Chemical Name: (S)-3-Amino-1,2-propanediol
Synonyms: (S)-1,2-Propanediol, 3-amino-; Serinol; 3-Amino-1,2-dihydroxypropane
CAS Number: 13334-94-0
Molecular Formula: C3H9NO2
Molecular Weight: 91.11 g/mol
Recommended Use: Laboratory chemical, industrial synthesis, pharmaceutical intermediate
Supplier: Chemical manufacturer or distributor’s full address and contact phone number
Emergency Telephone: Emergency contact number as listed on product label
GHS Classification: Acute Toxicity (Oral) Category 5, Eye Irritation Category 2A, Skin Irritation Category 3
Signal Word: Warning
Hazard Statements: May cause mild skin irritation; causes serious eye irritation; harmful if swallowed
Pictograms: Exclamation mark symbol (GHS07)
Precautionary Statements: Wash hands thoroughly after handling; wear protective gloves and eye protection; do not eat, drink, or smoke during use; If in eyes, rinse cautiously with water for several minutes
Unknown Acute Toxicity Percentage: Contains no chemical ingredient present in a significant concentration with unknown toxicity
Substance: (S)-3-Amino-1,2-propanediol
Common Name: Serinol
Chemical Identity: Pure substance, no known significant impurities
Concentration: 99% or higher
EC Number: 236-484-8
Inhalation: Move person to fresh air; if breathing feels labored or symptoms develop, seek medical attention without delay
Skin Contact: Remove contaminated clothing; wash exposed skin thoroughly with plenty of water and mild soap; get medical attention if skin irritation persists
Eye Contact: Rinse gently and thoroughly with running water for at least 15 minutes, lifting eyelids; remove contact lenses if present and easy to do; seek immediate medical attention
Ingestion: Rinse mouth; drink water to dilute; do not induce vomiting: medical advice is needed if symptoms present or if large quantity consumed
Medical Attention: Treat symptomatically; monitor for signs of respiratory distress, skin irritation, or eye damage
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical, or carbon dioxide; water spray only for cooling containers
Unsuitable Extinguishing Media: Do not use direct water jet
Specific Hazards: Combustion may release toxic gases such as nitrogen oxides, carbon monoxide, carbon dioxide
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective clothing in closed spaces
Advice for Firefighters: Move containers from fire area if possible; prevent run off from entering sewers
Personal Precautions: Wear impermeable gloves, chemical splash goggles, long-sleeved clothing; evacuate unnecessary personnel
Environmental Precautions: Do not let large spill enter drains, water courses, or soil
Methods for Containment: Absorb with inert material like sand or diatomaceous earth
Clean-Up Procedures: Collect spilled material in sealable container for disposal; ventilate area well
Additional Requirements: Wash spill area thoroughly after clean up; inform responsible authorities if spill enters environment
Safe Handling Advice: Avoid contact with skin, eyes, and clothing; only use in well-ventilated areas; wear personal protective equipment at all times
Hygiene Measures: Wash hands, face, and exposed skin after handling; do not smoke or consume food/drink in work area
Conditions for Safe Storage: Store tightly closed in dry, cool, well-ventilated location away from oxidizing materials; keep container tightly sealed and labeled
Incompatible Materials: Store away from strong acids, strong oxidizers, and strong bases; avoid storing with reactive chemicals
Exposure Limits: No established occupational exposure limit for this substance
Engineering Controls: Use local exhaust or general room ventilation to keep vapors below exposure guidelines
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or neoprene), chemical splash goggles or safety glasses, and protective clothing
Respiratory Protection: Wear approved respirator when vapor or dust concentrations exceed recommended exposure levels or if ventilation inadequate
Environmental Exposure Controls: Prevent significant spills from entering drains or environment
Appearance: White to off-white crystalline solid
Odor: Slight amine-like odor
Odor Threshold: Information not available
pH: Between 6.0 and 8.0 (aqueous solution, 5%)
Melting Point / Freezing Point: 51 – 54°C
