Product Name: 2-[3(S)-[3-[2-(7-Chloroquinoline-2-Yl)Ethenyl]Phenyl]-3-Hydroxypropyl]Benzene-2-Propanol
Synonyms: 7-Chloroquinoline vinyl hydroxyphenyl propyl benzenepropanol
Recommended Uses: Laboratory research, chemical synthesis
Manufacturer Information: Refer to supplier or distributor’s address and contact numbers for details on commercial or emergency assistance.
Emergency Contact Number: ChemTrec, local poison control, or internal safety personnel, available 24/7 for hazardous exposure or spills.
GHS Classification: Acute toxicity (oral and dermal), Skin irritation, Eye irritation, Specific target organ toxicity
Label Elements: Pictograms covering acute toxicity, skin and eye irritant warnings. Signal Word: Danger
Hazard Statements: Harmful if swallowed or absorbed through skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory tract irritation upon inhalation.
Precautionary Statements: Wear protective gloves, eye protection, and lab coats; prevent inhalation and ingestion; wash hands thoroughly after handling.
Other Hazards: Combustible dust formation if handled in powder form. Chemical may cause sensitization on repeated contact.
Chemical Name: 2-[3(S)-[3-[2-(7-Chloroquinoline-2-Yl)Ethenyl]Phenyl]-3-Hydroxypropyl]Benzene-2-Propanol
CAS Number: 136977-58-1 (example; confirm as per source material)
Concentration: >98% pure substance
Impurities & Stabilizing Additives: May contain trace solvents, unreacted starting materials, manufacturing byproducts. Refer to certificate of analysis for impurity profile.
Inhalation: Move person to fresh air immediately, provide oxygen if breathing is difficult. Seek immediate medical attention if coughing, wheezing, or respiratory symptoms occur.
Skin Contact: Remove contaminated clothing. Rinse affected skin with copious amounts of water and mild soap for at least 15 minutes. If irritation persists, seek medical assessment.
Eye Contact: Flush eyes with running water for minimum 15 minutes, holding eyelids apart. Remove contact lenses if present and easy to do. Medical evaluation recommended.
Ingestion: Rinse mouth thoroughly, avoid forceful vomiting. Observe for symptoms such as abdominal pain, nausea, or dizziness. Obtain immediate medical help for further evaluation.
Most Important Symptoms: Irritation, chemical burns, allergic response. Complications more severe with pre-existing skin or respiratory conditions.
Immediate Medical Attention: Provide information on compound and exposure route to medical professionals.
Suitable Extinguishing Agents: Dry sand, alcohol-resistant foam, CO2, or water spray for surrounding fires.
Specific Hazards: May release toxic vapors including HCl, carbon monoxide, nitrogen oxides, and irritating organic fumes during combustion.
Protective Equipment: Firefighters require self-contained breathing apparatus and chemical-resistant clothing to avoid inhalation and skin contact.
Firefighting Instructions: Cool adjacent containers to prevent pressure buildup. Prevent runoff from entering drains or watercourses.
Personal Precautions: Evacuate unnecessary personnel, ventilate area thoroughly, use respiratory protection for dust/vapor presence. Wear gloves, goggles, and protective clothing.
Environmental Precautions: Prevent product from entering sewers, soil, waterways. Absorb spill in inert material like sand or vermiculite.
Cleanup Methods: Scoop or sweep up bulk material, place in secure, labeled waste containers. Decontaminate surfaces with appropriate solvents (check compatibility). Dispose cleanup materials as hazardous waste.
Safe Handling: Minimize dust or vapor production. Work in fume hood or well-ventilated spaces. Avoid direct contact with eyes, skin, or clothing; never eat, drink, or smoke where chemical handled.
Storage Conditions: Seal containers tightly. Store in dry, cool area protected from sunlight, incompatible substances, moisture, and ignition sources. Provide secondary containment for larger quantities.
Incompatible Materials: Strong oxidants, strong acids, bases, halogens. Avoid storing near combustibles.
Control Parameters: No established occupational exposure limits; follow best practices to reduce airborne concentrations.
Engineering Controls: Use properly functioning fume hoods, local exhaust systems, or enclosures.
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles, full-face shield for splash risk, flame-resistant lab coat, and closed-toe footwear. Use approved respirators if dust, fumes, or inadequate ventilation present.
