Product Name: 1-Chloro-2-propanolphosphate(3:1)
Other Names: Phosphoric acid, mono(chloroisopropanol) ester
Recommended Use: Flame retardant, intermediate for chemical synthesis
Manufacturer: [Manufacturer name]
Contact Information: [Address], [Emergency Phone Number], [Email for SDS requests]
CAS Number: 35677-40-4
GHS Classification: Acute toxicity (oral, dermal, inhalation), skin and eye corrosion, environmental hazard (aquatic acute/chronic)
Pictograms: Skull and crossbones, exclamation mark, corrosion, aquatic toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed, in contact with skin, or inhaled. Causes severe skin burns and eye damage. Toxic to aquatic life with long lasting effects.
Precautionary Statements: Avoid release to the environment. Wear protective gloves, clothing, eye, and face protection. Do not breathe dust or mist. Wash thoroughly after handling. If on skin, remove contaminated clothing and rinse skin.
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Target Organs: Eyes, skin, respiratory system
Chemical Identity: 1-Chloro-2-propanolphosphate(3:1)
CAS Number: 35677-40-4
PURITY: Typically >98%
Impurities: May contain minor amounts of related phosphoric acid esters, water, and unreacted isopropanol
Synonyms: TCPP; Tris(1-chloro-2-propyl) phosphate
Molecular Formula: C9H18Cl3O4P
Molecular Weight: 327.6 g/mol
Inhalation: Move victim to fresh air immediately. Seek medical attention if symptoms occur. Administer oxygen if breathing is difficult.
Ingestion: Do not induce vomiting. Rinse mouth with water. Get immediate medical attention.
Skin Contact: Remove contaminated clothing and shoes. Rinse affected area with plenty of water for at least 15 minutes. Use soap if possible. Seek medical advice.
Eye Contact: Rinse eyes with water for 15 minutes, lifting eyelids occasionally. Remove contact lenses if present and easy to do. Seek urgent medical help.
Notes for Doctor: Symptoms may be delayed. Provide symptomatic treatment and supportive care as needed.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, or water spray
Hazards from Combustion: Produces toxic gases including hydrogen chloride, phosphoric acid fumes, and oxides of carbon
Special Firefighting Procedures: Firefighters must wear self-contained breathing apparatus and full protective gear
Specific Hazards: Containers can burst under fire conditions. Runoff from firefighting may pollute waterways
Explosion Data: Does not present explosive risk under normal use, but thermal decomposition can cause pressure build-up in closed containers
Additional Info: Cool exposed containers with water spray to prevent rupture
Personal Precautions: Use appropriate personal protective equipment including gloves, chemical resistant eyewear, and respirators
Environmental Precautions: Prevent spillage from entering drains, soil, or waterways
Methods for Containment: Contain spill with inert materials such as sand, earth, or vermiculite
Cleanup Methods: Collect residue with non-sparking tools and transfer to secure containers for disposal. Wash spill site after material pickup.
Reference to Other Sections: Use information from Section on Exposure Controls and Personal Protection for minimizing risk during cleanup
Decontamination: Ventilate area after cleanup to dissipate vapors
Precautions for Safe Handling: Work in a well-ventilated area. Avoid contact with skin, eyes, and mucous membranes. Wear protective clothing. Do not eat, drink, or smoke while handling.
Incompatibilities: Avoid contact with strong oxidizers, strong acids, and strong bases
Conditions for Safe Storage: Store in tightly closed original containers in a cool, well-ventilated, and dry place away from sources of ignition and direct sunlight
Technical Measures: Drums and larger containers should have secondary containment
Storage Temperature: Stable under ambient temperatures, but prolonged exposure above 40°C can increase risk of decomposition
Other Notes: Label all containers clearly. Restrict access to trained personnel.
Occupational Exposure Limits: Not listed by OSHA, ACGIH, or NIOSH. Recommend minimizing exposure as no safe threshold has been established.
