Material Safety Data Sheet for 2-Nitro-2-bromo-1,3-propanediol

Identification

Product Name: 2-Nitro-2-bromo-1,3-propanediol
Synonyms: Bronopol, 2-Bromo-2-nitropropane-1,3-diol
CAS Number: 52-51-7
Recommended Use: Used as a preservative and antimicrobial agent in industrial applications
Manufacturer: Refer to supplier information on packaging
Contact Information: Emergency: Local poison center or emergency response number on label
Email for SDS Requests: Provided by supplier

Hazard Identification

Classification: Acute toxicity (oral, dermal, inhalation), skin irritation, eye irritation, aquatic acute/chronic hazard
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause allergic skin reaction, very toxic to aquatic life with long lasting effects
Pictograms: Exclamation mark, Environment
Signal Word: Warning
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, avoid release to environment, use personal protective equipment as required
Other Hazards: May decompose under fire conditions releasing toxic gases; use only in well-ventilated areas

Composition / Information on Ingredients

Chemical Name: 2-Nitro-2-bromo-1,3-propanediol
CAS Number: 52-51-7
Concentration: At least 98% by weight in pure chemical form
Impurities: Trace amounts of related organic compounds
Molecular Formula: C3H6BrNO4
Molecular Weight: 199 g/mol

First Aid Measures

Inhalation: Remove to fresh air immediately, maintain breathing and seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash with plenty of soap and water; seek medical advice if irritation continues
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek urgent medical care
Symptoms: May include irritation, redness, allergic reactions, shortness of breath, nausea
Advice to Physician: Symptomatic treatment based on clinical assessment

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Special Hazards: Decomposition yields toxic fumes (nitrogen oxides, bromine, hydrogen bromide)
Firefighter Protection: Full protective clothing and self-contained breathing apparatus
Additional Information: Cool containers with water from a safe distance; prevent runoff from entering water sources

Accidental Release Measures

Spill Response: Evacuate area, ventilate, use appropriate personal protective equipment
Cleanup Procedures: Absorb with inert material (such as sand), collect in properly labeled containers
Environmental Precautions: Prevent entry to sewers and waterways, notify authorities if product contaminates environment
Disposal: Dispose of in accordance with local, regional, and national regulations

Handling and Storage

Precautions: Handle with care to avoid spills or exposure, avoid inhalation and contact with skin or eyes
Storage Conditions: Store in original container in cool, dry, well-ventilated area away from direct sunlight and sources of heat or ignition
Segregation: Keep away from incompatible substances such as strong oxidizers, reducing agents, acids
Additional Guidance: Keep containers tightly closed and labeled; only trained personnel should handle

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for this compound; use workplace hygiene standards for control
Engineering Controls: Use local exhaust ventilation to minimize exposure, especially in confined spaces
Personal Protective Equipment (PPE): Chemical-resistant gloves, safety glasses or goggles, lab coats or aprons, approved respirator in case of insufficient ventilation
Additional Requirements: Emergency eyewash fountains and safety showers should be accessible

Physical and Chemical Properties

Appearance: White to off-white crystalline solid
Odor: Faint chemical odor
Melting Point: 130 to 135°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, glycols
Vapor Pressure: Low at room temperature
pH: Neutral to slightly acidic in water
Density: 2.0 g/cm³
Flash Point: Not flammable
Other Information: Stable under recommended conditions, corrosive toward some metals under moist conditions

Stability and Reactivity

Chemical Stability: Remains stable under normal conditions of handling and storage
Reactive With: Strong oxidizing agents, reducing agents, acids and bases can trigger hazardous decomposition
Hazardous Decomposition: Bromine, hydrogen bromide, nitrogen oxides released if heated or combusted
Polymerization: Not expected under normal handling but avoid contaminating substances
Conditions to Avoid: Heat, flames, direct sunlight, moisture, incompatible materials

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): 305 mg/kg, Dermal LD50 (rat): 1600 mg/kg
Effects: Irritation to skin, eyes, and respiratory tract; potential to cause allergic skin reactions
Chronic Exposure: Prolonged or repeated contact may cause dermatitis, sensitization
Carcinogenicity: No data indicating carcinogenicity in humans
Mutagenicity/Teratogenicity: Some laboratory evidence suggests possibility of genotoxic effects
Other Data: No effects on reproductive health observed at typical exposure levels in industry

Ecological Information

Toxicity: Highly toxic to aquatic organisms, LC50 (fish, 96 h): 1.8 mg/L
Persistence and Degradability: Not readily biodegradable based on available data
Potential Bioaccumulation: Low bioaccumulation potential
Mobility: Expected to have moderate mobility in soil and water environments
Other Ecological Effects: May cause long-term adverse effects in the aquatic environment; use best practices to contain and collect spills

Disposal Considerations

Waste Treatment Methods: Chemical must be disposed as hazardous waste
Incineration: Suitable in a properly permitted facility where emissions can be controlled
Landfill: Only if fully compliant with local regulations governing hazardous chemical disposal
Special Precautions: Do not flush product or residues to drains, surface waters, or soil
Container Disposal: Triple rinse and offer for reconditioning or local disposal under hazardous waste protocols

Transport Information

UN Number: 3241
Proper Shipping Name: 2-Bromo-2-nitropropane-1,3-diol
Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels Required: Toxic, Environmentally Hazardous
Special Precautions: Protect from spills and leaks, avoid transfer between unlabelled containers
Marine Pollutant: Yes, subject to additional requirements for aquatic toxicity

Regulatory Information

US Regulations: Listed on TSCA inventory, subject to SARA Title III reporting for releases, EPA-regulated for water discharges and disposal
EU Regulations: Classified hazardous under CLP Regulation (EC) No 1272/2008, subject to REACH registration, listed in Annex VI
Other International: Listed or controlled by chemical inventories in Canada, Australia, and Japan
Labeling Requirements: Supplier labels must meet GHS requirements, include hazard pictograms, statements, and emergency measures
Workplace Controls: Subject to chemical safety management, worker training, and exposure monitoring according to OSHA and EU directives