Product Name: 3-(Isopropylamino)-1,2-Propanediol
Chemical Formula: C6H15NO2
CAS Number: 2162-25-8
Synonyms: Isopropylamino-1,2-propanediol, IPA-PD
Recommended Use: Research, chemical intermediate, pharmaceutical raw material
Manufacturer: Details available on product packaging
Emergency Contact: Local poison control or manufacturer’s emergency line
Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity, single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; May cause respiratory irritation; Can provoke mild skin irritation.
Precautionary Statements: Avoid breathing dust, fumes, gas, mist, vapors, spray; Wash hands thoroughly after handling; Use only outdoors or in a well-ventilated area; Wear eye protection, protective gloves; If in eyes, rinse cautiously with water for several minutes; Remove contact lenses if present and easy to do – continue rinsing.
Pictogram: Exclamation mark (GHS07)
Chemical Name: 3-(Isopropylamino)-1,2-Propanediol
Concentration: Greater than 98% by weight
Impurities: Water (less than 1%), unreacted starting materials (trace amounts)
Other Components: No significant additives or stabilizers
General Advice: Seek medical attention if symptoms persist or develop.
Inhalation: Remove person to fresh air. Keep comfortable for breathing. Call a physician if breathing becomes difficult.
Skin Contact: Wash affected area with soap and plenty of water. Remove contaminated clothing and shoes. Obtain medical advice if irritation persists.
Eye Contact: Rinse opened eyes cautiously for at least 15 minutes with plenty of water. Remove contact lenses if possible during rinsing. Seek prompt medical advice.
Ingestion: Rinse mouth with water; do not induce vomiting. Seek immediate medical attention.
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide.
Hazards During Fire: May produce toxic and/or irritating fumes including nitrogen oxides, carbon monoxide, carbon dioxide.
Protective Equipment: Firefighters should use full protective gear including self-contained breathing apparatus.
Specific Methods: Cool exposed containers with water spray; avoid runoff into sewers and waterways.
Flash Point: Data not available; treat as combustible.
Personal Precautions: Wear appropriate respiratory protection, safety goggles, chemical-resistant gloves.
Environmental Precautions: Prevent leakage into drains, water courses, and soil.
Spill Cleanup Methods: Avoid dust formation, ventilate area, use inert absorbent (such as sand, earth) to pick up material and place in suitable labelled disposal containers. Wash spill area with water.
Disposal: Collect contaminated absorbent for disposal according to local, regional, national, and international regulations.
Handling: Keep containers tightly closed. Avoid inhalation, ingestion, and skin or eye contact. Provide adequate ventilation in work areas. Wash hands and face after use. Avoid contact with incompatible substances.
Storage: Store in a cool, dry, well-ventilated environment away from heat, ignition sources, and direct sunlight. Maintain original packaging or use corrosion-resistant containers. Store away from acids, oxidizers, and strong bases.
Exposure Limits: No established exposure limits; use general workplace standards.
Engineering Controls: Local exhaust ventilation or other engineering controls to keep airborne concentrations as low as possible.
Personal Protective Equipment: Splash goggles, impervious gloves, lab coat or suitable long-sleeve clothing, approved respirator (if ventilation is inadequate).
Hygiene Measures: Wash hands before breaks and after handling. Do not eat, drink or smoke during use. Remove contaminated clothing before entering eating areas.
Appearance: Clear to slightly yellowish viscous liquid or crystalline solid
Odor: Mild, amine-like
Odor Threshold: No information available
pH: 6.5 - 8 (aqueous solution)
Melting Point/Freezing Point: 40-45°C
Boiling Point: 187°C at 760 mmHg
Flash Point: Above 80°C (closed cup estimate)
Evaporation Rate: No data
Flammability: No data supporting flammability under normal handling
Vapor Pressure: Less than 0.1 mmHg at 25°C
Density: 1.04 - 1.06 g/cm³ at 25°C
Solubility: Freely soluble in water and most organic solvents
Partition Coefficient (n-octanol/water): No data available
Decomposition Temperature: Not determined
Viscosity: No data available
Chemical Stability: Stable under normal temperature and pressures.
Conditions to Avoid: Excessive heat, open flames, incompatible materials.
Incompatible Materials: Strong oxidizers, strong acids, strong bases.
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, ammonia.
Polymerization: Hazardous reactions do not occur under recommended handling.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Toxicity: Ingestion causes mild gastrointestinal irritation, nausea, headache; inhalation produces respiratory or throat discomfort; eye and skin contact results in irritation and possible mild burns.
Chronic Effects: Long-term or repeated exposure can dry out skin, increase susceptibility to dermatitis, sensitize respiratory tract.
Carcinogenicity: No components listed as carcinogens by IARC, NTP, ACGIH, OSHA.
Mutagenicity: Not expected to be mutagenic under normal use.
Other Data: Seek medical attention for any persistent or worrisome symptoms.
Toxicity to Aquatic Life: Data limited, but expected to cause low to moderate toxicity based on structural similarities to other alkanolamines.
Persistence and Degradability: Readily biodegradable under aerobic conditions.
Bioaccumulation Potential: Low potential based on water solubility and structure.
Mobility in Soil: High mobility due to water solubility but unlikely to persist in the environment.
Other ecotoxicity information: Prevent large volumes from entering waterways or drains to minimize risk to aquatic organisms.
Waste Disposal: Chemical waste must be handled and disposed of as hazardous waste. Use licensed chemical waste disposal contractor.
Contaminated Packaging: Dispose of as chemical waste following local regulations. Empty containers may retain residues.
Discharge Restrictions: Do not pour untreated material into drains, water bodies, or on the ground.
Recycling: Consider recycling or reusing for chemical processes if feasible and permitted by local regulations.
UN Number: Not regulated for transportation under UN, IMDG, IATA codes
Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified
Packing Group: Not applicable
Special Precautions: Keep container tightly closed in secure, upright position. Prevent leaking and spillage during transit. Utilize secondary containment if needed.
Inventory Status: Present in EINECS, TSCA, DSL inventories.
Signal Word per GHS: Warning
Hazard Categories: Acute toxicity (inhalation, skin, eyes), Specific target organ toxicity
Reporting Requirements: Not subject to mandatory reporting under SARA Title III, Section 313; not listed by California Prop 65.
Labelling Requirements: Follow workplace hazardous chemical labeling; provide access to this MSDS in the work area.
Other Regulatory Data: Users must comply with all local, state, and federal chemical safety laws relevant to handling, storage, and disposal.
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