1,3-Propanediol, 2-ethyl-2-methyl- (8CI)(9CI): A Closer Look

Historical Development

Chemistry, as a field, thrives on small steps that turn into big breakthroughs. Take 1,3-Propanediol, 2-ethyl-2-methyl- for instance. Its roots trace back to the mid-20th century, not long after research into diols gained momentum because folks wanted new precursors for polymer synthesis and specialty solvents. Scientists started poking around diol variants, looking for unique side chains to influence flexibility, temperature tolerance, and volatility. The early syntheses borrowed from petroleum chemistry, stringing together base hydrocarbons with precise catalytic controls. The first notable laboratory records outlining this specific compound popped up in patent filings through the 1970s, riding the wave of expanding plastics and performance chemicals. By the 1990s, the landscape changed with a growing appetite for specialty chemicals catering to coatings, resins, and pharmaceutical intermediates. Today, production sits quietly within custom manufacturing plants, ready to serve chemists seeking special properties.

Product Overview

Ask a process chemist about 1,3-Propanediol, 2-ethyl-2-methyl-, and you’ll get that half-smile; they know it doesn’t make headlines, but it’s a workhorse in labs and plants where precision matters. It sports a quirky, branched backbone—a main carbon chain with two functional diol groups and extra methyl and ethyl groups hanging from the center carbon, introducing a steric kink. This shape influences solubility, reactivity, and how it interplays with other ingredients. Demand often comes from research chemists working on new resins or plasticizers; sometimes it shows up in specialty coatings and flavor synthesis. It rarely stands alone but usually steps in as a modifier to tweak reactivity, plasticity, or thermal resistance in finished products. It sits on the shelf next to more famous diols but comes off when unique branching makes a difference in final performance.

Physical & Chemical Properties

1,3-Propanediol, 2-ethyl-2-methyl- presents as a clear, slightly viscous liquid under normal lab conditions. Its molecular formula, C6H14O2, points to a moderately heavy but still manageable chemical—no extremes here. The boiling point hovers between 200-210°C, depending on atmospheric pressure and minor impurities, giving it some edge in both processing and storage. It dissolves gently in water but likes alcohols or ethers much better thanks to its carbon-rich structure. Its two hydroxyl groups encourage hydrogen bonding, though that extra branching on the central carbon meddles with standard patterns of association. In direct handling, the compound acts predictably as a secondary alcohol, participating in dehydration and esterification without throwing curveballs.

Technical Specifications & Labeling

Manufacturers list purity in the fine print, with high-grade batches (98% and up) used in R&D or pharmaceutical settings. Impurities—usually water, nearby diol isomers, or traces of the starting hydrocarbon—can change performance, especially in polymerization or catalytic processes. Labels cite the IUPAC name, CAS number (if registered), and all relevant safety pictograms, often emphasizing storage away from oxidizers and sources of heat. Regulatory agencies may ask for testing documentation, with key certificates like GC-MS spectra stapled to shipping documents for higher oversight. Given increasing calls for traceability in chemical sourcing, buyers demand clear batch history and proof of consistent methods. This isn’t an off-the-shelf item at every chemical supplier, so those who stock it stand ready with paperwork just as much as barrels.

Preparation Method

Synthetic routes begin with carbon chain assembly—a careful alkylation of propanediol skeletons, guided by catalysts that encourage the right branch at carbon-2. Classic methods favor Grignard reagents or organolithium intermediates to slap on the methyl and ethyl, followed by selective reduction and dehydration cycles to control unwanted byproducts. Yields swing with fine-tuned temperature, solvent polarity, and the timing of each step; run too fast, and side reactions crowd the product. Some protocols draw from renewable feedstocks using bioprocesses, especially among specialty green chemical suppliers chasing sustainable synthesis. Purification calls for vacuum distillation or liquid-liquid extraction, all under the hood of a ventilated fume cupboard. The complexity of this compound’s assembly leaves little room for shortcuts.

Chemical Reactions & Modifications

Chemical hands appreciate how this compound behaves—it plays well in esterification reactions with acids, opening paths to polyesters and specific surfactants. The secondary alcohol on carbon-2 gives an entry point for selective oxidation, sometimes turning it into a ketone when the application calls for further functionalization. Under strong acid catalysis, it facilitates ring closure or acts as a nucleophile in carbonyl condensations. In recent years, research lines explored crosslinking reactions, using it to bridge polymer chains and add resilience to specialty rubbers or thermosetting resins. While its reactivity mostly lines up with expectations from a diol, the shape and branch length present unique kinetic patterns, making reaction rates and equilibrium positions something you learn by experiment, not just textbook theory.

Synonyms & Product Names

Specialty chemicals circulate under more names than a traveling musician. For 1,3-Propanediol, 2-ethyl-2-methyl-, suppliers might call it 2-Ethyl-2-methyl-1,3-propanediol, or use trade names cooked up by marketing teams hungry for distinction. In some catalogs, it hides under less formal lab shorthand like “branched propanediol 2-2.” Chemists who lean on abbreviations scribble something like “EMPD” into their notebooks. Buyers and procurement departments double-check CAS numbers to sidestep confusion, because the diagram on the bottle tells the truest story.

