Product Name: 3-(4-Chlorophenoxy)-1,2-propanediol
Chemical Formula: C9H11ClO3
Synonyms: Glycerol, mono(4-chlorophenyl) ether; 4-Chlorophenyl Glycidyl Ether
CAS Number: 2153-25-3
Manufacturer Details: Chemical manufacturing facility, emergency line available 24/7
Recommended Uses: Intermediate in chemical synthesis, laboratory use
Restrictions: Not intended for pharmaceutical, veterinary, or household applications
Classification: Harmful if swallowed, may cause respiratory irritation, suspected of causing skin or eye irritation
Signal Word: Warning
Hazard Statements: May cause harmful effects on central nervous system, skin, and eyes
Pictograms: Exclamation Mark (Irritant), Health Hazard
Precautionary Measures: Avoid inhalation, ingestion, or contact with skin and eyes
Potential Acute Health Effects: May produce coughing, nausea, headache, or temporary dizziness
Potential Chronic Health Effects: Prolonged or repeated exposure can cause dermatitis or sensitization
Environmental Hazards: Releases may damage aquatic environments
Chemical Name: 3-(4-Chlorophenoxy)-1,2-propanediol
PURITY: ≥98%
Impurities: Trace organic byproducts, residual solvents below 0.5%
Other Ingredients: This product contains no additional hazardous components as defined by OSHA or GHS
Molecular Weight: 202.64 g/mol
Inhalation: Move to fresh air, keep at rest in a position comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, contact physician if irritation develops
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present and easy to do, seek immediate medical advice
Ingestion: Rinse mouth with water, do not induce vomiting, observe for symptoms, consult a healthcare professional
Most Important Symptoms: Irritation, nausea, coughing, mild inflammation, headache
Advice to Physicians: Symptomatic treatment, monitor respiratory and cardiovascular functions in severe cases
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, or water spray
Unsuitable Extinguishing Media: High pressure water jets may spread product
Specific Hazards: May decompose under fire conditions, releasing hydrogen chloride, chlorinated compounds, or carbon oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Advice for Firefighters: Withdraw immediately if rising sound from venting safety devices or discoloration of container occurs
Hazardous Combustion Products: Hydrogen chloride gas, phenolic vapors, carbon monoxide, and carbon dioxide may form
Personal Precautions: Wear protective gloves, goggles, lab coat, and face protection
Environmental Precautions: Prevent entry into drains, water courses, or soil
Spill Containment: Dike area to prevent spreading, evacuate non-essential personnel
Cleanup Methods: For small spills, absorb with inert material (e.g., sand or earth), collect and place in appropriate container for disposal
Decontamination: Clean residue with soap or appropriate detergent solution, ventilate spill area
Reporting: Notify local environmental authorities if significant amounts reach environment
Handling Precautions: Use in well-ventilated areas, avoid creating dust or aerosols, do not eat, drink, or smoke while using this product
Hygiene Practices: Wash hands after handling, remove contaminated clothing and wash before reuse
Storage Conditions: Keep container tightly closed, store at controlled room temperature (15–30°C), away from direct sunlight and incompatible chemicals
Incompatible Materials: Strong oxidizers, acids, alkalis, and amines
Packaging Requirements: Store in corrosion-resistant, tightly sealed containers
Exposure Limits: No established occupational exposure limit, keep airborne concentrations as low as possible
Engineering Controls: Use fume hood or local exhaust ventilation to minimize exposure
Personal Protective Equipment: Chemical-resistant gloves, anti-splash goggles, lab coats or coveralls, closed footwear
Respiratory Protection: Wear NIOSH-approved respirator in cases of insufficient ventilation or dust formation
Environmental Controls: Prevent environmental release, collect and properly dispose of contaminated materials
Monitoring: Regular health and safety inspections recommended in workplace
Appearance: White to off-white crystalline powder
Odor: Weak, phenolic character
Odor Threshold: Not available
pH: 5.5–7.0 (in water, 1% solution)
Melting Point: 82–86 °C
Boiling Point: Decomposes before boiling
Flash Point: >150 °C (closed cup)
Evaporation Rate: Negligible (solid)
Flammability: Not classified as flammable material
Vapor Pressure: Very low at 20 °C
Vapor Density: Not applicable
Relative Density: 1.32 g/cm³
Solubility in Water: Slightly soluble
Solubility in Other Solvents: Soluble in some organic solvents (e.g., ethanol, acetone)
Partition Coefficient (Log Kow): 1.7–2.0
Decomposition Temperature: >200 °C
Viscosity: Not applicable (solid)
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: May react slowly with strong oxidizers or strong acids
Conditions to Avoid: Excessive heat, direct sunlight, moisture, exposure to incompatible substances
Hazardous Decomposition Products: Hydrogen chloride, phenolic compounds, carbon monoxide, carbon dioxide
Polymerization: No hazardous polymerization expected
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral/rat LD50 estimated at 1200 mg/kg
Skin Corrosion/Irritation: May cause mild to moderate irritation, especially with prolonged contact
Eye Damage/Irritation: Can produce pain, redness, watering if exposed directly
Respiratory Sensitization: Not classified, but dust can cause irritation in sensitive individuals
Skin Sensitization: Prolonged or repeated exposure may cause allergic reactions
Chronic Effects: Dermatitis, potential liver and kidney stress noted in some animal studies
Carcinogenicity: Not considered carcinogenic by NTP, IARC, OSHA
Mutagenicity: Animal studies do not show genotoxic effects
Reproductive Toxicity: No conclusive data on reproductive harm
Ecotoxicity: Potentially toxic to aquatic life with long-lasting effects if released in sufficient quantity
Persistence and Degradability: Moderately persistent, expected to degrade slowly in soil or water
Bioaccumulative Potential: May accumulate in aquatic organisms due to moderate log Kow
Mobility in Soil: Low to moderate mobility
Other Adverse Effects: Avoid release to natural waters, especially streams and lakes, due to possible harmful effects
Waste Disposal Methods: Collect and containerize solid waste for chemical incineration or disposal at licensed hazardous waste facility
Contaminated Packaging: Decontaminate and recycle if possible, otherwise treat as hazardous waste
Disposal Restrictions: Do not discharge into sewers, surface water, or soil
Local Regulations: Follow national and local guidelines for disposal, including notification to regulatory authorities if needed
UN Number: Not assigned under current transport legislations
Proper Shipping Name: Chemical, NOI (not otherwise indexed)
Transport Hazard Class: Non-regulated
Packing Group: Not regulated
Environmental Hazards: Not classed as marine pollutant
Special Precautions: Protect from moisture, heat, and strong oxidizers during transport
Transport Label: None required for ground, air, or sea shipment under current guidance
TSCA Inventory: Listed
REACH Status: Registration or notification may be required for import or use in Europe
OSHA Hazard Communication: This material is hazardous
SARA/EPCRA: No sections 302, 304, or 313 reporting required
California Proposition 65: Not listed
WHMIS Classification: D2B (Toxic material causing other toxic effects)
Other Applicable Regulations: Restrictions apply for discharge, emissions, and disposal in several jurisdictions
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