Product Name: 2-Propenoic acid, 2-methyl-, monoester with 1,2-propanediol
Synonyms: Hydroxypropyl Methacrylate (HPMA); 2-Hydroxypropyl methacrylate
CAS Number: 27813-02-1
Recommended Uses: Used in production of resins and polymers, paints, coatings, adhesives, sealants
Supplier Information: Manufacturer's name, address, phone number, and emergency contact provided per shipment
Emergency Number: Chemtrec or local emergency response service
Restrictions on Use: Not intended for personal use, not for food, drug, or cosmetic purposes
GHS Classification: Skin Irritant (Category 2), Eye Irritant (Category 2A), Sensitizer (Category 1), Specific Target Organ Toxicity - Single Exposure (Category 3)
Label Elements: Pictograms include exclamation mark, signal word: Warning
Hazard Statements: Causes skin and eye irritation, may cause allergic skin reaction, may cause respiratory irritation
Precautionary Statements: Wear protective clothing and eyewear; avoid inhalation or skin contact; wash hands after handling
Routes of Exposure: Inhalation, dermal, ocular exposure
Chemical Name: 2-Propenoic acid, 2-methyl-, monoester with 1,2-propanediol
Common Name: Hydroxypropyl methacrylate
CAS No: 27813-02-1
Concentration: 97-100% in commercial materials
Impurities: Often traces of methacrylic acid (CAS 79-41-4, <2%), inhibitors like MEHQ (monomethyl ether hydroquinone, <500 ppm)
Inhalation: Move person to fresh air; keep at rest; seek medical attention if symptoms persist, such as coughing, dizziness, throat irritation
Skin Contact: Remove contaminated clothing; rinse skin with plenty of water for at least 15 minutes; wash with soap; seek medical attention if discomfort or irritation appears
Eye Contact: Rinse eyes gently with water for at least 15 minutes, lifting eyelids occasionally; remove contact lenses if present and easy to do; seek medical attention
Ingestion: Rinse mouth thoroughly, do not induce vomiting unless instructed by medical professionals; give water if subject is conscious; seek immediate medical advice
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Direct water stream can spread spilled liquid
Specific Hazards: Vapors may form explosive mixtures with air, substance can polymerize exothermically in fire conditions
Fire-Fighting Procedures: Wear self-contained breathing apparatus and protective gear; use water to keep containers cool; avoid inhalation of fumes
Combustion Products: Carbon oxides, irritating organic vapors possible during fire conditions
Personal Precautions: Evacuate non-essential personnel; use personal protective equipment including gloves, chemical splash goggles, and respirator if significant vapor present
Environmental Precautions: Prevent entry into sewers, waterways, or soil
Containment Methods: Stop leak if safe to do; contain with sand, earth, or absorbent material
Cleanup Methods: Collect spilled material in suitable container for disposal; clean residue with detergent and ample water
Airborne Vapors: Use ventilated area, avoid breathing vapors during cleanup
Handling: Handle in well-ventilated areas, keep containers tightly closed, avoid inhalation and direct contact with skin or eyes, employ local exhaust ventilation
Storage Requirements: Store away from sunlight, heat sources, oxidizers, and acids; maintain temperature below 30°C; use containers lined with corrosion-resistant coatings
Inhibitor Requirements: Product usually stabilized with MEHQ to prevent polymerization; absence of inhibitor leads to rapid polymer buildup
Other Precautions: Ground and bond containers during transfer to prevent static discharge
Exposure Limits: No specific OSHA or ACGIH limits set for hydroxypropyl methacrylate; workplace exposure as low as reasonably achievable
Engineering Controls: Use local exhaust ventilation; closed systems reduce vapor exposure
Personal Protective Equipment: Chemical resistant gloves (nitrile or butyl), splash protective goggles, impervious clothing
Respiratory Protection: Use NIOSH-approved organic vapor respirator in case of inadequate ventilation
Hygiene: Wash hands before eating, drinking, smoking; take off contaminated clothing and wash before reuse
Physical State: Liquid
Color: Clear, colorless to slightly yellow
Odor: Mild, sweet ester odor
Melting Point: -58°C (-72°F)
Boiling Point: 213°C (415°F)
Flash Point: 98°C (208°F) closed cup
Evaporation Rate: Slower than ether
Flammability: Combustible liquid
Vapor Pressure: 0.05 mmHg at 20°C
Vapor Density: 5.9 (air = 1)
Relative Density: 1.08 g/cm³ at 20°C
Solubility: Miscible with water
Partition Coefficient (Log Kow): 0.97
Auto-ignition Temperature: 348°C (658°F)
Decomposition Temperature: Not specified
Viscosity: 6.0 mPa·s at 25°C
Chemical Stability: Stable under recommended storage, sensitive to heat, light, and peroxides
Reactivity: Reacts vigorously with strong acids, bases, oxidizers; exothermic polymerization possible with heat or contamination
Incompatible Materials: Peroxides, free radical initiators, strong acids/bases, oxidizers, heavy metal salts
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, methyl methacrylate monomers, formaldehyde on combustion
Polymerization: May occur if not stabilized; sudden polymerization causes pressure rise in closed containers
Acute Toxicity: Inhalation LC50 (rat, 4h) >5 mg/l; oral LD50 (rat) 5180 mg/kg; dermal LD50 (rabbit) >3000 mg/kg
Skin Irritation: Causes moderate to severe skin irritation, burns possible with long exposure
Eye Irritation: Strong irritant, risk of serious damage
Sensitization: Skin sensitizer; repeated or prolonged contact increases risk
Chronic Exposure: May cause dermatitis, allergic reactions
Other Health Effects: Inhalation of vapors may cause headaches, dizziness, respiratory tract irritation
Carcinogenicity: No components considered carcinogenic by IARC, NTP, OSHA
Mutagenicity: Not classified as mutagenic based on existing data
Ecotoxicity: Fish LC50 (96 h, Pimephales promelas) 493 mg/L; Daphnia EC50 (48 h) 380 mg/L; low to moderate toxicity to aquatic life
Persistence and Degradability: Readily biodegradable (68% in 28 days, OECD 301C)
Bioaccumulative Potential: Low, Log Kow near zero suggests little accumulation
Mobility in Soil: Highly mobile; can contaminate groundwater if released in significant volume
Other Adverse Effects: Avoid large releases, not classified as marine pollutant but can upset local ecosystem balance
Waste Disposal: Dispose of as hazardous waste according to local regulations; incineration recommended if permitted
Contaminated Packaging: Rinse packaging with solvent, dispose as hazardous waste
Precautions: Do not allow material to enter public water systems; seek professional advice on disposal options
UN Number: UN 1993
UN Proper Shipping Name: Flammable liquids, n.o.s. (contains hydroxypropyl methacrylate)
Transport Hazard Class: 3 (flammable liquid)
Packing Group: III
Environmental Hazards: Not listed as marine pollutant
Special Precautions: Tight containers recommended, clearly labeled, keep away from incompatible materials, ensure temperature control during transit
TSCA: Listed in US TSCA Inventory
DSL (Canada): Present on Domestic Substances List
REACH (EU): Registered substance under REACH
OSHA Hazards: Skin sensitizer, irritant
SARA Title III: Not subject to Section 313 reporting
State Regulations: California Proposition 65: Not listed
WHMIS Classification: D2B (toxic materials causing other chronic effects)
Other Country Regulations: Check local lawful requirements for further restrictions or information
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