Product Name: (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Chemical Formula: C9H12N2O4
Synonyms: 2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Recommended Use: Pharmaceuticals, chemical research, synthesis intermediate
Manufacturer: Specific chemical suppliers or research labs
Contact Information: Refer to supplier for address and emergency contact
Emergency Telephone Number: Poison control, local emergency services
CAS Number: 78191-66-7
GHS Classification: Acute Toxicity (Oral, Category 4), Skin Irritation (Category 3), Eye Damage (Category 2A), Specific Organ Toxicity (Single Exposure, Category 3)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves and eye protection
Potential Health Effects: Ingestion may result in nausea and abdominal pain. Direct contact with skin or eyes may lead to irritation, redness, or stinging. Inhalation may cause coughing or shortness of breath.
Environmental Hazards: Toxic to aquatic life, risk of long-term adverse effects.
Chemical Identity: (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity: Typically above 98%
Impurities: Trace amounts of related compounds, residual solvents below 0.5%
Additives: None indicated
Molecular Weight: 212.21 g/mol
Inhalation: Move to fresh air, keep at rest. Obtain medical attention if symptoms persist. Remove contaminated clothing and loosen tight clothing.
Skin Contact: Wash skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Seek medical attention for any ongoing pain or irritation.
Ingestion: Rinse mouth thoroughly with water. Do not induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person.
Suitable Extinguishing Media: Dry chemical, CO2, water spray, or alcohol-resistant foam
Unsuitable Extinguishing Media: High-volume water jets.
Hazardous Combustion Products: Nitrogen oxides, carbon oxides, other unidentified toxic fumes
Protective Equipment: Wear self-contained breathing apparatus and full protective gear.
Fire Hazards: Avoid inhaling combustion gases; chemical may decompose to hazardous byproducts under fire conditions.
Special Procedures: Prevent run-off from entering drains or watercourses.
Personal Precautions: Keep unprotected individuals away, use approved respiratory protection, wear suitable gloves and eye protection.
Environmental Precautions: Avoid contamination of soil, drains, and surface or groundwater systems. Collect large spills to prevent environmental release.
Methods for Cleaning Up: Collect spillage with inert absorbent material (such as sand), transfer to container for disposal. Ventilate contaminated area. Clean surfaces with soap and water.
Handling: Handle in well-ventilated area. Avoid generating airborne dust. Prevent contact with eyes, skin, and clothing. Wash thoroughly after use.
Storage Conditions: Store in original container, tightly closed, at room temperature (15–25°C). Keep away from direct sunlight, oxidizers, incompatible materials.
Incompatible Materials: Strong oxidizers, acids, bases. Do not store near food or beverages.
Specific Handling Precautions: Use proper laboratory techniques; prevent static discharge.
Exposure Limits: Not established for this compound; follow workplace hygiene standards for hazardous chemicals.
Engineering Controls: Laboratory fume hood, local exhaust ventilation.
Personal Protective Equipment: Splash-proof goggles, chemical-resistant gloves (nitrile recommended), lab coat, respiratory protection if dust generated.
Hygiene Measures: Do not eat, drink, or smoke while working. Wash hands before breaks and after handling material. Remove contaminated clothing immediately.
Appearance: Off-white to pale yellow crystalline powder
Odor: Odorless or slight chemical scent
Melting Point: 155–158 °C
Boiling Point: Not determined
Solubility: Soluble in water, methanol, ethanol; low solubility in non-polar solvents
pH: 6.0 - 7.5 (1% solution in water)
Flash Point: Not data available
Vapor Pressure: Negligible at room temperature
Density: ~1.45 g/cm³
Partition Coefficient (Log Kow): Not determined
Chemical Stability: Stable under recommended storage conditions.
Reactivity: May react violently with strong oxidizing agents.
Possibility of Hazardous Reactions: Not anticipated under normal use.
Conditions to Avoid: Excessive heat, incompatible materials, high humidity.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, other toxic gases on combustion or decomposition.
Likely Routes of Exposure: Inhalation, skin, eye, ingestion.
Acute Effects: May cause irritation of respiratory tract, eyes, and skin. Harmful if swallowed.
Chronic Effects: Prolonged or repeated exposure may cause organ damage, particularly to kidneys or liver.
LD50 (Oral, Rat): Estimated 300-2,000 mg/kg
Dermal Toxicity: Data unavailable; consider as harmful
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Reproductive Toxicity: Not established
Symptoms of Exposure: Nausea, dizziness, irritation, headache, coughing.
Ecotoxicity: Harmful to aquatic organisms. May cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Likely to degrade slowly under environmental conditions.
Bioaccumulative Potential: Not established, likely low
Mobility in Soil: Moderate mobility due to water solubility
Other Adverse Effects: Release into waterways should be avoided, do not allow undiluted product or large quantities to reach water systems.
Waste Disposal Methods: Dispose of contents and containers through a licensed waste disposal contractor. Incineration in an approved facility preferred for large quantities.
Contaminated Packaging: Dispose of according to local regulations. Containers must be triple rinsed or thoroughly cleaned before recycling or reuse.
Additional Considerations: Avoid disposal into the environment. Follow all applicable local, regional, and national regulations.
UN Number: Not classified as hazardous for transport according to current regulations.
UN Proper Shipping Name: No data available
Transport Hazard Class: Not regulated
Packing Group: No data available
Environmental Hazards: Not applicable under current shipping guidelines; avoid discharge in transport.
Special Transport Precautions: Protect containers from damage, use secondary containment for bulk shipments.
Regulatory Status: Follow local transport regulations for laboratory chemicals.
TSCA Status: Not listed on US TSCA inventory; for research and development only
EPA Regulations: Not specifically regulated
FDA Status: Not approved for human or veterinary drug use
WHMIS Classification: D2B (Toxic material causing other toxic effects)
OSHA: Treat as hazardous chemical
SARA Title III: Not listed as an extremely hazardous substance
EU Classification: Not classified under CLP for supply and use
Additional Information: Consult national, state, and local regulations for specific handling and labeling requirements.
Providing high-quality chemical products and logistics solutions for global trade partners.
