Alimemazine Tartrate: Material Safety Data Sheet (MSDS)

Identification

Product Name: Alimemazine Tartrate
Chemical Formula: C19H24N2S·C4H6O6
Synonyms: Trimeprazine tartrate
Recommended Use: Antihistamine, sedative, antipruritic
Manufacturer’s Information: Supplier contact available on chemical packaging or company website
CAS Number: 31951-30-9

Hazard Identification

Classification: Acute toxicity (oral), specific target organ toxicity, irritant
Hazard Pictograms: Skull and Crossbones, Exclamation Mark
Signal Word: Danger
Hazard Statements: Toxic if swallowed, may cause drowsiness or dizziness, skin and eye irritation possible, potential for allergic skin reactions
Precautionary Statements: Avoid inhalation and contact with skin or eyes; use only with adequate ventilation; wear protective clothing

Composition / Information on Ingredients

Chemical Name: Alimemazine Tartrate
Concentration: Approximately 100% as active pharmaceutical ingredient
Impurities: Trace process-related impurities, not classified as hazardous at pharmaceutical grade levels

First Aid Measures

Inhalation: Remove person to fresh air, support breathing if necessary, seek medical advice
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, obtain medical attention if irritation persists
Eye Contact: Rinse cautiously with water for at least fifteen minutes, remove contact lenses if present and easy, continue rinsing, get medical advice
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice
Most Important Symptoms: Central nervous system depression, respiratory distress, dizziness, somnolence, possible allergic reaction

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry powder, foam, or carbon dioxide
Special Hazards: Combustion can produce carbon oxides, nitrogen oxides, sulfur oxides, toxic fumes
Protective Equipment: Wear self-contained breathing apparatus, protective suit
Other Advice: Avoid inhalation of fire-generated fumes, cool exposed containers with water spray, evacuate area if necessary

Accidental Release Measures

Personal Precautions: Avoid dust formation, use adequate ventilation, wear suitable personal protective equipment (gloves, eye protection, mask)
Environmental Precautions: Prevent product from entering drains and waterways
Clean-Up Methods: Sweep or scoop up without creating dust, place in suitable container for disposal, wash spill area with water and detergent

Handling and Storage

Handling: Use in well-ventilated place, avoid inhalation and contact with skin or eyes, do not eat or drink while handling, wash hands before breaks
Storage: Keep in tightly closed original container in cool, dry, and well-ventilated location, store away from incompatible materials such as strong oxidizers, acids, or bases, keep away from direct sunlight and heat sources, secure area from unauthorized access

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established, minimize exposure as for pharmaceuticals
Engineering Controls: Use local exhaust ventilation, process enclosures, or other engineering controls
Personal Protection: Use chemical-resistant gloves, protective eyeglasses or goggles, laboratory coat or protective clothing, approved dust mask or respirator
Hygiene Measures: Wash hands and face after handling, remove contaminated clothing and wash before reuse

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or slight odor
Melting Point: 195-200°C
Solubility: Soluble in water, ethanol
pH (1% solution): 4.0-5.0
Boiling Point: Not applicable (decomposes)
Vapor Pressure: Not applicable
Relative Density: Not established
Other Properties: Stable under recommended conditions, sensitive to light, non-volatile

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Not reactive under normal conditions
Incompatible Materials: Strong oxidizing agents, acids, alkalis
Hazardous Decomposition Products: May release carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides upon heating or combustion
Conditions to Avoid: Excessive heat, exposure to light, moisture

Toxicological Information

Acute Toxicity: Oral: toxic, LD50 (rat) reported between 300-1000 mg/kg depending on study
Routes of Exposure: Ingestion, inhalation, skin and eye contact
Symptoms: Sedation, CNS depression, dry mouth, ataxia, anticholinergic effects, skin or eye irritation, possible allergic response
Chronic Effects: Repeated exposure can affect nervous system or liver function
Carcinogenicity: No data suggesting carcinogenic potential
Reproductive Effects: No clear evidence of teratogenicity or effects on fertility at therapeutic doses

Ecological Information

Ecotoxicity: Not expected to pose significant hazard to aquatic life at low concentrations typical of pharmaceutical use
Persistence and Degradability: Limited data available, suspected to be slowly biodegradable
Bioaccumulation Potential: Expected to be low
Mobility in Soil: Moderately mobile based on solubility
Other Information: Avoid uncontrolled release to the environment

Disposal Considerations

Waste Treatment Methods: Incinerate in a facility equipped for chemical waste or dispose of in accordance with local regulations
Waste Code: Classified as hazardous pharmaceutical waste in many jurisdictions
Packaging: Triple rinse containers, dispose of as hazardous waste
Special Precautions: Do not dispose into drains, watercourses, or household waste

Transport Information

UN Number: Not regulated as a dangerous good for transport
Proper Shipping Name: Pharmaceutical product, not otherwise specified
Transport Hazard Class: Not classified
Packing Group: Not assigned
Special Transport Precautions: Prevent physical damage during transport, protect from moisture, direct sunlight and high temperatures

Regulatory Information

Labeling: Label in accordance with local, national, and international regulations for hazardous chemicals
Inventory Status: Listed in pharmaceutical ingredient registries in most countries
Regulations: Subject to pharmaceutical and workplace safety legislation, including OSHA standards in the US, REACH in the EU, and other local workplace exposure standards
Other Requirements: Safety assessment and proper training required for workers handling the material, regular review of safety protocols recommended