Product Name: 1-Propanol, 3-chloro-
Synonyms: 3-Chloropropan-1-ol
Error Threshold Level: Consult laboratory guidelines for permissible exposure limits
Chemical Formula: C3H7ClO
Molecular Weight: 94.54 g/mol
Manufacturer: Refer to supplier or manufacturer address provided on shipment documentation
Contact Information: Emergency phone and customer support available through MSDS supplier
Uses: Laboratory reagent, synthesis intermediate, specialty chemical in organic reactions
Classification: Flammable liquid, Acute toxicity (oral, dermal, inhalation), Skin and eye irritant
Signal Word: Danger
Hazard Statements: Causes severe eye and skin irritation, poses risk of respiratory tract irritation, may cause central nervous system depression, can be harmful or fatal if swallowed or inhaled
Pictograms: Flammable, Acute Toxicity, Irritant, Health hazard
Known Acute Symptoms: Coughing, headaches, red or blistered skin, irritation of mucous membranes, dizziness
Chronic Effects: Possible liver or kidney damage with prolonged exposure
Routes of Entry: Inhalation, skin absorption, oral ingestion
Chemical Name: 1-Propanol, 3-chloro-
CAS Number: 627-30-5
Concentration: Greater than 99% purity
Impurities: Trace other propanol derivatives or water less than 0.5%
Dangerous Components: 1-Propanol, 3-chloro-
Inhalation: Move affected individual into fresh air as soon as possible, monitor breathing, provide artificial respiration or oxygen as needed, call emergency services for persistent symptoms
Skin Contact: Remove contaminated clothing and wash skin with soap and plenty of water for a minimum of 15 minutes, seek medical advice if irritation persists
Eye Contact: Flush eyes with running water for at least 15 minutes holding eyelids open, avoid rubbing the eyes, immediate medical attention is recommended
Ingestion: Do not induce vomiting, rinse mouth with water, offer water to drink if the person is alert, get immediate medical assistance
Most Important Symptoms: Redness, severe irritation, loss of consciousness in severe cases, nausea
Notes to Physician: Treat symptomatically, consider gastric lavage for significant ingestion, monitor for respiratory depression
Suitable Extinguishing Media: Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray
Unsuitable Extinguishing Media: Strong water jet may spread flammable liquid
Specific Hazards: Vapors can form explosive mixtures with air, toxic or corrosive gases like hydrogen chloride and phosgene possible on thermal decomposition
Protective Equipment for Firefighters: Full protective clothing and self-contained breathing apparatus
Special Fire Procedures: Use water spray to cool unopened containers, prevent runoff from contaminating soil or waterways
Combustion Products: Carbon monoxide, carbon dioxide, hydrogen chloride, possibly other toxic gases
Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid breathing vapors, prevent contact with skin or eyes
Protective Equipment: Chemical-resistant gloves, splash goggles or face shield, lab coat or coveralls, suitable respiratory protection if airborne levels exceed limits
Environmental Precautions: Prevent chemical from entering waterways, drains, or sewers, inform environmental protection authorities as required by local laws
Clean-up Methods: Absorb spill using inert, non-combustible material like sand, collect residue in a suitable container for disposal, wash the spill site thoroughly with water and detergent
Decontamination: Ensure all contaminated materials and equipment are decontaminated before re-use
Handling: Keep container tightly closed, use in well-ventilated areas, avoid inhalation of vapors or mists, prevent skin and eye contact, ground and bond containers for transfer, use spark-proof equipment
Storage: Store in cool, dry, well-ventilated place away from sources of ignition and incompatibles like strong oxidizing agents and acids, keep container tightly sealed and upright, segregate from food and drink
Storage Temperature: Recommended storage under 25°C, avoid freezing
Packaging Materials: Use containers made from compatible materials such as glass, high-density polyethylene, or steel lined with corrosion-resistant material
Incompatibles: Strong oxidizing agents, strong acids, alkali metals
Occupational Exposure Limits: Consult national and local regulations for threshold limit values; typical TWA (8hr) may be in the low ppm range
Engineering Controls: Use local exhaust ventilation to minimize vapor concentrations, ensure eyewash stations and emergency showers are accessible