Hygiene Measures: Wash hands and exposed skin before breaks, at shift end, and after accidental contact. Do not wear contaminated clothing outside work area.
Appearance: Off-white to pale yellow crystalline solid or powder
Odor: Slight chemical or aromatic odor
Odor Threshold: Data not available
pH: Not applicable for solid
Melting Point/Freezing Point: 150-170°C (range varies by purity)
Boiling Point: Decomposes before boiling
Solubility: Poorly soluble in water; soluble in common organic solvents such as DMSO, DMF, ethanol
Vapor Pressure: Negligible at room temperature
Relative Density: 1.2–1.3 g/cm3
Partition Coefficient (log P): >3 (estimated; lipophilic nature)
Evaporation Rate: Not applicable
Vapor Density: Not determined
Flash Point: >180°C (closed cup; estimated)
Flammability: May burn at elevated temperatures, produces hazardous fumes
Auto-ignition Temperature: Not determined
Decomposition Temperature: > 200°C (breakdown releases hazardous gases)
Viscosity: Not applicable for solid
Explosive Properties: Fine dust may form explosive mixtures with air
Chemical Stability: Stable under recommended storage. Sensitive to strong acids, bases, and oxidizing agents.
Reactivity: Avoid contact with strong oxidizers, alkali metals, reducing agents. Product may react with water if impurities present.
Hazardous Decomposition Products: HCl, NOx, small organic volatiles under thermal decomposition or combustion.
Possibility of Hazardous Reactions: No dangerously exothermic reactions in routine handling, but avoid contamination.
Conditions to Avoid: High heat, direct sunlight, open flames, sources of static discharge, moisture.
Routes of Exposure: Inhalation, ingestion, skin or eye contact
Acute Toxicity: Oral LD50 (rat): 300-2000 mg/kg (estimated); may cause acute irritation or systemic effects.
Skin Corrosion/Irritation: Repeated or prolonged contact results in redness and blistering. Sensitization possible.
Eye Damage/Irritation: Severe irritation, lacrimation, potential corneal injury.
Respiratory Sensitization: Dust or vapor could induce allergic symptoms in susceptible individuals.
Chronic Effects: Prolonged exposure may cause liver, kidney, or nervous system complications.
Carcinogenicity/Mutagenicity/Reproductive Toxicity: No data for this compound, but related aromatic/quinoline structures sometimes show mutagenic activity in vitro.
Other Health Hazards: Not enough data for long-term effects. Use caution and minimize unnecessary exposure.
Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments.
Persistence and Degradability: Compound is recalcitrant; slow biodegradation in water and soil anticipated.
Bioaccumulative Potential: Lipophilic nature suggests a risk of accumulation in aquatic organisms.
Mobility in Soil: Low water solubility and high partition coefficient predict adsorption to organic matter and limited groundwater migration.
Other Adverse Effects: Monitor for toxic breakdown products. Avoid release into environment due to unclear persistence.
Disposal Methods: Collect and transfer waste to licensed hazardous waste facility. Incinerate in chemical incinerator equipped with afterburner and scrubber.
Container Disposal: Clean residues from empty packaging before disposal or reuse. Rinse triple times if allowed.
Precautions: Consult national and local guidelines. Never flush to drains, surface water, or soil. Label waste in compliance with regulatory standards.
UN Number: Not assigned for this specific compound
Shipping Name: Not regulated under most transport authorities, unless container quantity and hazard classifies under customs requirements
Transport Hazard Class: See hazard identification; caution for toxic, irritant, and environmental risk
Packing Group: Consult shipment regulations; typically III (minor hazard)
Environmental Hazard: Yes, dangerous for water ecosystems if spilled
Transport Precautions: Package in sturdy, leakproof containers. Avoid exposure to weather, excessive vibration, and temperature extremes during transit.
OSHA Status: Hazardous—refer to chemical hygiene plan requirements
TSCA Inventory: Verify for substance inclusion under Toxic Substances Control Act, U.S.
REACH Status (EU): Not registered—research-use exemption possible for small quantities; comply with lab-use notification if applicable.
SARA Title III Sections 302/304/311/312/313: Not listed as extremely hazardous, but general chemical reporting applies.
California Proposition 65: No listing for parent compound, evaluate analogs for liability.
Other International Regulations: Refer to local, state, and national inventory and restriction programs. Provide safety training and maintain documentation per regional compliance measures.
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