MSDS of 3-Dimethylamino-1,2-Propanediol (N,N-Dimethyl-3-Amino-1-Propanediol)

Identification

Product Name: 3-Dimethylamino-1,2-Propanediol
Other Names: N,N-Dimethyl-3-Amino-1-Propanediol
CAS Number: 104-82-5
Molecular Formula: C5H13NO2
Molecular Weight: 119.16 g/mol
Recommended Use: Industrial applications including chemical synthesis, pharmaceutical intermediates, surfactant production
Supplier Details: Add relevant company address, contact telephone, email
Emergency Number: Enter emergency contact number available 24 hours

Hazard Identification

GHS Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Acute toxicity (oral, Category 4)
Signal Word: Warning
Hazard Statements: Causes skin irritation, Causes serious eye irritation, Harmful if swallowed
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust/vapors, Wash skin thoroughly after handling, Wear protective gloves/protective clothing/eye protection/face protection, If swallowed: call a poison control center or doctor, If on skin: Wash with plenty of water, If in eyes: Rinse cautiously with water for several minutes

Composition / Information on Ingredients

Chemical Name: 3-Dimethylamino-1,2-Propanediol
CAS Number: 104-82-5
Concentration: 98-100% pure
Impurities: Water (<2%), trace organic residues, not considered hazardous at typical concentrations
Additives: None

First Aid Measures

Inhalation: Remove person to fresh air, keep comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Rinse skin with soap and water for at least 15 minutes, remove contaminated clothing, seek medical attention for irritation
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, lift eyelids occasionally, seek medical attention promptly
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, seek immediate medical attention
Most important symptoms/effects: Redness, itching, burning of eyes or skin, nausea if ingested, possible dizziness or headache from inhalation
Notes to Physician: Treat symptomatically, observe for respiratory distress or mucous membrane involvement

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Hazards from Fire: Product can form toxic fumes under fire conditions including nitrogen oxides, carbon monoxide, carbon dioxide
Special Protective Equipment: Firefighters wear self-contained breathing apparatus and chemical-resistant clothing
Specific Hazards: Vapors may be heavier than air, may accumulate in confined or low-lying areas, increasing the risk during fire
Advice for Firefighters: Move containers away from fire area if safe, stay upwind to avoid hazardous smoke, cool containers with water spray to prevent pressure build-up

Accidental Release Measures

Personal Precautions: Wear adequate PPE—gloves, protective clothing, eye/face protection, prevent inhalation of vapors
Environmental Precautions: Prevent material from entering drains, sewers, waterways or soil, contain spill with dikes or barriers
Methods for Clean-up: Absorb spill with inert material such as sand, earth, or vermiculite, shovel into appropriate closed containers
Decontamination: Wash residue with large amounts of water, ventilate area, dispose of waste according to local, regional, national, and international regulations
Emergency Procedures: Evacuate unnecessary personnel, ventilate area, avoid walking through spilled material

Handling and Storage

Handling: Use in well-ventilated areas, avoid skin and eye contact, wear protective gear at all times, keep containers closed when not in use, wash thoroughly after handling, do not eat, drink, or smoke while using this chemical
Storage: Store in cool, dry, well-ventilated location away from incompatible substances such as acids and oxidizing agents, keep container tightly closed, protect from moisture, clearly label storage area
Other Precautions: Keep away from sources of ignition, avoid prolonged or repeated exposure, inspect containers regularly for leaks or damage

Exposure Controls and Personal Protection

Engineering Controls: Local exhaust ventilation preferred, eyewash stations and safety showers accessible near work area, keep air levels below recommended exposure limits
Occupational Exposure Limits: No specific occupational exposure limits established, handle as if moderate hazard
Personal Protection: Wear chemical-resistant gloves (nitrile or butyl recommended), long-sleeve protective clothing, chemical splash goggles, face shield if splash risk, use approved respirator if ventilation inadequate
Hygiene Measures: Do not eat, drink or smoke during use, wash hands and face after handling, remove and clean contaminated clothing before reuse

Physical and Chemical Properties

Appearance: Colorless to pale yellow viscous liquid or crystalline solid
Odor: Slight amine odor
Melting Point: 46-49°C
Boiling Point: 219-223°C
Flash Point: 126°C (open cup)
Solubility: Miscible with water
Vapor Pressure: <1 mm Hg (at 20°C)
Density: 1.026 g/cm³ (at 25°C)
pH: Typically alkaline in aqueous solution
Viscosity: Moderate, increases at lower temperatures
Other Data: Not volatile under standard conditions, stable under normal temperatures and pressures

Stability and Reactivity

Chemical Stability: Stable under normal conditions, avoiding extremes of temperature and moisture
Reactivity: Can react with strong acids to generate heat, toxic gases can be formed on contact
Hazardous Reactions: Incompatible with strong oxidizers (e.g., peroxides, nitric acid), strong acids
Decomposition Products: Can evolve nitrogen oxides, carbon oxides, ammonia on decomposition
Conditions to Avoid: Excessive heat, open flame, contact with acidic or oxidizing materials, moisture exposure
Polymerization: Product does not polymerize under recommended storage and use conditions

Toxicological Information

Acute Toxicity: Oral LD50 rat: 1,200-2,000 mg/kg (estimates from similar compounds)
Skin Contact: Moderate irritation possible with extended exposure
Eye Contact: Causes eye irritation, reddening, watering, possible corneal injury
Inhalation: Limited data, may cause nose and throat irritation, dizziness, headache at high vapor concentrations
Chronic Effects: No reliable data on chronic toxicity, avoid repeated or prolonged exposure
Sensitization: Not expected, monitor for allergic reaction symptoms
Carcinogenicity: No components listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity: Not known to be mutagenic in animal tests
Reproductive Toxicity: Insufficient animal data, use caution to minimize exposure

Ecological Information

Ecotoxicity: Not highly toxic to aquatic life based on calculation, but may cause local damage in high concentrations
Persistence and Degradability: Expected to be biodegradable in soil and water, but rates of breakdown depend on local conditions
Bioaccumulation: Low potential based on physicochemical properties, unlikely to accumulate in living tissues
Mobility in Soil: Highly mobile due to water solubility, may leach into groundwater if released in significant amounts
Other Adverse Effects: Avoid uncontrolled release in environment, spills into waterways can disrupt local ecosystems

Disposal Considerations

Disposal Methods: Dispose of in accordance with local, state, and federal regulations, do not discharge to surface water or sewage systems, incineration in approved facility preferred
Contaminated Packaging: Containers that cannot be cleaned must be disposed of as chemical waste, triple rinse before disposal if permitted
Special Precautions: Handle waste as hazardous, don't mix with incompatible chemicals prior to disposal, seek appropriate regulatory guidance for large volumes

Transport Information

UN Number: Not classified as a dangerous good under most transport regulations
Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Transport Precautions: Keep containers tightly closed and upright, protect from direct sunlight and extreme temperatures, label all packages clearly during transit

Regulatory Information

OSHA: Not specifically regulated
TSCA Inventory: Listed
REACH Status: Registered, maintained within use limitations
SARA Title III: Not listed under Section 302/304/313
California Prop 65: Not listed
Other Regulations: Observe all relevant workplace health and safety guidelines for handling, occupational exposure, emergency planning and environmental protection
Additional Notes: Ensure all staff are trained on risks and safety protocols, keep SDS accessible in work areas at all times, update SDS document whenever process or supplier changes