Personal Protective Equipment (PPE): Use chemical-resistant gloves (nitrile, butyl rubber), splash goggles, lab coat, and closed-toe shoes, use respiratory protection with organic vapor cartridges if ventilation inadequate
Hygiene Measures: Do not eat, drink, or smoke in work area, wash hands thoroughly after handling, promptly remove contaminated clothing
Environmental Exposure Controls: Limit release to the environment, treat contaminated air before venting outdoors
Appearance: Colorless to pale yellow liquid
Odor: Sharp, alcohol-like
Melting Point: -80°C
Boiling Point: 156-160°C
Flash Point: Approx. 56°C (closed cup)
Evaporation Rate: Moderate, similar to alcohols
Flammability: Highly flammable liquid and vapor
Explosion Limits: Lower: ~1.8% Vol; Upper: ~13% Vol
Vapor Pressure: 2.3 mmHg at 20°C
Vapor Density: Approximately 3.3 (air = 1)
Solubility: Miscible with water, alcohols, ethers; limited solubility in hydrocarbons
Partition Coefficient (log Kow): Approximately 0.3
Auto-ignition Temperature: 415°C
Decomposition Temperature: Data not available
pH: Neutral to slightly acidic in aqueous solution
Viscosity: Low, flows readily at room temperature
Chemical Stability: Stable under recommended handling and storage conditions
Hazardous Reactions: May react vigorously with strong oxidizers and acids, may release toxic gases under combustion
Conditions to Avoid: Heat, sparks, open flames, direct sunlight, electrostatic discharge
Materials to Avoid: Strong acids, bases, oxidizers, alkali metals, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen chloride, phosgene under fire conditions
Polymerization: Does not polymerize under normal conditions
Acute Toxicity: LD50 (oral, rat): 180 mg/kg; LD50 (dermal, rabbit): estimated 350 mg/kg
Irritation: Severe skin and eye irritation reported in animal studies
Sensitization: No data on skin sensitization, but potential exists due to reactivity
Inhalation: High vapor concentrations cause dizziness, respiratory tract irritation, CNS depression
Chronic Exposure: Repeated exposure may cause liver, kidney, or nervous system effects, based on related chloropropanols
Mutagenicity/Carcinogenicity: No specific data available, caution advised due to similarities with toxic chlorinated compounds
Routes of Exposure: Eye, skin, inhalation, ingestion all pose risk of toxicity or injury
Target Organs: Liver, kidneys, central nervous system, mucous membranes
Ecotoxicity: Harmful to aquatic life with long-lasting effects, LC50 (fish, 96 hr): 15 mg/L
Persistence and Degradability: Expected to degrade under aerobic conditions, but breakdown intermediates may persist
Bioaccumulative Potential: Low based on log Kow, but accumulation possible in aquatic organisms
Mobility in Soil: High mobility in soil and water due to miscibility, risk of groundwater contamination
Other Adverse Effects: May contribute to chemical oxygen demand in effluent streams, possible byproduct formation under sunlight exposure
Waste Treatment Methods: Collect waste in sealed, chemically compatible containers, label contents with proper identification and hazard warnings
Disposal Product: Treat as hazardous chemical waste; incineration under controlled, high-temperature conditions recommended
Contaminated Packaging: Dispose of ash and packaging as hazardous waste in compliance with local, regional, or national regulations
Do Not Release: Avoid pouring into drains, waterways, or unsecured landfill
Regulatory Restraints: Must follow hazardous waste transport and treatment laws, including RCRA or similar regional statutes
UN Number: 2689
UN Proper Shipping Name: 3-Chloro-1-propanol
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Label Requirements: Flammable liquid, environment hazardous
Marine Pollutant: Yes (potential groundwater contaminant and aquatic toxin)
Environmental Hazards: Mark packaging and documentation according to local/national rules
Special Precautions: Segregate from incompatible substances during storage and transport, secure containers to prevent leakage in transit
U.S. Regulations: Subject to OSHA hazardous chemical labeling and storage standards, SARA 313 reporting may be required for workplace quantities
EU Directives: Classified Dangerous Substance, subject to REACH registration and workplace hazard communication requirements
Canada: WHMIS Classification - Flammable and toxic; workplace exposure standards in effect
International: Transport as hazardous material under IATA, IMDG, ADR rules
Labelling: GHS-compliant pictograms and hazard statements required on all containers
Restrictions: Manufacturing, use, distribution, and disposal standards enforced to minimize exposure and prioritize environmental protection
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