Product Name: Antimony (III) sodium gluconate
Chemical Formula: C12H22NaO14Sb
Synonyms: Sodium antimony gluconate, Antimonate gluconate
CAS Number: 154-29-0
Recommended Use: Used in pharmaceutical fields, especially as a leishmaniasis treatment
Manufacturer Identification: Supplier address, contact number, and emergency phone
Product Code: Internal SKU, batch references
GHS Classification: Acute Toxicity (Oral) Category 4, Serious Eye Damage Category 2A
Pictograms: Health hazard, exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes serious eye irritation; may cause respiratory irritation
Precautionary Statements: Avoid contact with eyes, skin, and clothing; do not breathe dust or fume; wear protective gear
Potential Health Effects: Ingestion can trigger digestive tract discomfort, including nausea, vomiting, and diarrhea; inhalation exposure can bring on coughing, throat irritation, or headache; prolonged contact may cause dermatitis
Substance: Antimony (III) sodium gluconate
Percentage: 100%
Antimony Content: Typically ranges 8–12% by formula
Impurities: Known trace metals (lead, arsenic) may exist at less than 0.01% as allowable
REACH Registration: Not registered
EC Number: 205-825-7
Inhalation: Relocate person to fresh air, keep comfortable, maintain airway; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; rinse skin with running water for at least 15 minutes; obtain medical advice if irritation develops
Eye Contact: Flush immediately with copious amounts of water for at least 15–20 minutes, lifting eyelids occasionally; get prompt medical evaluation
Ingestion: Rinse mouth, never induce vomiting in unconscious individuals, provide water if person is conscious, immediate medical consultation is vital
Acute Symptoms: Gastrointestinal upset, eye or skin irritation, coughing
Advice to Physician: Treat symptomatically, monitor for systemic antimony toxicity
Suitable Extinguishing Media: Use water spray, carbon dioxide, foam, or dry chemical powders
Specific Hazards: Product is not flammable; toxic, irritating antimony oxide fumes may form
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing
Specific Procedures: Move containers from fire area if safely possible; avoid inhalation of dust or fumes
Combustion Products: Antimony oxides, sodium oxides, carbon oxides
Explosion Data: Not known to present explosion risk under normal use
Personal Precautions: Don protective equipment such as gloves, goggles, and dust mask
Environmental Precautions: Prevent material from entering drains, watercourses, or soil
Cleanup Methods: Sweep up without generating dust, shovel into labeled containers for disposal, ventilate area thoroughly
Containment: Dike substances to prevent spreading; use absorbent materials for dry sweeping
Disposal Considerations: Dispose as hazardous waste in accordance with local, regional, or national requirements
Handling: Use in well-ventilated areas, avoid dust formation, keep container tightly sealed when not in active use, wash hands thoroughly after handling
Storage: Store in a cool, dry, well-ventilated spot; keep away from incompatible materials like strong acids, reducing agents, and oxidizing agents; keep separated from foodstuffs; label containers clearly
Special Precautions: Ground and bond containers during transfer, routinely inspect storage containers for leaks or damage
Occupational Exposure Limits: Antimony compounds OSHA PEL: 0.5 mg/m³ (as Sb), ACGIH TLV: 0.5 mg/m³
Engineering Controls: Use local exhaust ventilation, proper filtration and containment systems
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (nitrile or neoprene preferred), lab coat or chemical apron, NIOSH-approved dust respirator
Hygiene Measures: No eating, drinking, or smoking in work area; wash thoroughly after handling
Environmental Exposure Controls: Prevent material from reaching the environment without adequate treatment or containment
Appearance: White to slightly off-white crystalline powder
Odor: Odorless
pH (in water): About 7 (neutral)
Melting Point: Decomposes before melting
Solubility: Freely soluble in water; insoluble in ethanol, ether
Boiling Point: Not applicable
Flash Point: Not flammable
Vapor Pressure: Negligible
Specific Gravity: Approximately 2.2
Partition Coefficient: Not available
Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: May react with strong acids, strong oxidizing agents, and reducing agents
Conditions to Avoid: High humidity, elevated temperatures, contact with incompatible substances
Decomposition Products: Antimony oxides, sodium oxides, carbon monoxide, and carbon dioxide
Polymerization: Product does not undergo hazardous polymerization
Acute Toxicity Data: Oral LD50 (rat): ~250–400 mg/kg
Skin and Eye Contact: Irritant to skin and eyes; may cause redness, swelling, or discomfort
Chronic Effects: Repeated exposure can lead to symptoms of antimony toxicity, such as abdominal pain, nausea, dermatitis, and damage to the liver or cardiovascular system
Carcinogenicity: Antimony compounds are listed as possible carcinogens (IARC Group 2B)
Mutagenicity/Teratogenicity: No comprehensive studies available, caution warranted
Target Organs: Liver, lungs, gastrointestinal system, skin, heart
Ecotoxicity: Harmful to aquatic life, may cause long-term effects in aquatic environments
Persistence and Degradability: Not biodegradable; antimony ions can persist in soil and water systems
Bioaccumulation Potential: Moderate; accumulation in aquatic organisms has been observed
Mobility in Soil: Compound can be mobile in soil, risk of groundwater contamination exists
Other Adverse Effects: Risk to avian long-term exposure not fully quantified; efforts toward environmental release reduction matter
Disposal Methods: Place in sealed, properly labeled containers for collection by licensed chemical disposal contractor
Special Precautions: Avoid disposal in sewage, waterways, or household garbage; consult national, regional, and local regulations for hazardous waste
Container Disposal: Triple rinse containers, dispose as hazardous waste as required
UN Number: Not classified as dangerous for transport
Shipping Name: Not regulated under current international transport guidelines
Transport Hazard Class: Not assigned
Packing Group: None specified
Environmental Hazards: Not considered marine pollutant at typical quantities, though larger spills may require notification
Special Precautions: Protect containers from physical damage, keep secure during transport, documentation should include chemical name and hazard details
Labeling According to GHS: Hazard pictograms, signal word, hazard and precautionary statements must appear
OSHA Hazard Communication: Covered under 29 CFR 1910.1200 as hazardous
REACH Regulation: Not fully registered
EPA Regulations: Subject to TSCA requirements; waste streams may be RCRA regulated
SARA Title III: Reportable under Section 313 (antimony compounds)
State Regulations: Listed in California Proposition 65 as chemical known to the State to cause cancer
International Inventories: Included, but check country-specific status
Workplace Controls: Occupational health standards apply; maintain records of training and monitoring where users handle significant quantities
Providing high-quality chemical products and logistics solutions for global trade partners.
