Product Name: Antimony sodium gluconate
Chemical Formula: C12H16NaO14Sb
Common Synonyms: Sodium antimony gluconate, antimonyl gluconate
Intended Use: Pharmaceutical compound for treatment of leishmaniasis
Manufacturer Information: Manufacturer’s address and contact info required on packaging
Emergency Contact: Medical emergency phone numbers provided by supplier or national poison center
CAS Number: 154-64-5
Hazard Classification: Toxic; hazardous to environment and health when mishandled
GHS Classification: Acute toxicity (oral/dust/inhalation), eye and skin irritation, aquatic toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed or inhaled; risk of serious health effects on prolonged exposure; may irritate eyes and respiratory tract
Pictograms: Skull and crossbones, exclamation mark, environmental hazard symbol
Precautionary Measures: Use protective equipment; avoid breathing dust or fumes; prevent release to environment
Potential Health Effects: Vomiting, abdominal cramps, muscle aches, liver/kidney effects, rare allergic reactions
Environmental Hazards: Harmful to aquatic life with long lasting effects; accumulation in soil and water possible
Main Ingredient: Antimony sodium gluconate
Chemical Concentration: Above 95% by weight
Impurities: Trace sodium compounds, residual organic solvents
Ingredient Classification: Toxic; exact ratios listed in technical data
Inhalation: Remove to fresh air immediately; keep person calm and warm; seek medical help if symptoms develop
Skin Contact: Wash thoroughly with soap and plenty of water; remove contaminated clothing; consult doctor for rashes or discomfort
Eye Contact: Rinse eyes gently under running water for 15 minutes; do not rub; consult physician right away
Ingestion: Rinse mouth; do not induce vomiting; get medical attention promptly; monitor for persistent symptoms
Symptoms to Watch: Nausea, headaches, weakness, shortness of breath, abnormal heart rhythm
Flammability: Not flammable; may decompose to release toxic antimony oxides and carbon compounds in a fire
Suitable Extinguishing Agents: Dry chemical, carbon dioxide, foam, water spray
Special Firefighting Precautions: Wear self-contained breathing apparatus and protective clothing; avoid inhaling fumes
Hazardous Combustion Products: Antimony trioxide, sodium oxide, carbon monoxide, carbon dioxide
Additional Advice: Isolate fire scene; prevent contaminated runoff from entering waterways or soil
Personal Protection: Wear gloves, goggles, mask, protective clothing
Spill Cleanup: Sweep up without raising dust; place in labeled container for safe disposal
Decontamination: Wash spill area with water and mild detergent; ventilate area well
Environmental Precautions: Do not allow to enter drains, groundwater, or surface water; alert authorities in event of large release
Disposal of Collected Material: Follow regulatory guidelines for hazardous chemical waste
Handling: Work in well-ventilated area; avoid contact with skin, eyes, and clothing; do not eat, drink, or smoke in work area
Storage Requirements: Store in original, tightly sealed containers; keep in dry, cool, locked facility; avoid storing near incompatible substances like acids or oxidizers
Protection from Damage: Keep out of reach of children; prevent spills or leaks
Handling Precautions: Use tools and equipment designed for chemical use only
Recommended Engineering Controls: Local exhaust ventilation at source of use; fume hood for laboratory work
Exposure Limits: OSHA PEL (Antimony) = 0.5 mg/m³ (TWA); local limits may vary
Personal Protective Equipment (PPE): Chemical-resistant gloves, safety goggles, protective apron, suitable respiratory protection if ventilation inadequate
General Hygiene: Wash hands and exposed skin thoroughly after use; do not reuse contaminated clothing
Monitoring: Airborne antimony levels should be measured in workplaces at risk for dust or fumes
Appearance: White to off-white crystalline powder
Odor: Odorless
pH (1% solution): Approx. 7.0-8.0
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility in Water: Readily soluble
Density: About 1.95 g/cm³
Vapor Pressure: Not volatile
Other Data: Stable under standard temperature and pressure; hygroscopic
Chemical Stability: Stable under normal conditions
Incompatible Materials: Strong acids, oxidizing agents; avoid mixing with reactive chemicals
Conditions to Avoid: Moisture, heat above 40°C, open flame, direct sunlight
Hazardous Decomposition: Antimony oxides, toxic fumes if heated above decomposition point
Polymerization: Does not polymerize
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 in rats: 115 mg/kg; toxicity may vary between species and individuals
Chronic Effects: Liver and kidney damage, blood disorders after repeated or prolonged exposure
Carcinogenicity: IARC: Antimony compounds possibly carcinogenic to humans (Group 2B)
Other Potential Effects: Gastrointestinal distress, respiratory irritation, muscle weakness, rare allergic reactions
Persistence: Does not degrade easily in natural environments; risk of accumulation
Environmental Mobility: May leach into water and soil; binds strongly to sediment
Aquatic Toxicity: Harmful to aquatic organisms (antimony is toxic to fish and some invertebrates)
Bioaccumulation Potential: Moderate to high; antimony can build up in aquatic food chains
Additional Impact: Spilled material poses contamination risk to water bodies and soil microbial life
Disposal Method: Collect and place waste in approved hazardous waste containers; incinerate at licensed facility or transfer to chemical waste handler
Disposal of Containers: Rinse empty containers before recycling or disposal
Precautions: Do not allow runoff into drains, local water, or soil; follow national and local chemical disposal guidelines
Waste Codes: Refer to EPA Hazardous Waste Codes or regional equivalents
UN Number: UN 3288
Proper Shipping Name: Toxic solid, inorganic, n.o.s. (Antimony sodium gluconate)
Hazard Class: 6.1 (Toxic Substance)
Packing Group: III
Labels Required: Toxic material
Transport Precautions: Protect from moisture, handle with care to prevent spills and leaks
Regulatory Guidelines: Comply with IMDG, IATA, ADR transport requirements as applicable
OSHA Hazard Communication: Classified as hazardous chemical
TSCA Status: Listed
SARA Title III – Section 313: Subject to reporting as an antimony compound
REACH Status (EU): Registration and authorization may apply; reference ECHA database
Canada WHMIS: Classified as toxic material
National/Local Regulations: Product may be regulated under hazardous substance controls; workplace safety and environmental protection rules vary by jurisdiction
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