Safety & Operational Standards

Safety sheets for 1,3-Propanediol, 2-ethyl-2-methyl- echo standard protocols for glycol-like compounds: gloves, splash goggles, and good ventilation. While not a notorious toxin, its structure asks for smart handling—skin contact causes irritation in some, and inhaling a fine mist, even once, warns the lungs. Spills mean wiping down with absorbent pads and quick disposal according to hazardous waste guidelines. The compound isn't famous for explosive or reactive risks, so typical flammable-storage rules apply. Companies with cleanroom packaging get the upper hand, preventing dust or airborne contaminants from clinging to viscous drops. In larger-scale plants, closed-system pumps and automated valves cut down on exposure—a detail that OSHA inspectors always notice. Emergency plans build in appropriate neutralizing agents for any leaks or splatter incidents.

Application Area

Not every lab stocks this compound, but the ones that do tend to value its nuances. Resin developers test it for branching polymers where core flexibility sharpens thermal characteristics. It lands in select adhesives and coatings, sometimes in formulations meant to push water resistance or add subtle plasticity without leaning on more common glycols. In flavors and fragrances, the unique skeleton can help synthesize intermediates needed for specialty notes. Crop science researchers play with it too, looking for starter compounds to create fresh agrochemicals with updated safety margins. Pharmaceutical formulation keeps an eye on it; some prodrugs need diol-based linkers with bulkier side groups to change solubility or degradation rates. This isn’t the workhorse like standard 1,3-propanediol, but gets its day in the sun during innovation cycles.

Research & Development

Research into 1,3-Propanediol, 2-ethyl-2-methyl- keeps rolling, mostly in industrial chemistry and select life sciences. Teams working on next-gen polymers try to harness its peculiar backbone for smarter materials, especially where existing glycols leave gaps. Green chemistry labs dig into new biosynthetic routes, aiming for higher yields from yeast or bacterial hosts to trim petrochemical dependence. Analytical chemists want better methods to track trace impurities—a detail that matters in pharma and medical device fields. Intellectual property filings increase as novel end-uses for branched diols emerge—whether as plasticizer alternatives or as building blocks for surfactants. University groups probe structure-reactivity relationships, learning how slight shifts in branching play into final material toughness, resilience, or degradation speed. Growth in demand shows up most clearly during patent bursts and expansion in pilot plant orders.

Toxicity Research

Toxicology sits center-stage during any push to widen use. For 1,3-Propanediol, 2-ethyl-2-methyl-, studies point to low acute toxicity, echoing findings seen with other branched diols. Repeated skin exposure over weeks brings on irritation in sensitive test groups, and long-term inhalation carries mild risks but stays far less problematic than solvents like toluene. Metabolite mapping in animal models finds the compound breaks down to simpler alcohols and organic acids, building a safety argument for use in controlled environments. That said, chronic effect data remains sparse, prompting calls for more thorough screening before considering widespread food or medical-grade adoption. Environmental breakdown profiles look promising—microbes decompose it within standard wastewater treatments, though some byproducts beg further analysis for eco-tox risks. Labs and regulatory bodies keep updating standards and stretch for better dermal and inhalation exposure models.

Future Prospects

The chemical world moves based on market shifts, regulatory windows, and breakthroughs spun out of university labs. As performance materials enter the spotlight and circular economies push for greener, safer feedstocks, 1,3-Propanediol, 2-ethyl-2-methyl- has a ticket to bigger markets. If current biosynthetic experiments deliver higher-yield processes at scale, this diol stands to replace bulkier, less manageable glycols in specialty plastics and coatings. Trends in custom pharmaceuticals and agrochemicals often require precise backbone tailoring, opening new doors for derivatives and modified forms of this core structure. Companies committed to reducing environmental footprints keep scouting alternatives that mix performance with biodegradability—the unique branching in this compound may hold answers to challenges polymer engineers have wrangled for decades. The next big leap likely comes from intersecting better catalysis with bioprocessing, shaving off costs and letting volume producers meet the growing specialty demand.



What are the main applications of 1 3-Propanediol 2-ethyl-2-methyl- (8CI)(9CI)?

From Industry Floors to Lab Benches

1,3-Propanediol 2-ethyl-2-methyl- does not get much limelight outside the technical world, but its presence stretches across several industries. At the core, this compound pops up as a fundamental ingredient or intermediate when companies want both reliability and flexibility. Anyone who has worked in a chemical manufacturing plant will tell you: efficiency and predictability mean everything, and this compound brings both to the table.

Polymer Production and Beyond

This glycol derivative ranks highly among building blocks for polyester and polyurethane manufacturing. Factories invest in it to ensure durable fibers and resins, since it encourages tough bonds between molecules—the sort of property that leaves clothing more resilient and coatings less prone to cracking. Polymers based on 1,3-Propanediol blends now appear in automotive interiors, sporting goods, and even flooring. These uses matter because the world cannot rely forever on petrochemicals that pollute. Sourcing ingredients with a better environmental profile means downstream products may become safer, lighter, and longer-lasting.

