toxicity (Oral and Dermal, Category 4), Eye Irritation (Category 2A), Skin Irritation (Category 2)
GHS Label Elements: Warning (exclamation mark symbol)
Hazard Statements: Harmful if swallowed, causes skin and serious eye irritation
Precautionary Statements: Avoid contact with skin and eyes; wash skin thoroughly after handling
Potential Health Effects: May cause drowsiness, irregular heartbeat, hypertension, and headache with high exposure
Environmental Hazards: Not classified as hazardous, but high concentrations may affect aquatic organisms
Chemical Name: (-)-Arterenol bitartrate hydrate
Synonyms: Norepinephrine bitartrate hydrate
Concentration: 100% (hydrate state varies with humidity)
CAS Number: 436-78-8
Impurities: Does not typically contain significant impurities relevant for classification
Inhalation: Remove to fresh air, keep at rest, consult a physician if symptoms persist
Skin Contact: Wash skin thoroughly with soap and water; remove contaminated clothing
Eye Contact: Immediately flush with water for at least 15 minutes, lift upper and lower eyelids to ensure thorough rinsing; seek medical advice
Ingestion: Rinse mouth; do not induce vomiting unless directed by medical personnel; get medical attention
Most Important Symptoms: Nausea, headache, palpitations, anxiety; contact medical provider for symptoms that escalate
Protection for First Responders: Use personal protective gear, avoid direct contact
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, foam
Unsuitable Media: Strong water jets create dust clouds
Specific Hazards: Emits toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides when burned
Firefighter Protective Equipment: Self-contained breathing apparatus, full protective clothing
Special Procedures: Cool containing vessels with water
Combustion Products: Toxic and irritating fumes
Personal Precautions: Avoid dust formation; use personal protective equipment, including gloves, goggles, and lab coat
Environmental Precautions: Prevent entry into waterways or drains
Spill Cleanup Methods: Evacuate area, ventilate, sweep up material without creating dust, transfer residue to labeled container
Disposal: Follow federal, state, and local regulations
Decontamination: Wash spill area thoroughly after cleanup
Precautions: Minimize dust generation; avoid breathing dust, contact with skin or eyes
Safe Handling Advice: Work in well-ventilated area, use appropriate PPE, wash hands and surfaces after use
Storage Conditions: Store in a tightly closed, labeled container, in a cool, dry, well-ventilated area
Incompatibilities: Keep away from oxidizing agents, acids, and bases
Storage Class: Store with organic solids; prevent moisture ingress
Special Storage Details: Avoid temperature extremes, exposure to light, or humidity
Occupational Exposure Limits: No specific occupational exposure limits established for this compound
Engineering Controls: Handle material inside fume hood or with local exhaust
Personal Protective Equipment (PPE): Chemical-resistant gloves, safety goggles, lab coat
Respiratory Protection: Use NIOSH-approved respirator if dust forms
Hygiene Measures: Wash hands before breaks and at end of work, no eating/drinking/smoking during use
Control of Environmental Exposure: Prevent release into environment, use proper waste containers
Appearance: White or off-white crystalline powder
Odor: No significant odor
Odor Threshold: Not available
pH: Aqueous solution typically acidic
Melting Point/Range: Decomposes before melting (around 220 °C)
Boiling Point: No data (decomposition at high temperature)
Flash Point: Not available
Evaporation Rate: Not applicable
Flammability: Not considered flammable
Explosive Properties: Not expected to present an explosion hazard
Vapor Pressure: Not applicable
Solubility: Freely soluble in water
Partition Coefficient: No data
Auto-ignition Temperature: Product decomposes
Decomposition Temperature: Above 220 °C
Viscosity: Not applicable
Molecular Weight: Approx. 337.3 g/mol (hydrate)
Chemical Stability: Stable under standard conditions for storage and use
Possible Hazards: Dust formation; decomposition by strong acids, bases, or oxidizers
Conditions to Avoid: Excessive heat, direct sunlight, moisture
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Decomposition Products: Emits carbon oxides, nitrogen oxides under fire conditions
Polymerization: Product does not undergo hazardous polymerization
Acute Toxicity: LD50 (oral, rat): 50-400 mg/kg; significant toxicity in high doses
Skin Irritation: Irritating to skin; may cause dermatitis in sensitive individuals
Eye Irritation: Severe irritation possible with direct exposure
Respiratory Effects: Dust inhalation may cause mucous membrane irritation
Sensitization: Possible risk of allergic reactions; avoid repeated or prolonged skin contact
Long-term Effects: Chronic exposure not well documented, but neurotoxic and cardiovascular effects are possible
Mutagenicity/Carcinogenicity: No data available; compound not classified as carcinogenic
Toxicity to Fish: Limited data available, expected to show some acute toxicity at elevated concentrations
Toxicity to Daphnia and Other Aquatic Invertebrates: Not fully documented, but avoid release to water bodies
Persistence and Degradability: Likely degradable under environmental conditions, but ask supplier or check literature for product-specific details
Bioaccumulation: Expected to have low bioaccumulation potential due to solubility in water
Mobility in Soil: Soluble, migrates easily in water
Other Adverse Effects: Avoid contamination of soil and water, follow local disposal rules
Disposal Instructions: Dispose of in a chemical waste incinerator, following all federal, state, and local regulations
Contaminated Packaging: Dispose of as chemical waste; triple rinse with water before discarding
Environmental Precautions: Prevent spillage and release into groundwater, soil, and drains
Waste Code: Not specifically regulated, but consult local waste authorities for details
UN Number: Not regulated for transport
Proper Shipping Name: Not regulated as dangerous shipment
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions for Users: Maintain products in original packaging, avoid sources of contamination, carry SDS during transport
TSCA (USA): Listed or meets eligibility
DSL/NDSL (Canada): Confirm with supplier or local regulations
REACH (EU): Pre-registration may apply; consult ECHA website for updates
OSHA Hazards: Harmful by ingestion, irritant
SARA 313: Not subject to reporting
California Proposition 65: Not known to contain any components listed
Other Inventories: Check specific country requirements
Other Regulatory Information: Product label supplies essential hazard and safety recommendations
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