Engineering Controls: Use local exhaust or process enclosures to minimize vapor or aerosol generation
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles, lab coat, and splash apron
Respiratory Protection: NIOSH-approved respirators during spray or aerosol operations
Hygiene Measures: Wash hands thoroughly after handling; remove contaminated clothing; launder before reuse
Environmental Controls: Monitor workplace air. Employ spill control and secondary containment.
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild characteristic odor
Odor Threshold: Not established
pH: Not determined, typically acidic
Melting/Freezing Point: Decomposes before melting
Boiling Point: 244°C at 101.3 kPa
Flash Point: >200°C (closed cup)
Evaporation Rate: Not available
Flammability: Not easily combustible
Vapor Pressure: Very low at room temperature
Vapor Density: Greater than air
Specific Gravity: Approximately 1.28 (20°C)
Solubility: Slightly soluble in water; miscible with acetone, ethanol
Partition Coefficient (Log Kow): Estimated 2.6
Auto-ignition Temperature: Not determined
Decomposition Temperature: >260°C
Viscosity: 60-80 mPa·s at 25°C
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reacts with strong oxidizing agents, acids and bases
Hazardous Reactions: Decomposition above 260°C produces toxic gases such as hydrogen chloride and phosphoric acid fumes
Conditions to Avoid: Excess heat, incompatible materials, moisture and direct sunlight
Hazardous Decomposition Products: Phosphoric acid, hydrogen chloride, carbon monoxide, carbon dioxide
Polymerization: No hazard of polymerization expected
Acute Toxicity (oral): LD50 (rat) > 500 mg/kg; can cause gastrointestinal upset, burns, and systemic effects
Acute Toxicity (dermal): LD50 (rabbit) > 2,000 mg/kg; may cause chemical burns
Acute Toxicity (inhalation): Data limited; vapors or mists may irritate respiratory tract and mucous membranes
Skin Corrosion/Irritation: Causes severe skin irritation or chemical burns on prolonged contact
Eye Damage/Irritation: Causes severe eye damage, possible blindness
Respiratory Sensitization: Prolonged exposure may increase risk of respiratory irritation; no evidence of sensitization
Germ Cell Mutagenicity: Data inadequate for classification
Carcinogenicity: Not classified by IARC, NTP, or OSHA as a known carcinogen
Reproductive Toxicity: No evidence based on available data
Specific Organ Toxicity—Single Exposure: May affect respiratory and digestive systems
Specific Organ Toxicity—Repeated Exposure: Chronic contact may cause dermatitis, respiratory tract irritation
Aspiration Hazard: May be harmful if aspirated into the lungs during ingestion or vomiting
Toxicity to Aquatic Organisms: Highly toxic to aquatic life, LC50 (Fish, 96hr): 10–100 mg/L
Persistence and Degradability: Not rapidly biodegradable; persists in the environment
Bioaccumulative Potential: Moderate, accumulates in aquatic organisms (log Kow ~2.6)
Mobility in Soil: Has moderate mobility, some leaching expected
Other Adverse Effects: Alters aquatic ecosystems; caution advised to prevent release
Ecotoxicological Remarks: Take steps to avoid accidental contamination of soil and watercourses
Waste Treatment Methods: Incinerate in a chemical incinerator equipped with scrubbers
Disposal of Containers: Triple rinse and puncture before sending to approved recycler or licensed hazardous waste facility
Other Disposal Recommendations: Follow national, regional, and local regulations
Environmental Precautions: Do not discharge to sewers or natural water bodies; prevent significant releases
UN Number: 3082
UN Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (contains 1-chloro-2-propanolphosphate(3:1))
Transport Hazard Class: 9
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Ensure containers are tightly sealed and appropriately labeled
Emergency Response Guide: Refer to standard ERG for hazardous substances (ERG No. 171)
OSHA Status: Considered hazardous under defined criteria
TSCA: Listed on the U.S. Toxic Substances Control Act inventory
REACH: Registered substance in Europe; subject to authorizations and restrictions
SARA (Title III): Listed as hazardous; subject to reporting under Section 311/312
California Proposition 65: Not listed
Canadian DSL/NDSL: DSL listed
Other Regulations: Covered by applicable state, provincial, and international workplace safety guidelines
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