Material Safety Data Sheet: 2,3-DI-O-PARA-TOLUOYL-D-TARTARIC ACID HYDRATE

Identification

Product Name: 2,3-DI-O-PARA-TOLUOYL-D-TARTARIC ACID HYDRATE
Chemical Formula: C20H18O8·xH2O
Chemical Family: Organic acid derivative
SYNONYMS: O,O'-di-p-toluoyl-D-tartaric acid hydrate, TADD-Hydrate
CAS Number: 71616-13-4
Manufacturer Name: Standard chemical supplier
Recommended Use: Chiral resolving agent in pharmaceuticals and chemical laboratories
Contact Info: Listed supplier address, phone, and email

Hazard Identification

GHS Classification: Causes skin and eye irritation, may trigger respiratory irritation, harmful if swallowed
Signal Word: Warning
Hazard Pictograms: Exclamation mark
Hazard Statements: Skin and eye irritant, possible allergic response, harmful if inhaled or ingested
Precautionary Statements: Avoid dust generation, keep container closed, use personal protection, wash thoroughly after handling
Routes of Entry: Inhalation, ingestion, skin contact, eye contact
Potential Health Effects: May cause redness and discomfort; long-term exposure not well documented

Composition / Information on Ingredients

Chemical Name: 2,3-DI-O-PARA-TOLUOYL-D-TARTARIC ACID HYDRATE
Concentration: >95%
Hydrate Component: Water (varies)
Impurities: Trace organic byproducts from synthesis, less than 1%

First Aid Measures

Inhalation: Remove to fresh air, breathe deeply, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water; medical attention if irritation develops
Eye Contact: Rinse eyes for at least 15 minutes under running water; remove contact lenses
Ingestion: Rinse mouth with water, do not induce vomiting, consult physician promptly; ensure airway is clear

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, foam
Unsuitable Extinguishing Media: Direct stream of water for large fires
Fire Hazards: Decomposes to give off acrid smoke and fumes, carbon oxides
Special Equipment: Wear self-contained breathing apparatus and full protective gear
Firefighting Instructions: Move containers from fire area if safe; cool exposed containers with water
Thermal Decomposition Products: Carbon monoxide, carbon dioxide, toluene-derived compounds

Accidental Release Measures

Personal Precautions: Evacuate area, ensure adequate ventilation, avoid breathing dust, wear protective equipment
Environmental Precautions: Prevent spillage from entering waterways or drains, notify authorities
Methods for Cleanup: Sweep or vacuum up, transfer to suitable closed container for disposal, avoid dust formation, clean area with water and detergent

Handling and Storage

Handling: Wear appropriate protective gear, avoid generating dust, handle with care, use under fume hood if possible
Storage: Store in tightly sealed original container, cool and dry location, away from strong oxidizers and acids, protect from light and moisture, label all containers clearly
Storage Temperature: Room temperature, avoid temperature extremes
Incompatible Materials: Strong bases, oxidizing agents, reducing agents

Exposure Controls and Personal Protection

Engineering Controls: Work in well-ventilated area, local exhaust for dust control
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, lab coat, dust mask or NIOSH-approved respirator for dusty environments
Hygiene Measures: Do not eat, drink, or smoke in work area, wash hands after handling, keep contaminated clothing out of living areas

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Faint aromatic
Melting Point: 150-160°C (with decomposition possible)
Boiling Point: Not available
Solubility: Limited in water, soluble in ethanol and methanol
pH: Weakly acidic in solution
Flash Point: Not established for solid
Density: Approximately 1.3 g/cm3
Partition Coefficient (log Kow): Not determined

Stability and Reactivity

Chemical Stability: Stable under normal conditions
Incompatible Materials: Strong oxidizers, bases, acids, moisture
Hazardous Reactions: Reacts with strong bases forming salts, decomposes under heat releasing toxic fumes
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating organic vapors
Conditions to Avoid: Excessive heat, moisture, open flames, direct sunlight

Toxicological Information

Acute Toxicity: Low oral and dermal toxicity based on similar compounds, empirical data lacking
Skin Corrosion/Irritation: May cause mild irritation on repeated or prolonged contact
Eye Damage/Irritation: Causes redness, tearing, or discomfort
Respiratory Sensitization: Prolonged inhalation may cause throat and lung irritation
Carcinogenicity: Not listed by NTP, IARC, OSHA as carcinogenic
Mutagenicity: No data available
Reproductive Effects: No data available on reproductive toxicity
Long-Term Effects: Chronic effects not well studied; proper handling minimizes risk

Ecological Information

Ecotoxicity: Not classified as environmentally hazardous based on available information
Persistence and Degradability: Presumed to degrade slowly under environmental conditions
Bioaccumulation: Bioaccumulation potential not evaluated
Mobility in Soil: Expected to have low mobility in soil due to low water solubility
Other Adverse Effects: Avoid release into water sources and soils to minimize long-term risk

Disposal Considerations

Waste Treatment Methods: Place waste in approved hazardous waste container
Disposal: Dispose through licensed chemical disposal company, follow local/regional/national/international regulations
Contaminated Packaging: Empty containers must be handled as hazardous waste, clean before disposal

Transport Information

UN Number: Not regulated under standard UN hazardous materials guidelines
Transport Hazard Class: Non-hazardous for most transport, special packaging suggested
Packing Group: Not assigned
Environmental Hazards: Not known to present marine pollutant risk
Special Precautions for Transport: Keep container tightly closed, store upright, avoid extreme temperatures or rough handling

Regulatory Information

US Federal Regulations: Not listed as hazardous under TSCA, SARA 302/311/312/313 not triggered
EU Classification: Not classified as dangerous according to Regulation (EC) No 1272/2008
Canada WHMIS: No classification available
Other International Regulations: Not on priority pollutants lists; users should check country-specific regulations
Inventories: Check local chemical inventories for status; typically not restricted