Product Name: (1S,2S)-(-)-1,2-diaminocyclohexane D-tartrate
Chemical Formula: C8H20N2O6
Other Names: Diaminocyclohexane tartrate, Diaminocyclohexane D-tartrate salt
CAS Number: 64739-58-6
Recommended Use: Chiral resolving agent, pharmaceutical intermediate, ligand in asymmetric catalysis
Supplier Details: Manufacturer address, emergency contact phone number, and information line
Synonyms: (S,S)-1,2-Diaminocyclohexane D-tartrate, DACH D-tartrate
Relevant Uses: Laboratory reagent, chiral auxiliary in synthesis
GHS Classification: Eye irritation (Category 2), Skin irritation (Category 3), Specific target organ toxicity - single exposure (Category 3)
Label Elements: Pictograms for irritant and health hazard
Signal Word: Warning
Hazard Statements: Causes mild skin irritation. May cause eye irritation. Ingestion may cause discomfort or nausea. Dust may irritate respiratory tract.
Precautionary Statements: Do not breathe dust, wash hands thoroughly, avoid contact with eyes, wear protective gloves and eyewear
Main Health Hazards: Respiratory irritation, skin and eye irritation on direct contact, non-carcinogenic by existing studies
Chronic Effects: None expected under normal exposure, but repeated contact may increase sensitivity
Environment Hazards: Avoid release to environment, as aquatic toxicity data remain limited
Chemical Name: (1S,2S)-(-)-1,2-diaminocyclohexane D-tartrate
CAS Number: 64739-58-6
Percentage by Weight: 95-100%
Impurities: Unreacted tartrate, traces of starting materials (less than 1%)
Stabilizers or Additives: None identified in typical commercial samples
Hazardous Components: No additional hazardous components in standard preparation
Typical Appearance: White to off-white crystalline powder
General Advice: Seek medical advice for any persistent symptoms or exposures
Inhalation: Move affected person to fresh air, allow rest in comfortable position, provide oxygen if breathing is difficult, get medical attention if symptoms persist
Skin Contact: Wash affected area thoroughly with soap and water, remove contaminated clothing, launder clothing before reuse, consult a doctor for persistent irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical attention if irritation develops or persists
Ingestion: Rinse mouth with water, do not induce vomiting, give water to drink if person is conscious, seek medical advice, present label or container if possible
Most Important Symptoms: Sore throat, coughing, minor skin or eye redness, headaches if exposed to large amounts
Notes to Physician: Treat symptomatically, monitor for allergic reactions or complications
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide extinguisher
Unsuitable Media: Direct water jet in confined space may increase contamination risk
Fire Hazards: Material is not regarded as highly flammable, but thermal decomposition may generate irritating fumes like nitrogen oxides or carbon oxides
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus, protective clothing resistant to chemical exposure
Firefighting Instructions: Remove containers from fire area if safe to do, apply water spray to exposed containers to keep them cool
Combustion Products: Oxides of carbon, oxides of nitrogen, organic fragments
Additional Risks: Dust formation in air can present a minor explosion risk under rare circumstances
Personal Precautions: Use appropriate respiratory protection if dust forms, avoid contact with skin and eyes, ensure adequate ventilation in spill area, restrict access to spill area
Protective Equipment: Wear chemical splash goggles, gloves (nitrile or latex), laboratory coat
Environmental Precautions: Prevent further leakage or spillage, avoid release into soil, drains, or waterways
Methods for Clean-Up: Sweep up with non-sparking tools, collect spilled material into clearly labeled containers for disposal, clean area with damp cloth or absorbent material
Other Precautions: Dispose of contaminated cleaning materials as hazardous waste
Decontamination: Use water and detergent solution for ground surfaces
Reporting: Report large spills or exposures to local authorities according to regulations
Safe Handling: Minimize dust generation and accumulation, wash hands thoroughly after handling, avoid contact with eyes, skin, and clothing
Storage Conditions: Store in original sealed container at room temperature, keep away from sources of ignition, acids, and incompatible materials
Incompatible Materials: Strong oxidizers, strong acids, bases, or reducing agents
Packaging Materials: Polyethylene or glass containers recommended, avoid storing with food or animal feed
Handling Instructions: Use only in well-ventilated areas, avoid eating, drinking, or smoking when using this chemical
Special Storage Requirements: Keep container tightly closed when not in use, no special ventilation requirements for usual laboratory settings
Further Information: Maintain inventory control to avoid overstocking or unnecessary storage
