Product Name: 2-(Hydroxymethyl)-2-nitro-1,3-propanediol
Synonyms: Nitrodiol, Bronopol
CAS Number: 52-51-7
Recommended Use: Preservative, antimicrobial agent, industrial biocide
Supplier Information: Manufacturer contact details, address, telephone, emergency contact
Classification: Acute toxicity (oral, dermal), Eye irritation, Skin sensitization, Environmental hazard
Label Elements: Hazard pictograms, signal word “Warning”, hazard statements describing toxic, irritant, and sensitizing properties
Health Hazards: Causes skin and eye irritation, may cause allergic reactions, harmful if swallowed or absorbed through skin
Environmental Hazards: Very toxic to aquatic life, risk of long-term adverse effects in the aquatic environment
Precautionary Statements: Wear suitable protective equipment, avoid release to the environment, wash hands thoroughly after handling
Substance: 2-(Hydroxymethyl)-2-nitro-1,3-propanediol
Chemical Formula: C3H7NO4
Concentration: 98-100%
Impurities or Stabilizing Additives: Trace impurities may include unreacted raw materials or degradation products
Inhalation: Move victim to fresh air, keep comfortable, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin with soap and plenty of water, seek medical help for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy, seek medical attention if irritation continues
Ingestion: Rinse mouth, do not induce vomiting, call poison control or physician immediately
Most Important Symptoms: Skin redness, itching, rash, eye watering, abdominal discomfort
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Fire Hazards: May emit toxic fumes under fire conditions (nitrogen oxides, formaldehyde, carbon monoxide, carbon dioxide)
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Precautions: Avoid inhaling combustion products, use water spray to cool containers exposed to fire
Personal Precautions: Use personal protective equipment, avoid breathing dust or vapor, avoid skin and eye contact
Environmental Precautions: Prevent entry to sewers, surface or ground water, contain spill using inert material
Methods for Cleanup: Scoop or sweep spilled material into appropriate waste containers for disposal, ventilate area thoroughly, clean contaminated surface with water and detergent, avoid generating dust
Precautions for Safe Handling: Only handle in well-ventilated areas, avoid dust formation, keep away from flame and heat sources, do not eat, drink or smoke near product
Conditions for Safe Storage: Store tightly closed in a cool, dry, well-ventilated place, protect from sunlight and moisture, keep away from incompatible substances such as strong acids, bases, reducing agents
Engineering Controls: Use local exhaust ventilation or other engineering controls to maintain airborne levels below recommended exposure limits
Personal Protective Equipment (PPE): Chemical-resistant gloves, safety goggles, lab coat, respiratory protection if ventilation is inadequate
Hygiene Measures: Wash hands, forearms, and face after handling, change contaminated clothing, prevent contact with skin, eyes, and clothing
Appearance: White crystalline powder
Odor: Slight, characteristic odor
pH: ~5.0 (25°C, 1% solution)
Melting Point: 130–132°C
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water
Vapor Pressure: Not applicable at ambient temperature
Density: Approx. 1.68 g/cm³
Partition Coefficient: log Kow −0.64
Other Properties: Stable under standard conditions, may yellow upon long-term exposure to air or heat
Chemical Stability: Stable at room temperature under normal storage and use
Incompatible Materials: Strong acids, strong bases, strong reducing agents
Decomposition Products: Nitrogen oxides, formaldehyde, carbon monoxide, carbon dioxide
Hazardous Reactions: Risk of hazardous polymerization or decomposition under heat or incompatible conditions
Acute Toxicity: Oral LD50 (rat): 180–200 mg/kg, Dermal LD50 (rabbit): >1000 mg/kg
Skin Corrosion/Irritation: Causes mild to moderate irritation
Serious Eye Damage/Irritation: Causes eye irritation, possible corneal damage
Respiratory Sensitization: May cause respiratory irritation if inhaled
Skin Sensitization: Known to cause allergic contact dermatitis
Mutagenicity: Evidence points to weak mutagenic potential in vitro; in vivo evidence limited
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Long-term Effects: Repeated or prolonged exposure may result in skin sensitization or chronic dermatitis
Ecotoxicity: Highly toxic to aquatic organisms, LC50 (fish, 96h): 1.8 mg/L, EC50 (daphnia, 48h): 1.4 mg/L, EC50 (algae, 72h): 0.4–1.8 mg/L
Persistence and Degradability: Biodegradable under aerobic conditions, but may persist in some environmental compartments
Bioaccumulative Potential: Low, due to low log Kow value and water solubility
Mobility in Soil: High, will leach readily to ground water due to high solubility
Other Adverse Effects: Possible negative impact on micro-organisms used in wastewater treatment
Waste Treatment Methods: Incinerate in approved facility for hazardous chemical waste, or dispose of in accordance with local, state, and federal regulations
Contaminated Packaging: Empty containers must be handled with care, triple rinse, and dispose as hazardous waste
Precautions for Disposal: Avoid discharge into drains, surface or ground water, do not dispose into the environment
UN Number: UN 2811
Shipping Name: Toxic solid, organic, n.o.s. (2-(Hydroxymethyl)-2-nitro-1,3-propanediol)
Transport Hazard Class: 6.1 Toxic substances
Packing Group: III
Hazard Label: Toxic
Environmental Hazards: Marine pollutant
Special Precautions: Transport in accordance with national and international regulations, ensure packaging prevents release and exposure
OSHA Status: Regulated hazardous chemical
TSCA Inventory: Listed
EU REACH Status: Registered, subject to restrictions for biocidal uses
DSL/NDSL (Canada): Listed
Risk Phrases: Harmful if swallowed, irritating to eyes and skin, may cause sensitization by skin contact
Safety Phrases: Keep locked up and out of reach of children, avoid contact with skin and eyes, in case of accident or if you feel unwell, seek medical advice
Other National and International Regulations: Covered by national regulations for handling hazardous chemicals and biocides, subject to labeling and hazard communication standards
Providing high-quality chemical products and logistics solutions for global trade partners.
