Product Name: (1S,2S)-(+)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Synonyms: 4-Nitrophenyl serinol, p-Nitrophenyl-serinol
CAS Number: 36652-92-7
Recommended Use: Laboratory research, intermediate for synthesis
Supplier: Chemical provider, reach out to the laboratory manager for procurement records
Emergency Contact: Institutional safety office or poison control center
Address: Refer to institutional or provider location
Phone Number: Listed on the laboratory’s emergency protocol sheet
Classification: Acute toxicity (oral), Skin irritation, Eye irritation, Environmental hazard (aquatic)
GHS Pictograms: Exclamation mark, Health hazard, Environmental hazard
Hazard Statements: Harmful if swallowed, Causes skin irritation, Causes serious eye irritation, Toxic to aquatic life
Precautionary Statements: Wash hands thoroughly after handling, Avoid release to environment, Wear protective gloves/eye protection/face protection, If on skin: Wash with plenty of water, If in eyes: Rinse cautiously with water for several minutes
Signal Word: Warning
Specific Hazards: Allergic skin reactions, delayed effects from overexposure, environmental bioaccumulation
Chemical Name: (1S,2S)-(+)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
CAS Number: 36652-92-7
Percentage: 99% or higher (research grade, purity may vary by supplier)
Impurities: Trace organic byproducts from synthesis, not expected to contribute significant risk under normal lab handling
Inhalation: Remove to fresh air, seek medical attention for persistent discomfort, support breathing if necessary
Skin Contact: Remove contaminated clothing, rinse affected area with soap and water, monitor for rash or irritation
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, hold eyelids open, consult physician
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical attention
General Advice: Always call poison control for guidance during significant exposures, bring SDS to the physician
Most Important Symptoms: Irritation of mucous membranes, skin rash, burning eyes, vomiting if ingested
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: Do not use direct water jets on chemical fires involving organics
Special Hazards Arising: Hazardous decomposition products may include nitrogen oxides, carbon oxides
Protective Equipment: Firefighters use self-contained breathing apparatus, full protective gear
Advice for Firefighters: Evacuate area, contain runoff, avoid inhaling combustion fumes, ventilate enclosed spaces post-event
Personal Precautions: Use appropriate personal protective equipment including gloves, lab coat, safety goggles, and mask
Emergency Procedures: Evacuate unnecessary personnel, provide adequate ventilation, restrict access
Methods for Containment and Cleaning Up: Avoid dust generation, collect dry powder with disposable absorbent, wipe residue with damp cloth and detergent, dispose as hazardous waste
Environmental Precautions: Prevent further leakage or spillage, do not let product enter drains or watercourses
Handling: Use in a designated chemical fume hood or well-ventilated area, minimize aerosol and dust formation, avoid contact with skin, eyes, and clothing, handle with care to prevent breakage or spills
Storage: Store in tightly closed original container, in a cool and dry area, segregated from incompatible chemicals such as strong oxidizers, acids, bases, protected from light and excess heat, label containers clearly
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Engineering Controls: Local exhaust ventilation, chemical fume hood, safety shower, eyewash stations
Personal Protective Equipment: Nitrile gloves, chemical splash goggles, lab coat, closed-toe shoes, face shield for large volumes
Respiratory Protection: Use approved respirator if dust is generated or aerosol risk exists
Environmental Exposure Controls: Prevent release into the environment, use waste containers for contaminated disposables
Hygiene Measures: Wash hands after handling, avoid eating, drinking, or smoking in lab, clean work surfaces after use
Appearance: Pale yellow solid, crystalline powder
Odor: Slight chemical odor, not pronounced
Odor Threshold: Not determined
pH: Unknown in solid state, becomes acidic in solution
Melting Point / Freezing Point: 153-155°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not determined
Evaporation Rate: Negligible
Flammability: Not flammable under normal conditions
Vapor Pressure: Not relevant
Solubility: Slightly soluble in water, soluble in ethanol and methanol
Partition Coefficient: Not determined
Decomposition Temperature: Above 160°C
Viscosity: Not relevant for solid form
Chemical Stability: Stable under storage at recommended conditions, sensitive to heat and light over longer periods
Possible Hazardous Reactions: Reacts with strong oxidizers, acids, bases releasing toxic gases
Conditions to Avoid: Excessive heat, sources of ignition, direct sunlight, humidity
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, hazardous organic fragments
Incompatible Materials: Acids, bases, oxidizers; contamination from foreign materials
Acute Toxicity: Harmful if swallowed, toxic in large doses, oral LD50 (rat) not established, based on chemical analogs may be in range 200-2000 mg/kg
Skin Corrosion / Irritation: Causes irritation on contact, possible allergic reaction with repeated exposure
Serious Eye Damage: Causes irritation, redness, possible corneal injury with sufficient exposure
Respiratory Sensitization: Irritating to respiratory tract if inhaled as dust
Germ Cell Mutagenicity: Not tested, related nitro compounds possess mutagenic potential
Carcinogenicity: Not classified as carcinogenic by IARC, ACGIH, NTP, or OSHA
Reproductive Toxicity: No evidence available, handle with care as nitro compounds in general carry increased risk
Target Organ Effects: Eyes, skin, mucous membranes, possibly liver and kidneys with chronic exposure
Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments
Persistence and Degradability: Nitroaromatic compounds resist rapid biodegradation, likely persistent
Bioaccumulative Potential: Potential for bioaccumulation not fully known, chemical structure suggests some risk
Mobility in Soil: Likely moderate, still largely contained in soils but can travel in water
Other Adverse Effects: Potential for negative impact on algae, daphnia, fish, limited natural breakdown
Waste Treatment Methods: Collect material in sealed, clearly labeled hazardous waste containers
Disposal of Product: Send waste to approved hazardous chemical disposal facility, avoid landfill or incineration without proper permits
Disposal of Contaminated Packaging: Rinse thoroughly, deface labels, dispose as hazardous chemical waste
Precautions for Disposal: Avoid contamination of groundwater, follow all local, regional, and national regulations
Environmental Precautions: Do not let spill or rinse water flow into surface water or sewage systems
UN Number: Not assigned for this specific compound, ship as regulated organic solid according to local rules
Proper Shipping Name: Toxic organic solid, n.o.s. (contains nitroaromatic compound)
Transport Hazard Class: 6.1 (toxic substances, as per ADR/IMDG)
Packing Group: III (for moderate hazard materials)
Environmental Hazards: Marine pollutant under IMDG
Special Precautions for Transport: Avoid mechanical shock, keep container tightly closed, handle only by trained personnel, note DOT and IATA regulations for laboratory chemicals
OSHA Status: Not specifically listed, general duty to protect applies
TSCA Inventory: Compound may not be explicitly listed, check latest regulatory updates
SARA Title III: Not subject to SARA Tier II reporting as individual chemical, monitor cumulative nitroaromatic usage
California Proposition 65: Not listed, use caution due to chemical class
EPA Regulations: Subject to hazardous waste management if disposed
State Regulations: Compliance required with state-specific chemical handling guidance
WHMIS (Canada): Controlled product, clear training for lab staff required
EU Regulations: Classified as hazardous, appropriate pictograms and warnings mandatory on label
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