Product Name: 1-amino-2,3-propanediol
Synonyms: Serinol, 2,3-dihydroxy-1-aminopropane
CAS Number: 534-03-2
Recommended Use: Laboratory research, chemical synthesis, pharmaceutical intermediates
Supplier Details: Contact local supplier for emergency phone, address, and technical contact information
Emergency Phone Number: Refer to local guidelines or supplier’s emergency contact
GHS Classification: Irritant to eyes and skin, possible respiratory tract irritant
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; may cause skin irritation; causes respiratory irritation if dust inhaled
Pictograms: Exclamation mark
Precautionary Statements: Avoid inhalation of dust, wash skin thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves, clothing, and eye protection
Chemical Name: 1-amino-2,3-propanediol
Synonyms: Serinol
CAS Number: 534-03-2
Formula: C3H9NO2
Concentration: >98% (pure form for laboratory use)
Eye Contact: Flush eyes immediately with plenty of water for at least 15 minutes; remove contact lenses if possible; seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, rinse skin with soap and water; seek medical attention for persistent irritation or allergic reaction
Inhalation: Remove person to fresh air; keep at rest; seek immediate medical attention if respiratory symptoms develop
Ingestion: Rinse mouth with water if conscious; do not induce vomiting; seek medical advice
Most Important Symptoms and Effects: Redness, pain or irritation in eyes and on skin, coughing, difficulty breathing from dust exposure
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water mist, foam
Unsuitable Media: High-pressure water jet may cause spattering
Hazards from Combustion: Produces toxic fumes of nitrogen oxides and carbon oxides during fire
Protective Equipment: Use self-contained breathing apparatus and full protective gear in enclosed spaces
Special Procedures: Cool exposed containers with water spray; move containers away from fire if safe
Personal Precautions: Wear chemical-resistant gloves, goggles, and suitable respiratory protection
Environmental Precautions: Prevent run-off into drains, surface water, and soil
Methods for Containment and Clean Up: Avoid dust formation, sweep up and shovel material into a chemical waste container, use appropriate tools to minimize dust, ventilate area, wash spill site after material pickup is complete
Handling: Work in well-ventilated areas, avoid generation of dust, avoid direct contact with skin and eyes, use appropriate PPE, do not eat, drink, or smoke when using this chemical, wash thoroughly after handling
Storage: Store in a tightly closed, labeled container in a cool, dry, well-ventilated place, away from incompatible substances like strong oxidizers and acids, protect from moisture and direct sunlight, keep away from food and beverages
Engineering Controls: Use local exhaust ventilation or work in a chemical fume hood to minimize airborne concentrations
Personal Protection: Wear chemical safety goggles, lab coat, chemical-resistant gloves; use a dust mask or respirator if exposure limits are exceeded or dust formation is possible
Hygiene Measures: Remove contaminated clothing and wash before reuse; maintain good housekeeping to prevent buildup; do not touch face or eyes during use
Appearance: White to off-white crystalline solid
Odor: Slight, amine-like
Molecular Weight: 91.11 g/mol
pH (10% aqueous solution): Approximately 7-9
Melting Point: 72–75°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water and ethanol, slightly soluble in acetone
Density: 1.24 g/cm³ at 20°C
Vapor Pressure: Negligible at room temperature
Flash Point: >100°C (closed cup)
Chemical Stability: Stable under normal laboratory and storage conditions
Conditions to Avoid: Moisture, heat, open flames, incompatible chemicals like strong oxidizing agents or acids
Incompatible Materials: Strong oxidizers, acids, acid chlorides
Decomposition Products: Nitrogen oxides, carbon monoxide, and carbon dioxide
Hazardous Reactions: No hazardous polymerization reported
Acute Toxicity: Low acute toxicity, but exposure to high concentrations of dust can irritate mucous membranes and respiratory system
Skin Corrosion/Irritation: Mild to moderate irritant in sensitive individuals
Serious Eye Damage/Irritation: Causes significant eye irritation on exposure
Respiratory Sensitization: No data available on sensitization, use caution for those with airways sensitivities
Chronic Effects: Prolonged or repeated exposure may cause skin dryness or cracking, persistent respiratory irritation
Carcinogenicity/Mutagenicity: No data suggest carcinogenic or mutagenic risks under normal handling
Aquatic Toxicity: Not classified as acutely toxic to aquatic life, but avoid large discharges to waterways
Persistence and Degradability: Biodegradable in the environment under normal biological conditions
Bioaccumulative Potential: Low potential for bioaccumulation based on molecular structure
Mobility in Soil: Expected to move rapidly through soil due to water solubility
Other Adverse Effects: No known significant environmental hazards at laboratory-scale quantities
Waste Handling: Collect and containerize spilled materials for proper disposal
Disposal Method: Dispose of as hazardous chemical waste, comply with local, regional, and national regulations
Contaminated Packaging: Triple rinse containers, then offer for incineration or recycling if possible; avoid contaminating recycling streams
UN Number: Not assigned
Hazard Class: Not regulated as dangerous goods for transport under most local or international guidelines
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Secure containers to prevent accidental spills or handling during transport; store away from food and animal feed during transit
EU Classification: Not specifically classified, observe general chemical safety standards
TSCA Status (USA): Appears on the TSCA inventory
DSL/NDSL (Canada): Listed on Canadian DSL
REACH Status (Europe): Some uses may require registration; consult supplier to confirm compliance
Other Regulations: Follow workplace safety regulations, chemical hygiene plans, and waste management rules as set by local authorities
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