Material Safety Data Sheet for 2-(2'-Hydroxy-3',5'-di-tert-butylphenyl)-5-chlorobenzotriazole

Identification

Chemical Name: 2-(2'-Hydroxy-3',5'-di-tert-butylphenyl)-5-chlorobenzotriazole
Common Name: UV-327
CAS Number: 3864-99-1
Formula: C20H24ClN3O
Recommended Uses: Light stabilizer for plastics, coatings, adhesives, and fibers
Supplier: Manufacturer or distributor details on shipping documentation
Emergency Phone: Refer to local regulatory listings for poison control and chemical emergency hotlines

Hazard Identification

GHS Classification: Skin irritant (Category 2), Eye irritant (Category 2A), Specific target organ toxicity (Category 3)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark
Routes of Entry: Inhalation, skin contact, ingestion, eye contact
Potential Health Effects: Repeated skin exposure causes dryness or cracking, inhalation of dust irritates respiratory tract, ingestion may upset stomach
Precautionary Statements: Avoid breathing dust, wash hands after handling, wear protective gear
Unknown Toxicity: Not all hazards under routine use are documented

Composition / Information on Ingredients

Chemical: 2-(2'-Hydroxy-3',5'-di-tert-butylphenyl)-5-chlorobenzotriazole
Synonyms: UV Absorber 327; Tinuvin 327
Concentration: >99%
Impurities or Stabilizing Additives: Negligible, no significant impurities known to contribute risk in expected use

First Aid Measures

Inhalation: Move person to fresh air, keep comfortable for breathing, provide oxygen if breathing becomes difficult, consult medical attention for persistent symptoms
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing and shoes, seek medical help if irritation develops
Eye Contact: Rinse eyes gently with water for several minutes, remove contact lenses if present and easy to do, continue rinsing until irritation subsides, consult a physician
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice if feeling unwell, never give anything by mouth to an unconscious person
Most Important Symptoms: Skin irritation, redness, eye discomfort, respiratory irritation

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, water spray, alcohol-resistant foam, carbon dioxide
Unsuitable Extinguishing Media: Strong water jets may spread spilled product
Special Hazards: Burning releases toxic fumes, including oxides of carbon, nitrogen, and hydrogen chloride
Advice for Firefighters: Use self-contained breathing apparatus and full protective gear, keep run-off away from water bodies and drains
Fire Fighting Procedures: Avoid inhaling combustion gases, isolate area if safe to do so, cool containers exposed to fire with water

Accidental Release Measures

Personal Precautions: Wear comprehensive protective equipment including gloves, goggles, and dust mask, remove unprotected persons from area
Environmental Precautions: Prevent further leakage or spillage, restrict entry into waterways, drains, and soil
Containment Methods: Sweep up and collect in appropriate containers for disposal, avoid generating airborne dust
Cleanup Methods: Use non-sparking tools and equipment; ventilate area, wash spill site with soap and water after removal

Handling and Storage

Handling: Minimize dust generation, avoid inhalation and direct contact with skin or eyes, use in well-ventilated locations, wash hands thoroughly after use
Technical Measures: Earth all equipment, use explosion-proof equipment where dust or static discharge risk is present
Safe Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated area, isolate from incompatible substances (strong acids, oxidizers)
Storage Incompatibilities: Separate from foodstuffs, beverages, and animal feed, keep away from flames and high-temperature sources

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific limits set for this substance; control dust and aerosol as nuisance particulates
Engineering Controls: Local exhaust ventilation, process enclosures, avoid dust accumulation
Personal Protective Equipment:

  • Respiratory: Approved dust mask or particulate respirator in areas of poor ventilation or dust generation
  • Skin: Chemical-resistant gloves, laboratory coat or overalls
  • Eye: Safety goggles with side shields
  • Other: Provide eyewash stations, emergency showers near work area
Hygiene Measures: Do not eat, drink, or smoke in handling area, wash hands before and after each use, change contaminated clothing

Physical and Chemical Properties

Appearance: Off-white or pale yellow crystalline powder
Odor: Odorless or faint organic aroma
Melting Point: 150–158°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: >180°C
Evaporation Rate: Not available
Flammability: Not highly flammable, but combustible
Vapor Pressure: <0.00001 mmHg at 25°C
Solubility: Practically insoluble in water; soluble in organic solvents (e.g., acetone, toluene)
Partition Coefficient (log Kow): >5
Density: 1.2 – 1.3 g/cm³
pH: Not applicable (solid)
Decomposition Temperature: >220°C

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Reactive Hazards: Reacts with strong acids, strong oxidizing agents
Hazardous Decomposition Products: Emits toxic fumes including nitrogen oxides, hydrogen chloride, and carbon oxides during combustion or decomposition
Polymerization: Not expected to occur
Conditions to Avoid: High temperatures, ignition sources, exposure to strong oxidizers or acids

Toxicological Information

Possible Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity (oral, rat): LD50 greater than 15000 mg/kg (estimated from similar compounds)
Acute Toxicity (dermal): No data available, expected to have low toxicity
Skin Irritation: Causes mild to moderate irritation, possible drying with repeated or prolonged exposure
Eye Irritation: Causes significant discomfort and redness
Respiratory Effects: Dust inhalation produces irritation, coughing
Carcinogenicity: No components classified as carcinogens by IARC, OSHA, or NTP
Mutagenicity: Tests with similar benzotriazoles show no clear evidence for mutagenic action
Reproductive Effects: No conclusive animal studies for reproductive toxicity
Chronic Effects: Prolonged or repeated exposure aggravates dermatitis or respiratory conditions in sensitive individuals

Ecological Information

Ecotoxicity (Aquatic): Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable, demonstrates persistence in soil and sediment
Bioaccumulation Potential: High potential due to octanol-water partition coefficient (log Kow >5)
Mobility in Soil: Strong adsorption to sediment and organic matter, low mobility in groundwater
Other Adverse Effects: Potential hazard for chronic aquatic toxicity, avoid release to natural waters

Disposal Considerations

Disposal Methods: Dispose of in accordance with local, national, and international regulations for chemical waste
Contaminated Packaging: Triple rinse container, offer for recycling if available, otherwise manage as hazardous waste
Special Instructions: Do not dispose of into surface waters, storm drains, or landfills without pre-treatment, incineration recommended for substantial quantities

Transport Information

UN Number: Not regulated as a dangerous good for transport by ADR/RID/IMDG/IATA
Proper Shipping Name: As registered, usually shipped as non-hazardous chemical
Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant, but minimize exposure to environment
Transport Precautions: Avoid temperature extremes, treat as a chemical shipment, keep away from incompatible chemical cargo

Regulatory Information

US TSCA: Listed on Toxic Substances Control Act inventory
EU REACH: Registered; specific restrictions for commercial and consumer use may apply
Canada DSL/NDSL: Listed
China IECSC: Listed
Japan ENCS: Listed
GHS Labeling: Follows UN GHS classification criteria; local requirements may differ
Workplace Control: Occupational exposure regulations and training requirements enforced by OSHA, EU-OSHA, or similar national agencies