MSDS for 2-(3R)-3-Piperidinyl-1H-Isoindole-1,3(2H)-Dione D-(-)-Tartarate

Identification

Product Name: 2-(3R)-3-Piperidinyl-1H-Isoindole-1,3(2H)-Dione D-(-)-Tartarate
CAS Number: Not officially assigned
Synonyms: D-(-)-Tartaric acid salt of isoindole-piperidine derivative
Recommended Use: Laboratory chemical, research and development applications
Restrictions on Use: Not for food, drug, or household use
Manufacturer Information: Refer to supplier details on packaging
Emergency Phone: Local emergency services or poison control center

Hazard Identification

Classification: Acute toxicity (oral), Skin and eye irritation, Specific target organ toxicity
Pictograms: Exclamation mark, Health hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed, May cause skin irritation, May cause eye irritation, May cause respiratory irritation
Precautionary Statements: Wear suitable gloves, protective clothing and eye protection, Avoid breathing dust or fumes, Wash hands thoroughly after handling, Do not eat, drink or smoke when using this material
Other Hazards: No reliable data on bioaccumulation or carcinogenicity, Avoid release to environment

Composition / Information on Ingredients

Chemical Identity: 2-(3R)-3-Piperidinyl-1H-Isoindole-1,3(2H)-Dione D-(-)-Tartarate
Purity: >98% (typically as supplied by laboratories)
Impurities: Not specifically identified, trace residual solvents may be present from synthesis
Molecular Formula: C15H18N2O6
Molecular Weight: Approx. 322.32 g/mol
Ingredient Range: 100% active ingredient, no significant excipients

First Aid Measures

Inhalation: Move affected person to fresh air, keep at rest, seek medical attention for respiratory distress
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, obtain medical attention for irritation
Eye Contact: Rinse cautiously with water, remove contact lenses if present and easy to do, continue rinsing, seek medical advice
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical attention immediately
Most Important Symptoms: Coughing, sneezing, redness, itching, headache, nausea possible following significant exposure
Note to Physician: Treat symptomatically, monitor for delayed respiratory or neurological effects

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical or alcohol-resistant foam
Specific Hazards: Combustion produces carbon oxides, nitrogen oxides, possible toxic fumes
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Special Procedures: Use water spray to cool adjacent containers, control run-off to avoid environmental contamination
Explosion Hazards: No data for explosive properties, standard precautions against dust buildup should be followed

Accidental Release Measures

Personal Precautions: Evacuate area, ensure adequate ventilation, use personal protective equipment
Environmental Precautions: Prevent entry into drains, waterways or soil
Spill Cleanup Methods: Sweep or vacuum up dry material without creating dust, place in appropriate waste container
Decontamination: Wash contaminated surfaces with appropriate detergent solution, ventilate area
Disposal: Dispose of residues per section on disposal considerations

Handling and Storage

Handling: Use in well-ventilated area, avoid contact with skin, eyes and clothing, prevent dust formation, wash hands after handling
Storage Conditions: Store tightly closed in original packaging, in a cool, dry, well-ventilated place, protect from moisture and direct sunlight
Incompatibilities: Keep away from strong oxidizing agents, acids and bases
Safe Transfer: Avoid spillage and minimize airborne powder

Exposure Controls and Personal Protection

Engineering Controls: Work within fume hood or similar engineering controls to limit exposure
Eye Protection: Wear safety goggles with side-shields
Skin Protection: Use chemical-resistant gloves and laboratory coat
Respiratory Protection: If risk of inhalation exists, wear NIOSH-approved dust mask or respirator
Hygiene Measures: Do not eat, drink or smoke during use, wash hands before breaks and after handling
Exposure Limits: No specific occupational exposure limit established for this material

Physical and Chemical Properties

Appearance: Powder or crystalline solid (color varies from white to off-white)
Odor: No distinct odor
Odor Threshold: Not determined
pH: Not readily applicable (insoluble in water), acidic if tartarate component dominant
Melting Point/Range: 162–170°C (estimated from available data)
Boiling Point: Decomposition before boiling
Flash Point: Not applicable
Flammability: Not easily flammable
Vapor Pressure: Negligible at room temperature
Evaporation Rate: Not applicable
Relative Density: Data not available
Solubility: Sparingly soluble in water, soluble in organic solvents such as ethanol, DMSO
Partition Coefficient (n-octanol/water): Data not determined
Auto-ignition Temperature: No data
Decomposition Temperature: Above 170°C
Viscosity: Not applicable (solid form)

Stability and Reactivity

Reactivity: No hazardous reactivity expected with normal laboratory use
Chemical Stability: Stable under recommended conditions
Possible Hazardous Reactions: Reacts with strong oxidizing agents
Conditions to Avoid: Excessive heat, exposure to moisture, strong UV or sunlight
Incompatible Materials: Strong acids, strong bases, oxidizers
Decomposition Products: Toxic fumes including carbon oxides, nitrogen oxides during fire or decomposition

Toxicological Information

Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Harmful in large quantities by ingestion; low toxicity expected at low concentration
Skin Irritation: Can cause redness and mild irritation
Eye Damage/Irritation: May cause irritation, tearing, reddening
Respiratory Sensitization: Coughing and shortness of breath reported by laboratory users after dust exposure
Inflammation and Sensitization: No sensitization data available, monitor for allergic reaction with continued exposure
Chronic Effects: No sufficient data, avoid repeated or long-term exposure
Carcinogenicity/Mutagenicity: Not listed by IARC, NTP, or OSHA
Reproductive Toxicity: No conclusive studies, as a precaution, avoid exposure during pregnancy or lactation
Other Data: Handle using recommended precautions, with medical supervision for significant exposure

Ecological Information

Ecotoxicity: Not thoroughly studied, likely low to moderate risk, avoid contamination of soil and waterways
Persistence and Degradability: Partially biodegradable, persistence possible in soil and water due to limited data
Bioaccumulation Potential: Not expected to bioaccumulate significantly
Mobility in Soil: Limited mobility expected because of low water solubility
Other Harmful Effects: Lack of sufficient ecological testing, best practice recommends proper waste management

Disposal Considerations

Disposal Methods: Dispose of in compliance with local, regional and national regulations using an authorized chemical waste contractor
Container Disposal: Rinse empty containers with suitable solvent and dispose according to regulations
Waste Classification: Not specifically listed as hazardous, treat as laboratory chemical waste
Precautions: Avoid environmental release, do not dispose of in general waste or drains
Contaminated Packaging: Triple rinse, remove or deface labels, dispose of by incineration or as required locally

Transport Information

UN Number: Not regulated for ground or air transport under standard chemical shipment guidelines
UN Proper Shipping Name: Not applicable
Transport Hazard Class: N/A
Packing Group: N/A
Marine Pollutant: Not expected
Special Precautions: Ship securely in leakproof packaging, ensure all documentation is supplied, restrict access to trained personnel

Regulatory Information

OSHA Status: Not classified as hazardous under OSHA Hazard Communication Standard
TSCA: May not be listed on US TSCA Inventory
SARA 311/312 Hazards: Acute toxicity, irritant
California Proposition 65: Not on list of chemicals known to State of California to cause cancer or reproductive toxicity
REACH Status (EU): Research use only, not registered for commercial use
Other National Regulations: Compliance required with applicable local, state, and federal health and safety regulations
Label Requirements: Appropriate hazard pictograms and precautionary statements under GHS