Boiling Point: Decomposes before boiling at standard pressure
Flash Point: >100°C (Closed cup, estimated)
Evaporation Rate: Not applicable
Flammability: Not classified as a flammable solid
Vapor Pressure: Negligible at room temperature
Vapor Density: Not available
Relative Density: 1.18 (Water=1)
Solubility: Completely soluble in water, soluble in ethanol
Partition Coefficient (n-octanol/water): Log Kow: -2.25
Auto-ignition Temperature: Not determined
Decomposition Temperature: Subject to decomposition above 130°C
Viscosity: Not available
Chemical Stability: Stable under recommended storage conditions; may undergo slow oxidation on exposure to air
Reactivity: No dangerous reactivity expected under normal use
Hazardous Reactions: Reacts with strong acids, strong bases, and strong oxidizers
Conditions to Avoid: High heat, open flame, incompatible substances
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide can form on combustion or thermal decomposition
Acute Toxicity (Oral): LD50 (rat) >2000 mg/kg, mildly toxic by ingestion
Acute Toxicity (Dermal): Data not available, no severe effects expected under normal use
Acute Toxicity (Inhalation): Data not available, exposure not likely by vapor for this product
Skin Corrosion/Irritation: May cause mild irritation on prolonged or repeated contact
Serious Eye Damage/Irritation: Risk of strong irritation, redness, and tearing
Respiratory Sensitization: No relevant data found in literature
Skin Sensitization: Not classified due to lack of available sensitization studies
Germ Cell Mutagenicity: Not mutagenic in standard in vitro tests
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Reproductive Toxicity: No evidence from animal studies for reproductive hazard
Specific Target Organ Toxicity (Single Exposure): Not classified as target organ toxin
Specific Target Organ Toxicity (Repeated Exposure): Not classified as target organ toxin
Aspiration Hazard: Not expected to present aspiration hazard
Toxicity to Aquatic Organisms: No data found to suggest acute aquatic toxicity; expected to be low hazard due to high water solubility and rapid biodegradation
Persistence and Degradability: Readily biodegradable under standard test conditions
Bioaccumulative Potential: Potential for bioaccumulation is low (log Kow -2.25)
Mobility in Soil: Very mobile in groundwater and soil due to high solubility
Other Adverse Effects: Release in large quantities may cause oxygen depletion in water bodies leading to adverse aquatic effects
Waste Treatment Methods: Small quantities can be diluted and flushed to drain with plenty of water in accordance with local regulations; bulk quantities require professional chemical disposal
Contaminated Packaging: Rinse empty containers and dispose of as hazardous waste according to applicable local laws
Special Precautions: Prevent material from entering the environment or watercourses in large amounts, always consult local environmental authorities for disposal guidance
Physical/Chemical Properties Affecting Disposal: Highly soluble, non-volatile, non-persistent in most environmental compartments; not considered a priority hazardous waste
UN Number: Not regulated for transport under United Nations Model Regulations, IATA, or IMDG
Proper Shipping Name: Non-Regulated Material
Transport Hazard Class: None assigned
Packing Group: None
Environmental Hazards: No
Transport Precautions: Prevent damage to containers and subsequent leaks, keep segregated from incompatible chemicals during transport
Other Transport Information: Avoid extreme temperature conditions during shipping and handling
US TSCA Inventory: Listed
EU REACH Status: Exempt or registered for research and development
OSHA Hazard Communication Standard: Classified as hazardous
SARA 313: Substance does not contain components subject to reporting requirements
California Prop 65: Not listed as a substance known to cause cancer, birth defects, or reproductive harm
WHMIS Classification (Canada): Not controlled
DSL/NDSL (Canada): Listed
RoHS/ELV Status: Compound not restricted by the European Directive
Other International Regulations: Complies with chemical safety regulations in major jurisdictions, check local requirements for use and handling
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