Product Name: 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate
SYNONYMS: Not established in public literature
CAS Number: Confidential or not publicly available
Recommended Use: Pharmaceutical intermediate, research chemical
Supplier: Manufacturer’s name and address, contact numbers for emergencies
Emergency phone: 24-hour chemical emergency line from supplier
Classification: Possible Acute Toxicity (Oral, Dermal, Inhalation)
GHS Label Elements: Signal word: DANGER
Pictogram: Skull and crossbones, exclamation point, health hazard
Hazard Statements: Suspected carcinogen, toxic if swallowed, may cause organ damage with repeated exposures, causes skin and eye irritation
Precautionary Statements: Wash exposed skin thoroughly, wear personal protective gear, avoid breathing dust/vapors, keep container tightly sealed
Other Hazards: May be harmful to aquatic life with long lasting effects
Specific Target Organ Toxicity: Data limited, consult latest toxicological reports for updates
Chemical: 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate
Concentration: 100% (pure substance or clearly indicate dilution)
Impurities: Not specifically listed, may contain related analogs below 1%
Molecular Formula: C45H54F2N4O8 • C4H6O6
Molecular Weight: Supplier-specified upon analysis
General: Move affected individual from exposure area immediately
Inhalation: Bring person outdoors for fresh air, support breathing, give oxygen if difficult to breathe, seek medical advice
Skin Contact: Remove contaminated clothing, flush skin with water for at least 15 minutes using a safety shower, contact physician
Eye Contact: Rinse eyes with water cautiously for over 15 minutes; lift eyelids occasionally, consult an eye specialist promptly
Ingestion: Rinse mouth, never induce vomiting, offer water only if person is alert, seek toxicological evaluation right away
Medical Information: Treat symptomatically, provide poison control with product information
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, water spray, or foam for fires involving this substance
Unsuitable Extinguishing Media: Direct high-pressure water jets may scatter material
Hazards from Combustion: Produces toxic fumes like carbon oxides, nitrogen oxides, hydrogen fluoride, possible corrosive vapors
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Protective Actions: Move containers from the area if safe, cool with water spray from a distance to prevent pressure build-up
Personal Precautions: Evacuate non-essential personnel, avoid dust formation, ventilate confined areas, wear splash-proof goggles, gloves, lab coat or coveralls, and approved respirator
Environmental Precautions: Prevent material from entering drains, waterways, or soil
Clean-up Methods: Sweep or shovel up into suitable disposal containers, decontaminate area with appropriate cleaning agents, incinerate or treat as hazardous waste under local regulations
Decontamination: Rinse spill area thoroughly, monitor for residue, dispose of absorbent properly
Safe Handling: Avoid contact with skin, eyes, and clothing, work in a certified fume hood, minimize dust generation, keep away from food and beverages
Storage Conditions: Store in tightly closed, labeled container in a cool, dry place, away from incompatible substances such as strong acids, bases, oxidizing or reducing agents
Incompatibilities: Strong oxidizers, reducing agents, reactive metals
Procedures: Lock storage locations, limit access to authorized personnel, keep inventory records for regulatory compliance
Engineering Controls: Use local exhaust or general laboratory ventilation, install eyewash stations and safety showers
Exposure Limits: Supplier or jurisdictional occupational exposure limits not established, use the lowest feasible exposure
Eye Protection: Safety goggles, face shields suggested in high exposure phases
Hand Protection: Chemically resistant gloves (such as neoprene, nitrile, or latex)
Skin Protection: Long-sleeved laboratory gear, chemical-resistant boots
Respiratory Protection: Certified respirator (NIOSH or EN approved) during handling of powders or large quantities
Physical State: Off-white to yellowish powder
Odor: No significant odor reported
Odor Threshold: Not determined
pH: Not applicable for dry powder
Melting/Freezing Point: Exact value supplier-specific, usually decomposes at elevated temperatures
Boiling Point: Data not available
Solubility: Soluble in water and organic solvents such as DMSO
Partition coefficient: Not experimentally determined
Vapor Pressure: Not applicable, negligible volatility
Evaporation Rate: Not relevant to powder chemical
Flash Point: Not applicable for a solid
Flammability: Not readily flammable, careful with static discharge
Density: Value varies, supplier provides specification upon request
Viscosity: Not applicable for solids
Decomposition Temp: Substance may decompose before boiling
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not known to be highly reactive at room temperature
Conditions to Avoid: Prolonged exposure to light, moisture, incompatible chemicals, excessive heat
Incompatible Materials: Strong oxidizers, strong acids or bases, organic peroxides
Hazardous Decomposition Products: Carbon oxides, fluorinated gases, nitrogen oxides under fire or decomposition conditions
Polymerization: Not expected to occur
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Acute Toxicity: Harmful in contact with skin or if swallowed, may cause serious damage to health
Chronic Effects: Potential carcinogen, repeat exposure may affect bone marrow, endocrine system, nervous and reproductive system
Skin/Eye Contact: Causes moderate-to-severe irritation
Sensitization: Repeated exposure may cause allergic reactions
Mutagenicity and Carcinogenicity: Structure-based prediction suggests possible genotoxic and carcinogenic risks
Reproductive Toxicity: Related compounds linked to reproductive toxicity, more evidence needed
Aquatic Toxicity: Harmful to aquatic organisms, may cause long-term adverse effects
Persistence/Degradability: Not readily biodegradable, persistence expected in the environment
Bioaccumulative Potential: Could accumulate in aquatic life tissues due to poor solubility in water
Mobility in soil: Tends to bind, low leaching expected; significant events may impact surface water
Other adverse effects: Potential risk to broader ecosystem if spilled in large quantities, stick to environmental monitoring protocols during use and disposal
Disposal Methods: Dispose of as hazardous chemical and pharmaceutical waste
Incineration: Preferred method with flue gas scrubbing
Do not: Release to environment, flush into sewer, mix with normal commercial or household waste
RCRA Status: May qualify as hazardous waste; comply with local, state, and federal regulations
Container Disposal: Triple rinse before disposing; puncture, crush, or incinerate containers following site practice
UN Number: Obtain correct number based on latest hazardous chemicals directory
Proper Shipping Name: Consult current IATA, DOT, or IMDG standards
Transport Hazard Class: 6.1 (Toxic substances) if classified
Packing Group: II or III depending on quantities and purity, consult transport regulations
Labels: Toxic, environmentally hazardous substance symbol
Marine Pollutant: Likely, based on structural analog data, label for transport accordingly
Special precautions: Limit quantities, use secure secondary containment, notify carriers of hazardous nature
Safety, Health and Environmental Regulations: Subject to local, national, and international chemical and pharmaceutical controls
OSHA: Not listed with a PEL, treat with best laboratory safety practices
TSCA Status: Research chemicals often not listed for commercial use
SARA Title III: Not specifically listed, possible reporting subject under Section 313 for toxic releases
REACH: May not be registered; confirm with manufacturer; use for R&D under exemption, not for direct commercial use
Other Inventory Lists: May require notification or restricted use under various country guidelines
Section 16: Review up-to-date regulatory advice from supplier; always check national requirements before lab or production use
Providing high-quality chemical products and logistics solutions for global trade partners.
