Chemical Name: 1,3-Propanediol di-p-toluenesulfonate
Synonyms: 1,3-Propanediol ditosylate, Tosylated propanediol
CAS Number: 2162-56-1
Recommended Use: Intermediate in organic synthesis, specialty chemical manufacturing
Manufacturer: Chemical supply companies specializing in organic intermediates
Emergency Contact: Refer to local poison control, emergency services for chemical handling
Product Code: Specific to supplier, often indicated on label and invoice
Classification: Irritant to eyes, skin, and respiratory tract; Combustible solid
GHS Label Elements: Exclamation mark symbol, warning for irritation\n
Hazard Statements: Causes skin and eye irritation; May cause respiratory tract irritation
Precautionary Statements: Wear gloves, goggles; Use only in well-ventilated areas; Avoid breathing dust
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Potential Acute Effects: Redness, itching, coughing, possible nausea if inhaled or ingested
Long-term Effects: Prolonged contact may worsen irritation, possible dermatitis
Chemical Identification: 1,3-Propanediol di-p-toluenesulfonate
Formula: C17H20O6S2
Molecular Weight: 400.47 g/mol
Concentration: Purity often above 98% from reliable sources
Impurities: Trace water, unreacted tosyl chloride, minor by-products depending on synthesis
Additives: None typically added, product shipped as pure compound
Inhalation: Move person outside into fresh air, loosen tight clothing, seek attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash skin with soap, rinse with water; medical advice for irritation
Eye Contact: Rinse open eyes gently for several minutes, remove contact lenses, seek medical advice if necessary
Ingestion: Rinse mouth, do not induce vomiting, medical attention advised for discomfort or large ingestion
Most Important Symptoms: Itching, burning sensation on contact; coughing or difficulty in breathing upon inhalation; nausea after ingestion
Note: Medical staff should be informed of compound identity
Suitable Extinguishing Media: Dry chemical powder, CO2, water spray (small fires), foam for bigger incidents
Unsuitable Extinguishing Media: Direct jet of water may spread burning material
Hazards from Combustion: Releases toxic gases such as sulfur oxides, carbon monoxide, carbon dioxide, and toluene vapors
Protective Equipment: Self-contained breathing apparatus, chemical resistant clothing
Firefighters’ Advice: Approach upwind, prevent runoff into drains and water sources
Special Procedures: Cool containers with water if exposed to heat; remove material from fire area if safe
Personal Precautions: Evacuate unprotected persons, ventilate area, use appropriate PPE (gloves, goggles, mask)
Spill Cleanup: Collect spill using shovel or sweep, avoid raising dust, transfer to suitable container for disposal
Environmental Precautions: Do not allow product to enter drains, surface water, or soil; contain any run-off
Decontamination: Wash area with water and mild detergent after removal, dispose contaminated materials as chemical waste
Safe Handling Advice: Use in fume hood, open containers carefully, avoid dust generation, keep away from strong acids/bases
Storage Conditions: Store in tightly closed original containers, in cool, dry and well-ventilated place
Segregation: Keep away from incompatibles such as strong oxidizers
Hygiene Practices: Wash hands thoroughly after handling, do not eat or drink during use
Occupational Exposure Limit: No established specific limits, minimize exposure as much as possible
Engineering Controls: Local exhaust ventilation, chemical fume hood, avoid aerosol generation
PPE: Chemical-resistant gloves (nitrile recommended), splash goggles, lab coat; use respirator if dust cannot be avoided
Environmental Controls: Avoid discharge into environment, use closed systems or adequate ventilation
Appearance: White-hued crystalline solid
Odor: Little to no detectable smell
Melting Point: Ranges 103°C to 106°C
Boiling Point: Not easily volatile at standard atmospheric pressure
Solubility: Slightly soluble in water, readily soluble in organic solvents (acetone, ethanol)
Density: Approximately 1.36 g/cm³
pH: Neutral to slightly acidic in aqueous suspension
Vapor Pressure: Negligible at room temperature
Partition Coefficient: Not readily available, expected to favor organic phase
Stability: Stable at room temperature, avoid exposure to heat, moisture
Reactivity: May react with strong oxidizers, bases
Conditions to Avoid: High humidity, open flames, strong alkalis, strong acids
Hazardous Decomposition: Sulfur oxides, toluene, possible acrid smoke on decomposing
Acute Toxicity: Low for small quantities based on structural analogs; actual LD50 not well-established
Irritation: Causes irritation to skin, eyes, mucous membranes
Sensitization: No well-documented evidence of skin or respiratory sensitization
Chronic Effects: Prolonged contact could aggravate pre-existing skin disorders
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Other Effects: Risk of minor gastrointestinal discomfort on ingestion, not expected to be systemically toxic in small accidental exposures
Aquatic Toxicity: Limited data, structurally similar compounds display moderate toxicity toward aquatic organisms
Environmental Fate: May not degrade rapidly in environment; persistence likely in sediment due to low water solubility
Bioaccumulation: Not expected to bioaccumulate significantly, but caution recommended in case of spills
Mobility in Soil: Low mobility because of low water solubility; contamination risk near chemical storage areas
Other Hazards: Avoid uncontrolled release to prevent concentration in water bodies that harm aquatic ecosystems
Waste Treatment Methods: Collect as hazardous organic chemical waste, incineration in controlled facilities recommended
Contaminated Packaging: Containers should be rinsed, disposed according to local and national regulations
Special Precautions: Do not discharge to sewer, surface water, or soil; contact licensed waste disposal contractor
Regulatory Requirements: Follow hazardous waste labeling, transport, and storage requirements to protect handlers and environment
UN Number: Not assigned; not classified as dangerous goods under most transport regulations
Transport Hazard Class: Not regulated, but professional packaging and marking still needed
Packing Group: Not assigned
Environmental Hazards: Product may pose risk to aquatic environments on large releases
Additional Precautions: Ensure packaging prevents leaks, clearly label contents; store upright, handle gently to avoid spills during shipping
OSHA Status: Not specifically listed under OSHA hazardous chemicals
TSCA Inventory: Compound typically listed or eligible in the US TSCA inventory
REACH Registration: Subject to registration and notification in the EU if manufactured or imported above threshold
Labeling Requirements: Follow workplace chemical labeling rules; GHS labeling includes signal word and hazard pictogram
Other Local Regulations: Hazard communication standards, environmental emission limits can apply; always check latest updates for country of use
Worker Training: Employers should train workers in safe handling and emergency response for chemicals in this category
Providing high-quality chemical products and logistics solutions for global trade partners.
