Product Name: 3-Chloro-2-methyl-1-propanol
Other Names: 3-Chloro-2-methylpropan-1-ol
CAS Number: 33315-13-2
Recommended Use: Research and industrial synthesis
Supplier: Refer to purchase documentation for details
Emergency Contact: Local poison control center or company emergency line as indicated on product label
Molecular Formula: C4H9ClO
Molecular Weight: 108.57 g/mol
GHS Classification: Acute Toxicity (Oral) – Category 4, Skin Irritant – Category 2, Eye Irritant – Category 2A
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin and eye irritation; harmful in contact with skin and if inhaled
Precautionary Statements: Wear protective gloves and eye protection, avoid inhalation of vapors or mist, wash exposed skin thoroughly after handling, do not eat, drink, or smoke during use
Physical Hazards: Non-combustible under normal conditions
Health Hazards: Eye and respiratory tract irritation, nausea, dizziness possible at high concentrations, can aggravate existing dermatological and respiratory conditions
Environmental Hazards: Toxic to aquatic organisms with long-lasting effects reported
Chemical Name: 3-Chloro-2-methyl-1-propanol
Percent Composition: ≥99%
Impurities: Trace residuals from synthesis including unidentified organic byproducts, concentrations less than 1%
Synonyms: No notable synonyms identified for this compound, industry refers to direct IUPAC name
Inhalation: Remove exposed person to fresh air, keep at rest in a position comfortable for breathing, seek medical attention if symptoms persist such as coughing or difficulty breathing
Skin Contact: Remove contaminated clothing and wash skin thoroughly with soap and water, seek medical assistance if irritation develops or persists
Eye Contact: Rinse cautiously with water for 15–20 minutes, remove contact lenses after first 5 minutes if present and easy to do, continue rinsing and obtain medical help
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel, seek prompt medical evaluation and provide SDS information to responders
Notes to Physician: Symptomatic treatment recommended; respiratory or nervous system symptoms require monitoring for delayed onset
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Media: Direct water jets may spread spilled substance
Hazardous Combustion Products: Hydrogen chloride, carbon oxides, choking fumes
Protective Equipment for Firefighters: Full protective suit and self-contained breathing apparatus
Special Procedures: Move containers from area if it can be done safely, use water to cool unopened containers, prevent firewater runoff from contaminating waterways
Personal Precautions: Evacuate area, use proper personal protection (see below), ventilate closed spaces
Environmental Precautions: Prevent further leakage or spillage if safe to do, avoid discharge into drains, surface waters, or soil
Spill Cleanup Methods: Absorb with inert material (sand, earth), transfer to suitable, labeled chemical waste container, ventilate affected space, dispose of according to local and national regulations
Emergency Procedures: Isolate hazard area, keep unauthorized personnel away, provide adequate exhaust ventilation to prevent vapor buildup
Handling: Use only in well-ventilated locations, avoid contact with eyes, skin, and clothing, wash hands thoroughly after handling, use proper laboratory protocols to minimize spillage and vapor formation
Storage: Keep in tightly closed container in a cool, dry, well-ventilated area, segregate from incompatible materials (strong bases, oxidizers), store at room temperature, ensure containers are clearly labeled
Incompatibilities: Strong oxidizing agents, strong bases
Storage Class: Chemical storage, separate from food or animal feed
Engineering Controls: Work in chemical fume hood or with adequate local exhaust ventilation, provide eyewash stations and safety showers
Personal Protection: Chemical resistant gloves (nitrile recommended), safety goggles or faceshield, lab coat and closed footwear, use respiratory protection if ventilation is inadequate or exposure limits exceeded
Exposure Limits: No established OSHA, ACGIH, or NIOSH exposure limits; keep exposures as low as possible using ALARA (As Low As Reasonably Achievable) principles
Hygiene Measures: Do not eat, drink, or smoke during use, wash hands and any exposed skin before leaving work area
Appearance: Clear to pale yellow liquid
Odor: Mild, somewhat sweet
Odor Threshold: Not established
pH: Not applicable (neutral organic liquid)
Melting Point / Freezing Point: Approximately -25°C
Boiling Point / Range: 150–155°C
Flash Point: Above 65°C (closed cup)
Evaporation Rate: Not measured
Flammability: Not classified as flammable
Vapor Pressure: 1.3 mmHg at 20°C (approximate)
Vapor Density: Greater than air
Relative Density: 1.09 g/cm³ at 20°C
Solubility in Water: Soluble
Partition Coefficient (log Kow): Estimated 0.7–1.2 (data limited)
Autoignition Temperature: Not determined
Decomposition Temperature: Not established
Viscosity: Not measured
Chemical Stability: Stable under recommended storage and handling conditions
Incompatible Materials: Strong oxidizers, strong bases, acids
Hazardous Decomposition: Hydrogen chloride fumes and other toxic vapors on combustion
Reactivity: May react slowly with base, can degrade with moisture over extended storage
Hazardous Polymerization: Not expected to occur
Conditions to Avoid: Elevated temperatures, exposure to strong alkaline or oxidative environments, sources of ignition during handling of vapor-rich mixtures
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; oral rat LD50 estimated 250–500 mg/kg
Skin Corrosion/Irritation: Causes irritation in rabbit and mouse dermal studies
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation; conjunctival redness possible
Respiratory Sensitization: Not tested, similar compounds may provoke coughing on inhalation
Skin Sensitization: No data available for this compound; other chlorinated alcohols have low sensitization potential
Carcinogenicity: No long-term studies available; not listed by IARC, NTP, or OSHA
Mutagenicity: In vitro data lacking
Reproductive Toxicity: No specific data available, prudent to avoid chronic or high exposures
Target Organs: Eyes, skin, respiratory system
Relevant Routes of Exposure: Inhalation, ingestion, dermal contact
Symptoms: Irritation, dizziness, nausea, skin dryness, possible headache after high exposure
Ecotoxicity: Toxic to aquatic life, based on similar chlorinated alcohols; estimated LC50 (fish, 96 hrs): 10–50 mg/L
Persistence and Degradability: Expected to be readily biodegradable in standard tests
Bioaccumulative Potential: Low, based on calculated log Kow
Mobility in Soil: Likely to have moderate to high soil mobility due to water solubility
Other Adverse Effects: No data on terrestrial toxicity or bioaccumulation in wildlife reported
Disposal Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber, or dispose of in accordance with local, state, and federal regulations governing hazardous organic chemicals
Contaminated Packaging: Triple-rinse containers then offer for recycling or reconditioning if permissible; otherwise, treat as hazardous waste
Environmental Caution: Do not discharge to surface water, drains, sewers, or soil
UN Number: UN 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains 3-Chloro-2-methyl-1-propanol)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Label Requirement: Toxic
Special Precautions: Secure containers to prevent leakage during transport, avoid mixing with incompatible substances in transit
Transport by Air/Rail/Sea: Refer to relevant national and international regulations (IATA, IMDG, ADR/RID)
TSCA Status: Listed or meets the requirements for exemption
EU REACH Status: Registration may be required depending on tonnage and use
SARA Title III (Sections 311/312): Acute health hazard
SARA Title III (Section 313): Not listed
California Prop 65: Not listed as of latest update
WHMIS (Canada): Classified as toxic, requires workplace labeling and training
Other Regulations: Safety training and local chemical hygiene protocols address workplace use; check regional and national regulatory frameworks for restrictions or further reporting needs
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