Product Name: 2,3-Di-O-para-toluoyl-D-tartaric acid
Chemical Formula: C20H18O8
Molecular Weight: 386.35 g/mol
Synonyms: (2R,3R)-2,3-Bis(4-methylbenzoyloxy)butanedioic acid
Recommended Use: Intermediate in organic synthesis, chiral resolving agent, analytical reagent
Supplier/Manufacturer: Check local supplier information for up-to-date contacts.
GHS Classification: Not classified as a hazardous substance under current GHS regulations
Label Elements: No pictogram required
Signal Word: Not applicable
Hazard Statements: May cause mild skin or eye irritation in sensitive individuals
Precautionary Statements: Avoid inhalation of dust, avoid contact with eyes and prolonged skin contact, wear protective equipment
Physical Hazards: No significant physical hazard reported under routine conditions
Environmental Hazards: Data not fully available; large spills could impact aquatic environments.
Main Ingredient: 2,3-Di-O-para-toluoyl-D-tartaric acid (CAS Number: 5928-51-2)
Purity: Greater than 98% by HPLC analysis
Impurities: Minor contaminants found below 2%, specific identities typically proprietary to the manufacturer
Additives: None
Inhalation: Move affected person outdoors or to an area with fresh air, provide support as necessary, seek medical attention for persistent symptoms like coughing or breathing difficulty
Skin Contact: Remove contaminated clothing, wash affected area thoroughly with water and soap, seek medical advice if irritation develops
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present and possible, continue rinsing, seek medical attention for persistent discomfort
Ingestion: Rinse mouth out, do not induce vomiting, seek medical advice if a significant quantity is swallowed or if symptoms appear
Suitable Extinguishing Media: Use dry chemical, CO2, water spray, or foam as appropriate for surrounding materials
Unsuitable Extinguishing Media: Direct water jets can spread powder
Specific Hazards: Combustion may yield carbon monoxide, carbon dioxide, irritating fumes or gases
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Procedures: Use water spray to cool fire-exposed containers, avoid inhaling combustion products
Personal Precautions: Ventilate the area, avoid inhalation of dust, wear suitable personal protective equipment including gloves, safety glasses, and dust mask
Environmental Precautions: Prevent entry into waterways, drains, or soil
Cleanup Methods: Collect spillage with care, sweep or shovel into suitable container, avoid raising dust, dispose of according to local regulations
Decontamination: Wash spilled area with water after material pick-up is complete
Handling: Use controls to minimize dust generation, wear protective clothing and equipment, handle in a well-ventilated area, practice good hygiene by washing hands after use
Storage Conditions: Store in tightly closed container, keep in a cool, dry, and well-ventilated place, protect from moisture and direct sunlight
Incompatible Materials: Strong oxidizers, strong bases, materials sensitive to acids
Storage Class: Chemical storage, segregate from incompatible substances
Exposure Limits: No occupational exposure limits established for this substance
Engineering Controls: Use adequate local exhaust ventilation to control dust, consider HEPA filtration for airborne particulates
Respiratory Protection: If dust formation is likely, use approved particulate respirator
Hand Protection: Wear chemical-resistant gloves, nitrile or neoprene recommended
Eye Protection: Use chemical safety goggles or face shield
Skin/Body Protection: Lab coat, closed footwear, cover exposed skin as practical
Hygiene: Wash hands before breaks and after handling, avoid contact with skin, eyes, and clothing
Appearance: White to off-white powder or crystalline solid
Odor: Odorless or faint aromatic scent
pH: 2–3 (1% solution in water)
Melting Point: 188–192°C
Boiling Point: Decomposes before boiling
Flash Point: Not available
Solubility: Slightly soluble in water, soluble in ethanol, methanol, acetone, and other polar solvents
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Data not available
Density: Approx 1.5 g/cm³
Chemical Stability: Stable under recommended conditions of storage and handling
Reactivity: No significant risk under normal use
Hazardous Reactions: No dangerous polymerization reported
Conditions to Avoid: Excessive heat, exposure to moisture, open flames, incompatible chemical agents
Incompatible Materials: Strong acids, strong bases, strong oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, unidentified organic compounds upon burning
Acute Toxicity: No acute toxicity values determined for humans; structurally related compounds show low toxicity in animal testing
Routes of Exposure: Potential absorbance through ingestion, skin, and inhalation
Effects on Skin: May cause mild irritation, no corrosive effects expected
Effects on Eyes: Irritation possible, not expected to cause damage with brief exposure
Effects of Ingestion: May cause stomach upset, nausea, or vomiting; large intake could require medical observation
Sensitization: Not expected based on available data
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA
Mutagenicity: No data available, not considered mutagenic by structural analogy
Long-term Effects: No chronic effects reported for this substance
Ecotoxicity: No detailed testing completed, limited information for aquatic toxicity
Biodegradability: Expected to be biodegradable due to ester and acid functional groups
Bioaccumulation Potential: Low, based on molecular structure
Mobility in Soil: Limited data; generally, organic acids show some mobility in soil, but aromatic ester groups may reduce rate
Water Hazard Classification: Not listed under national inventories
Other Adverse Effects: None known or anticipated from small lab-scale releases
Waste Treatment Methods: Dispose of as chemical waste according to local, regional, or national laws
Container Disposal: Rinse empty containers thoroughly, then send for recycling or incineration where permitted
Unused Product: Collect in clearly labeled, tightly sealed containers for pick-up by licensed waste handler
Precautions: Do not release to environment, avoid flushing to drains or surface water
UN Number: Not regulated
UN Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not classified
Special Precautions for Transport: Store in original container, protect from excess heat, moisture, and breakage
Regulatory Status: Not a hazardous material under international transport rules (ADR, IATA, IMDG)
Inventory Status: Listed in major chemical inventories; confirmed presence in TSCA and REACH depending on supplier
Regulation under OSHA: Not classified as hazardous
SARA Title III sections 302/311/312/313: Substance not subject to reporting
WHMIS (Canada): Not controlled
GHS Labeling: No pictogram or hazard statement required
Restriction Status: No restrictions identified under EU, U.S., or international chemical regulations for use, handling, or disposal
Other Requirements: Users should confirm current requirements with local authorities and maintain all safety documentation on file
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