Exposure Limits: No specific occupational exposure limits set by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation at sources of dust generation, laboratory fume hood preferred for handling solids
Personal Protection: Chemical-resistant gloves, splash goggles, lab coat, in high dust environments use N95 respirator or equivalent
Eye and Face Protection: Tight-fitting chemical safety goggles
Skin Protection: Gloves resistant to chemical penetration, full coverage clothing
Respiratory Protection: Respirator wear when dust levels are high or in poorly ventilated settings
General Hygiene Measures: Avoid inhalation, wash hands after handling, avoid eating or drinking while handling
Environmental Controls: Use containment when pouring or moving powder to prevent dust transfer
Appearance: White to pale crystalline powder
Odor: Faint, not distinctive
Odor Threshold: Not determined
pH: Approximately 6.5 (1% aqueous solution)
Melting Point / Freezing Point: 194-201 °C (decomposes)
Boiling Point: Not applicable (decomposes on heating)
Flash Point: Not flammable under standard test conditions
Evaporation Rate: Not volatile
Flammability (Solid): Not readily combustible
Upper/Lower Flammability: Not applicable
Vapor Pressure: Negligible
Density: 1.45 g/cm³ (approximately)
Solubility in Water: Slightly soluble, forms suspension in water
Partition Coefficient (n-octanol/water): Not established
Auto-ignition Temperature: Not applicable
Decomposition Temperature: Above 180 °C
Viscosity: Not applicable
Molecular Weight: 244.25 g/mol
Chemical Stability: Stable at recommended storage conditions, sensitive to strong oxidants
Conditions to Avoid: Excess moisture, open flames, sources of ignition, prolonged exposure to air
Materials to Avoid: Strong oxidizing agents, strong acids or bases, reducing agents
Hazardous Decomposition Products: May produce nitrogen oxides, carbon monoxide and dioxide, secondary amines on heating
Polymerization: Will not occur under normal handling conditions
Reactivity: Low under ordinary use, risk increases with exposure to strong acids or bases
Storage Life: Up to two years if stored properly, check regularly for changes in color or clumping
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Oral rat LD50 > 2000 mg/kg, low hazard by acute exposure
Inhalation: Dust inhalation may cause mild respiratory irritation, especially in sensitive individuals
Skin Contact: May cause irritation, prolonged and repeated skin contact increases risk
Eye Contact: Redness, pain or discomfort possible
Ingestion: Low oral toxicity, large doses may lead to gastrointestinal upset
Chronic Effects: No evidence of sensitization or allergenicity from available data
Carcinogenicity: Not classified as carcinogenic by ACGIH, IARC, NTP, or OSHA
Mutagenicity: No data supporting mutagenic risk
Reproductive Toxicity: No reported adverse reproductive effects
Other Information: No known target organ toxicity in animal studies
Ecotoxicity: Limited data, may be slightly harmful to aquatic organisms, avoid release to environment
Persistence and Degradability: Expected to degrade slowly in soil and water
Bioaccumulation Potential: Low, unlikely to persist in biological tissues
Mobility in Soil: Moderately mobile, may travel in groundwater temporarily
Other Adverse Effects: None known with normal use patterns
Aquatic Toxicity: Low concern, but should take steps to prevent unnecessary release
Disposal Impacts: Avoid contamination of surface waters and municipal systems
Waste Handling: Collect solid waste in clearly labeled containers, avoid creating dust
Disposal Methods: Dispose of as chemical waste in compliance with local, state, and national regulations
RCRA Status: Not listed as hazardous under US federal waste regulations
Container Disposal: Triple rinse empty containers before disposal or recycling, ensure all residues cleared
Incineration: Permitted at approved facilities
Other Disposal Considerations: Do not release to surface water, stormwater, or unapproved landfills
UN Number: Not regulated as dangerous goods
Proper Shipping Name: Not classified as hazardous for transport
Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Transport Labels: None required
Special Precautions for User: Ensure containers are tightly sealed, minimize exposure during loading and unloading
Additional Transport Requirements: Keep product dry and protected from rough handling
TSCA Inventory: Listed or complies with inventory requirements
REACH (EU): Not specifically registered, used in research and development quantities
OSHA: Not classified as hazardous chemical under the OSHA Hazard Communication Standard
SARA Title III: Not subject to specific reporting requirements
California Proposition 65: Not listed as requiring warning
Canadian Regulations: Meets WHMIS criteria for lab use, not controlled product
Other International Regulations: No separate restrictions identified
Labeling Requirements: Handle according to chemical laboratory best practices and standard PPE requirements
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