Product Name: 2-Bromo-2-Nitro-1,3-Propanediol
Synonyms: Bronopol; Brominol; Myacide; BNPD
CAS Number: 52-51-7
Recommended Use: Used as a preservative and antimicrobial agent in cosmetics, personal care products, and some industrial applications
Supplier Details: Chemical manufacturer’s contact on file for emergencies and technical support
Emergency Phone: Accessible through Chemtrec, local poison control, or manufacturer emergency line
GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye damage, Aquatic hazard
Hazard Pictograms: Skull and crossbones, Exclamation mark, Corrosive, Environment
Signal Word: Danger
Hazard Statements: Harmful if swallowed or inhaled; Causes skin irritation; Causes serious eye damage; May cause allergic skin reaction
Precautionary Statements: Wear gloves, protective eyewear, and a mask; Wash hands after handling; Avoid breathing dust, vapors, or spray; Prevent release to the environment
Routes of Entry: Skin contact, eye contact, inhalation, ingestion
Chemical Name: 2-Bromo-2-Nitro-1,3-Propanediol
Concentration: 99%+ (purity depends on source)
CAS Number: 52-51-7
Impurities and Stabilizing Additives: Minor unreacted precursors or solvents, sometimes present below 1%
Inhalation: Move the person to fresh air promptly. Provide warmth and rest. Seek medical attention for breathing difficulty, coughing, or irritation.
Skin Contact: Remove contaminated clothing. Rinse skin with water for at least 15 minutes. If irritation persists or rash develops, get medical advice.
Eye Contact: Immediately rinse with plenty of water for no less than 15 minutes, forcing eyelids open. Remove contact lenses if present and easy to do. Immediate medical attention is needed.
Ingestion: If swallowed, rinse mouth with water. Do not induce vomiting. Obtain medical attention and show product label if available.
Most Important Symptoms: Skin rash, eye burns, throat irritation, shortness of breath
Notes for Doctor: Treat symptomatically, monitor for delayed allergic reactions or bronchospasm
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide. Water jet may spread product.
Hazards from Combustion Products: Releases toxic fumes including hydrogen bromide, nitrogen oxides, and carbon oxides when heated to decomposition.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing.
Special Precautions: Avoid runoff to sewers or waterways. Cool containers exposed to flames with water.
Personal Precautions: Isolate spill area. Evacuate unnecessary personnel. Wear gloves, chemical goggles, and respiratory protection.
Environmental Precautions: Prevent access to waterways, drains, and soil. Notify authorities if significant spill occurs.
Containment Methods: Absorb spill with inert material like sand or earth. Scoop up spill residue and dispose in labeled containers.
Cleanup Procedures: Use a shovel or vacuum approved for chemical spills. Ventilate area and wash spill site after cleanup.
Handling: Use only in well-ventilated areas. Avoid inhalation, ingestion, and contact with skin or eyes. Handle with care to prevent dust formation.
Storage: Store in tightly closed containers, in a cool, dry, well-ventilated location. Keep away from oxidizers, heat, sparks, and open flames. Avoid direct sunlight. Label containers clearly.
Incompatibility: Strong acids, bases, reducing agents, amines, and oxidizing agents cause hazardous reactions or degrade product stability.
Exposure Limits: No OSHA or ACGIH occupational exposure limits established
Engineering Controls: Recommended use of local exhaust ventilation, especially for large-scale or bulk handling
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat or apron, and NIOSH-approved respirator in poorly ventilated environments
Hygiene Measures: Wash hands and forearms thoroughly after work. No eating, drinking, or smoking in work area.
Appearance: White to off-white crystalline powder
Odor: Faint, characteristic odor
pH: 5.0–7.0 (1% solution in water)
Melting Point: 130–133°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, very slightly soluble in alcohol
Vapor Pressure: Low
Specific Gravity: 1.59
Partition Coefficient (log Kow): -0.64
Flash Point: Not applicable (non-flammable solid)
Chemical Stability: Stable under recommended storage conditions, but slowly decomposes in alkaline conditions
Reactivity: Reacts with strong reducing agents, acids, and bases
Hazardous Decomposition: Releases toxic fumes, including hydrogen bromide and nitrogen oxides, when heated or burned
Polymerization: Does not occur under normal conditions
Incompatible Materials: Reactive with oxidizing agents, strong bases, and reducing agents
Routes of Exposure: Skin, eye, inhalation, oral
Acute Toxicity: Oral LD50 (rat): 305 mg/kg; Dermal LD50 (rabbit): >2000 mg/kg
Corrosivity/Irritation: Causes serious eye damage and skin irritation
Serious Health Effects: May cause allergic skin reactions and respiratory irritation; not classified as carcinogenic
Sensitization: Skin sensitizer in some individuals
Chronic Effects: Prolonged exposure may damage skin, eyes, or respiratory tract
Relevant Toxicological Studies: Documented cases of contact dermatitis; limited data on long-term inhalation
Ecotoxicity: Highly toxic to aquatic life with long lasting effects
Persistence and Degradability: Slowly degrades in the environment, especially in sunlight and alkaline conditions
Bioaccumulation Potential: Low based on low log Kow
Mobility in Soil: Moderate mobility; risk of leaching to groundwater in porous soils
Other Adverse Effects: Large spills may disrupt local aquatic ecosystems and spoil water sources
Methods of Disposal: Incinerate or use approved waste contractor for chemical disposal. Follow all federal, state, and local regulations.
Waste Packaging: Triple rinse containers, puncture, and dispose as chemical waste
Precautions: Wear recommended gear, prevent environmental release during disposal, use secure labeled containers
UN Number: 3241
UN Proper Shipping Name: 2-Bromo-2-nitropropane-1,3-diol
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Secure all containers, include hazard labels, provide paperwork as required by transit authority
U.S. Regulations: Subject to TSCA and CERCLA reporting for releases; not listed as a controlled substance
EU Regulations: Covered under REACH; classified as hazardous to health and the environment
Labeling Requirements: GHS hazard symbols, signal words, and precaution statements must be shown on all packaging
Other Regulatory Lists: Appears on several national chemical inventories, including Canada DSL, Australia AICS, Japan ENCS
Workplace Restrictions: Training, hazard communication, and PPE enforcement required under OSHA or local laws
Providing high-quality chemical products and logistics solutions for global trade partners.
