Product Name: 2-Bromo-2-nitro-1,3-propanediol
Common Names: Bronopol
CAS Number: 52-51-7
Relevant Uses: Antimicrobial preservative in cosmetics, personal care products, industrial water systems, and cooling fluids
Supplier Details: Manufacturer or distributor contact info as provided on shipping label and invoice
Emergency Phone: Refer to the local poison control center or supplier emergency line
GHS Classification: Acute toxicity, oral (Category 4), eye irritation (Category 2A), skin irritation (Category 2), aquatic acute toxicity (Category 1), aquatic chronic toxicity (Category 1)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, very toxic to aquatic life with long-lasting effects
Pictogram: Exclamation mark, Environment
Precautionary Statements: Wash hands thoroughly after handling. Avoid release into the environment. Wear protective gloves, clothing, and eye protection.
Chemical Name: 2-Bromo-2-nitropropane-1,3-diol
CAS Number: 52-51-7
EC Number: 200-143-0
Purity: Typically >99%
Impurities: Trace levels of related bromonitro compounds, water (<1%)
Other Components: None or not present in hazardous concentrations
General Measures: Move to fresh air, remove contaminated clothing, seek medical advice immediately
Inhalation: Remove victim from source, provide oxygen if breathing is difficult
Skin Contact: Wash with plenty of water for at least 15 minutes, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, obtain medical attention
Ingestion: Rinse mouth, do not induce vomiting, get medical attention promptly
Most Important Symptoms: Redness, irritation, possible burns to eyes or skin, respiratory discomfort, nausea
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, foam, water spray
Unsuitable Media: Direct water jet can spread the product
Special Hazards: Product can decompose to release toxic gases such as hydrogen bromide, nitrogen oxides, formaldehyde, and carbon oxides
Protective Equipment: Full protective clothing, self-contained breathing apparatus
Specific Procedures: Remain upwind, cool nearby containers with water spray
Combustion Products: Hydrogen bromide, oxides of nitrogen, carbon monoxide, carbon dioxide
Personal Precautions: Evacuate unnecessary personnel, provide adequate ventilation, avoid dust formation
Protective Equipment: Chemical-resistant gloves, goggles, protective clothing, respirator recommended
Environmental Precautions: Prevent entry into drains and waterways, dike for later disposal
Methods for Cleaning Up: Sweep or scoop spilled material into suitable container; avoid creating dust, clean spill site with water and detergent
Safety Measures: Avoid contact with skin, eyes, and clothing, do not breathe dust or vapors
Handling: Use only in a well-ventilated area, handle with appropriate PPE, wash thoroughly after handling
Storage Conditions: Store in a tightly closed original container, keep in a cool, dry, well-ventilated area away from moisture, heat, and direct light
Incompatible Materials: Strong acids, alkalis, oxidizing agents, reducing agents, amines
Specific Storage Requirements: Keep separate from food and feed, limit access to trained personnel
Occupational Exposure Limits: No established threshold limit value (TLV); minimize exposure
Engineering Controls: Local exhaust ventilation, general room ventilation
Personal Protection: Nitrile gloves, chemical goggles or face shield, lab coat or apron, respiratory protection in case of dust or insufficient ventilation
Hygiene Measures: Wash hands before eating, drinking, or smoking, remove contaminated clothing and wash before reuse
Appearance: White to off-white crystalline powder
Odor: Faint, characteristic
Melting Point: 130–134 °C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water (25 g/L at 20 °C)
Vapor Pressure: Negligible at room temperature
Density: 1.9 g/cm³
pH: 6.0–7.0 (1% solution)
Partition Coefficient (log Kow): -0.64
Other Data: Stable under recommended storage conditions, decomposes on heating or exposure to sunlight
Chemical Stability: Stable at room temperature, degrades under heat/humidity
Reactivity: May react with strong reducing agents, strong acids or bases, amines
Hazardous Reactions: Decomposition releases toxic gases such as nitrogen oxides, hydrogen bromide
Polymerization: Not expected to occur
Conditions to Avoid: Moisture, elevated temperatures, exposure to direct light or incompatible compounds
Incompatible Materials: Strong bases, acids, reductants, oxidizers, amines
Acute Toxicity (Oral): LD50 (rat): 305 mg/kg
Acute Toxicity (Dermal): LD50 (rabbit): 2000 mg/kg
Skin Irritation: Causes skin irritation, redness, discomfort possible
Eye Irritation: Causes serious eye irritation, pain, redness, blurred vision
Respiratory Effects: Dust causes irritation of respiratory tract
Sensitization: Skin sensitizer in susceptible individuals
Chronic Effects: Repeated exposure may cause allergic skin reactions
Mutagenicity: Animal or human data show possible mutagenic effects
Carcinogenicity: Not classified as carcinogenic by IARC, OSHA, NTP, or ACGIH
Reproductive Toxicity: Insufficient data available
Other Effects: No specific information for teratogenicity, chronic neurotoxicity
Toxicity to Aquatic Life: Extremely toxic to aquatic organisms (LC50 fish 1.4 mg/L, EC50 daphnia 0.9 mg/L, 48 hr)
Persistence and Degradability: Moderately persistent, hydrolyzes in water, breaks down in sunlight
Bioaccumulative Potential: Low; does not significantly accumulate in aquatic organisms (log Kow low)
Mobility in Soil: Mobile, can leach into groundwater under certain conditions
Other Adverse Effects: Even small releases can harm aquatic plants and animals; long-lasting effects in water systems
Safe Disposal: Collect and place in suitable containers for incineration or in accordance with local regulations
Waste Codes: Assign appropriate EPA or regional waste codes as per guidelines
Contaminated Packaging: Rinse and dispose as hazardous waste, do not reuse empty containers
Environmental Release: Prevent product from entering watercourses or sewer system, consult local authority on disposal methods
UN Number: 3241
Proper Shipping Name: 2-Bromo-2-nitropropane-1,3-diol
Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Yes
Transport Labels: Toxic, Environmentally Hazardous
Special Precautions: Provide adequate ventilation, avoid damage to packaging that could release contents
Additional Transport Information: Handle and stow away from food, feed, and incompatible chemicals
TSCA: Listed
DSL/NDSL (Canada): Listed
EU REACH: Substance registered, subject to restrictions
OSHA: Hazardous chemical as defined in Hazard Communication Standard 29 CFR 1910.1200
WHMIS (Canada): Classified as toxic and environmentally hazardous
Labeling Requirements: GHS compliant, with appropriate pictograms and hazard statements
Other Regulations: Subject to regulations for workplace exposure, environmental release, and disposal; local, state and national rules may require additional measures
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