Product Name: 1-Propanol, 2-Chloro-, (2S)-
Synonyms: (S)-2-chloro-1-propanol, S-2-Chloropropan-1-ol
CAS Number: 42153-54-2
Recommended Use: Laboratory chemical, chemical intermediate
Supplier Information: Manufacturer or distributor address and contact number
Emergency Contact: Local emergency phone number, Chemtrec or equivalent
Hazard Classifications: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye damage, Specific target organ toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed or inhaled, Causes serious eye irritation, Causes skin irritation
Pictograms: Exclamation mark, corrosion
Precautionary Statements: Avoid breathing dust, mist, vapors, Wash contacted skin thoroughly, Wear protective gloves, clothing, eye and face protection
Chemical Name: 1-Propanol, 2-Chloro-, (2S)-
Concentration: >99%
Impurities: Trace organic material, less than 1% other functional hydrocarbons
CAS Number: 42153-54-2
Inhalation: Move person to fresh air, keep comfortable and provide oxygen if needed, seek medical attention for persistent symptoms
Skin Contact: Immediately wash with plenty of soap and water, remove contaminated clothing, seek medical attention for irritation or burns
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice
Most Important Symptoms: Respiratory irritation, burning sensation, redness, coughing, eye watering, skin redness
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam
Unsuitable Extinguishing Media: Water jet (may spread fire)
Specific Hazards: Releases toxic fumes including hydrogen chloride and phosgene at high temperatures
Protective Equipment for Firefighters: Full protective suit, self-contained breathing apparatus
Firefighting Procedures: Approach fire from upwind, prevent runoff, cool exposed containers with water spray
Personal Precautions: Evacuate area, ensure adequate ventilation, wear protective equipment
Environmental Precautions: Prevent entry to sewers and waterways, report spillage
Cleanup Methods: Absorb with inert material like sand or vermiculite, collect into suitable containers for disposal, ventilate area thoroughly, wash contaminated surfaces to remove any residues
Precautions for Safe Handling: Use in a well-ventilated area, avoid inhaling vapors, prevent exposure to eyes, skin, and clothing, wash hands thoroughly after handling, keep away from heat sources and ignition
Storage Conditions: Store in tightly closed containers in cool, dry, well-ventilated areas, segregate from oxidizers, acids, and foodstuffs, store away from incompatible materials, label containers clearly
Technical Measures: Use explosion-proof electrical equipment and proper grounding for flammable chemicals
Occupational Exposure Limits: No established OSHA or ACGIH exposure limit for this compound; use lowest feasible exposure
Engineering Controls: Chemical fume hood or local exhaust ventilation
Personal Protective Equipment: Chemical safety goggles, suitable gloves (nitrile, neoprene), lab coat, full-length clothing, respiratory protection if ventilation is insufficient
Hygiene Measures: Remove and wash contaminated clothing, do not eat or drink near chemicals, wash hands before eating or smoking
Appearance: Clear colorless liquid
Odor: Pungent, reminiscent of chlorinated hydrocarbons
Odor Threshold: Not established
pH: Not applicable
Melting Point/Freezing Point: -40°C (estimate)
Boiling Point: 152–155°C
Flash Point: 70°C
Evaporation Rate: Not established
Flammability: Combustible liquid
Vapor Pressure: Low at ambient temperature, increases with heat
Vapor Density: Heavier than air
Solubility: Soluble in water, miscible with many organic solvents
Partition Coefficient: Not available
Autoignition Temperature: Not determined
Decomposition Temperature: Decomposes above 250°C
Viscosity: Moderately viscous at room temperature
Chemical Stability: Stable under recommended storage and handling conditions, sensitive to moisture, heat, and ignition sources
Reactivity: Reacts with strong acids, oxidizers, and alkali metals
Possibility of Hazardous Reactions: Polymerization not expected, may form hazardous gases in extreme conditions
Conditions to Avoid: Contact with water, spontaneous ignition possible with incompatible materials, heating
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through the skin; estimated oral LD50 for rats around 300 mg/kg
Skin Irritation: Moderate irritation and possible burns with prolonged exposure
Eye Irritation: Causes severe eye damage
Respiratory Effects: Inhalation leads to coughing, difficulty breathing, respiratory tract irritancy
Chronic Effects: Repeated exposure causes dermatitis, possible liver and kidney damage, no clear evidence of carcinogenicity
Sensitization: Data insufficient, but related compounds may sensitize skin
Aquatic Toxicity: Harmful to aquatic life, LC50 (fish) < 100 mg/L
Persistence and Degradability: Moderately biodegradable, breaks down in aerobic conditions
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: High mobility, may reach groundwater
Other Adverse Effects: Potential for local environmental impact near spill sites, follow precautions to minimize releases
Waste Treatment Methods: Dispose by incineration at approved facility, avoid landfill where possible
Contaminated Packaging: Triple rinse containers, treat washings as hazardous chemical waste, recycle if possible
Special Precautions: Prevent release to the environment, consult local, national, and federal waste regulations before disposal
UN Number: UN3276
Proper Shipping Name: 1-Chloro-2-propanol
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels Required: Toxic
Special Transport Precautions: Keep containers tightly closed, ship in upright position, avoid handling near food or feed, ensure correct documentation accompanies shipment
TSCA Status: Listed or subject to significant new use notification
REACH Status: Registered or exemption may apply based on use
OSHA: Considered hazardous chemical under 29 CFR 1910.1200
WHMIS (Canada): Classified as hazardous material
SARA Title III: Not known to be an extremely hazardous substance, not on Section 313 list
Other Regulations: Observe all local, state, and federal regulations relevant to chemical handling, storage, transport, and environmental protection
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