Product Name: (6S)-5-Methyltetrahydrofolate Calcium
Synonyms: L-5-MTHF Calcium, Levomefolate Calcium, L-methylfolate Calcium
CAS Number: 151533-22-1
Manufacturer: [Insert Manufacturer Name and Address]
Recommended Use: Nutritional supplement, pharmaceutical ingredient
Restrictions on Use: Not for direct consumer use in unformulated form
Emergency Contact: [Insert Emergency Number]
Supplier Phone: [Insert Supplier Phone Number]
Classification: Not hazardous according to GHS criteria
Signal Word: None
Hazard Statements: No significant hazards identified under normal handling
Precautionary Statements: Avoid contact with skin and eyes. Prevent dust formation. Handle using standard laboratory safety practices.
Pictograms: None required
Other Hazards: Product can form combustible dust concentrations in air under certain conditions.
Route of Exposure: Inhalation, skin, eye, ingestion
Health Effects: May cause mild irritation to skin, eyes, or respiratory tract if handled improperly
Chemical Identity: (6S)-5-Methyltetrahydrofolate Calcium
Chemical Formula: C20H23CaN7O6
Molecular Weight: 497.52 g/mol
Concentration: ≥98%
Impurities: None having significant impact on classification as per supplier registration
Other Information: No hazardous additives or solvents present
Inhalation: Move person to fresh air. Seek medical advice if irritation or discomfort persists.
Skin Contact: Wash with plenty of water and soap. Remove contaminated clothing. Contact physician if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention if irritation continues.
Ingestion: Rinse mouth with water. Never give anything by mouth to an unconscious person. Seek medical advice if symptoms appear.
Most Important Symptoms: Slight irritation possible to exposed tissue
Advice for First Responders: Provide symptomatic treatment. No special equipment required beyond standard PPE.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: High-pressure water jets may spread dust
Fire Hazards: Product itself is not flammable, but as a powder, can accumulate static charges and ignite dust-air mixtures
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Special Procedures: Move containers away from fire if safe. Cool containers with water spray. Prevent fire-fighting water from entering drains.
Hazardous Combustion Products: Carbon oxides, nitrogen oxides, calcium oxide, irritating gases or vapors
Personal Precautions: Avoid breathing dust. Avoid contact with eyes and skin.
Protective Equipment: Wear suitable protective gloves, safety glasses, and protective clothing.
Emergency Procedures: Evacuate unnecessary personnel. Ensure adequate ventilation. Eliminate sources of ignition.
Spill Cleanup Methods: Sweep up material and place in a labeled container for disposal. Minimize dust formation.
Environmental Precautions: Prevent substance from entering drains, surface and ground water.
Disposal: Refer to section on Disposal Considerations. Clean spill area with water.
Handling: Use in well-ventilated area. Minimize creation of airborne dust. Avoid inhalation and contact with skin, eyes, clothing. Wash hands after use.
Storage Conditions: Keep container tightly closed in a cool, dry, well-ventilated place. Store away from incompatible materials such as strong oxidizers or acids.
Packaging Materials: Use original packaging or containers compatible with product. Protect from moisture and light.
Special Procedures: Keep away from food, beverages, and animal feed.
Engineering Controls: Use local exhaust systems or process enclosures to reduce dust exposure. Eyewash stations and emergency showers should be accessible.
Exposure Limits: No established occupational exposure limits for this compound.
Personal Protective Equipment (PPE): Safety glasses or goggles, chemical-resistant gloves (nitrile or PVC), protective clothing.
Respiratory Protection: For dusty conditions, use a dust mask or NIOSH-approved respirator.
Hygiene Measures: Do not eat, drink, or smoke during use. Wash hands before breaks and at end of work.
Environmental Controls: Prevent spillage or leakage into water sources.
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 7 – 8 (1% solution in water)
Melting Point: Not determined due to decomposition
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Flammability: Not classed as flammable, but fine dust may form explosive mixtures with air
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Solubility: Soluble in water
Partition Coefficient: Log Kow not determined
Auto-ignition Temperature: No data available
Decomposition Temperature: Decomposes before boiling
Viscosity: Not applicable
Other Data: Stable under normal handling conditions
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, light, moisture, strong oxidizers, acids
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: Decomposes releasing nitrogen oxides, carbon oxides, and calcium oxide
Reactivity: No known dangerous reactions during normal processing and storage
Acute Toxicity: Not classified as acutely toxic. LD50 (oral, rat): >2000 mg/kg
Skin Irritation: May cause slight, transient irritation
Eye Irritation: May cause minor irritation
Respiratory Effects: Dust may be irritating to respiratory tract
Sensitization: Not considered a sensitizer based on available data
Chronic Effects: No long-term effects known at occupational exposure levels
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity: No evidence of mutagenicity in standard assays
Reproductive Toxicity: No known risks at normal occupational exposure levels
Ecotoxicity: No significant hazards to aquatic environments at low concentrations. Not regarded as harmful for aquatic life.
Persistence and Degradability: Expected to degrade under environmental conditions; not considered persistent.
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: Likely to have moderate to high mobility in soil due to water solubility
Other Adverse Effects: No known adverse effects on the environment based on available data.
Disposal to Waterways: Avoid uncontrolled release to surface water and groundwater.
Disposal Methods: Dispose of in accordance with local, regional, and national regulations. Send to approved disposal facility.
Contaminated Packaging: Rinse thoroughly before recycling or disposal. Contact licensed waste disposal service to properly handle empty containers.
Waste Code: Not classified as hazardous waste according to federal regulations
Recommendations: Do not dispose of residues in household waste or local water systems.
UN Number: Not regulated for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as dangerous according to ADR, IMDG, IATA
Packing Group: Not applicable
Environmental Hazards: Not classified as a marine pollutant
Special Precautions: Transport in covered vehicles, away from direct sunlight, moisture, and heat sources.
Additional Information: Handle containers with care to avoid spillage and dust formation
OSHA Hazard Communication Status: Not considered hazardous
TSCA Inventory: Listed or exempt
DSL/NDSL (Canada): Listed or exempt
REACH Status (EU): Registered or exempt based on intended use
Other Regulatory Listings: Not subject to any chemical-specific reporting requirements
Label Elements: None required
Restrictions: For manufacturing or formulation use only, not for direct adult or pediatric consumption without processing.
Other Regulatory Info: This product is not subject to SEVESO III Directive, not listed as a hazardous substance under SARA Title III.
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