Cosmetics and Personal Care

Not all chemical compounds can touch skin safely, but plenty of researchers trust this diol derivative in cosmetics. Its low toxicity and smooth solubility make it an anchor in lotions, creams, and hair products. As a co-solvent, it keeps ingredients evenly mixed and helps the final product soak in quickly. Anyone who’s worked behind the scenes in a cosmetics company knows how little product instability the market will tolerate—bad batches can cost millions. Having a reliable base chemical dramatically reduces headaches on the production line.

Solvents and Industrial Fluids

Often, industries turn to 1,3-Propanediol 2-ethyl-2-methyl- when searching for new solvents. Traditional solvents tend to be harsh or hazardous—just ask laboratory technicians dealing with constant headaches from old-school options. This compound’s better human and environmental safety profile means less risk for workers and lower compliance costs. New formulations of inks, paints, and lubricants can now drop the more toxic options and put safety first. In green chemistry, small steps like this add up: they let factories shrink their environmental footprint without forcing tough trade-offs in performance.

Pharmaceutical Intermediates

Drug development calls for reliable intermediates. This chemical serves as an intermediate or even a stabilizer for medication synthesis, where side-reactions could ruin the purity of an expensive batch. Companies taking shortcuts on purity face recalls that damage trust and put patients at risk. Having dependable chemical building blocks matters not just for profits, but for public health.

The Search for Better Practices

Larger chemical companies still lean heavily on oil-based sources. Newer developments show ways to make compounds like 1,3-Propanediol 2-ethyl-2-methyl- using fermentation, rather than cracking crude oil. This effort matters if industry wants a future where production lines run on something more sustainable than fossil fuels. Continued research and tighter regulations can nudge companies to keep improving, but real progress takes open collaboration across the chemical supply chain.

Is 1 3-Propanediol 2-ethyl-2-methyl- (8CI)(9CI) hazardous or toxic?

Chemicals in Everyday Life

Chemicals like 1 3-Propanediol 2-ethyl-2-methyl- often work behind the scenes in products people use every day. This particular substance pops up in industrial settings, such as manufacturing plastics or specialty coatings. Most folks may never come into direct contact with it, but that doesn’t mean it should be ignored. From past experience, even chemicals that sound obscure can impact workers, neighbors of facilities, and the environment.

Reading the Research on Toxicity

Digging into the research, there's not much public data on large-scale effects of 1 3-Propanediol 2-ethyl-2-methyl-. Safety information in official safety data sheets leads with phrases like "avoid contact with skin and eyes" and "use with indoor ventilation." That usually signals possible risks, even if they don’t spell out disaster. Chemicals like this often get classified as irritants. Lab tests on similar compounds have shown that contact with skin or inhaling their vapor can lead to redness, irritation, or even headaches.

Long-term risks sometimes only turn up years after a chemical enters the market. Think of solvents like toluene and xylene. Those didn’t draw much attention in their early days, but later became linked with organ toxicity and neurotoxicity after problems stacked up in exposed workers. Experience shows it pays to watch these chemicals early. Using gloves and protective masks, plus good ventilation, provides basic safety for workers.

Why Everyday Exposure Matters

It’s tempting to shrug off a name that long. Still, stories pile up about factory employees facing chronic irritation, struggling with lung problems, or carrying health worries home. I’ve seen shop floor staff ready to swap shifts to avoid certain lines—exposure adds up, even if a substance isn’t officially marked as “toxic.” The EPA and OSHA rely on good company data to track chemicals. Gaps in records happen, and sometimes it takes years to see a pattern.

A big question for many chemicals isn’t just their direct toxicity—it’s their breakdown products. The stuff released during a spill or fire can turn nastier than the original ingredient. Companies that store or use 1 3-Propanediol 2-ethyl-2-methyl- would be smart to keep spill plans and eye wash stations nearby, no matter what a chart says.

How to Tackle Uncertainty

People who handle unknown chemicals face a trade-off: chasing productivity while protecting health. In my own workshop days, it was the old habits—handwashing, wearing gloves, and checking the label twice—that held up when a new drum showed up. Every unknown deserves a quick check for Material Safety Data Sheets and a few questions to suppliers.

Stronger transparency could help here. Pushing for independent research, not just company-funded studies, brings out missing data. Community right-to-know laws empower neighbors to ask about potential risks before smells or illnesses start.

Better Precautions, Fewer Surprises

Hazards with unfamiliar chemicals rarely show up overnight. Routine monitoring and smart substitution—switching to a better-known or less-reactive ingredient—help prevent unwanted surprises. Teams with real experience managing workplace safety serve as the best line of defense. Companies that treat each “new” chemical with respect tend to face fewer emergencies down the road.

What are the storage and handling recommendations for this chemical?

Getting Serious About Chemical Storage

Working in labs taught me early on that chemicals never forgive sloppy storage. Walk into a facility, and the way bottles sit on shelves tells you everything. Strong-smelling acids near steel lockers? That’s trouble waiting. Flammable solvents next to electrical outlets? Someone didn’t read the manual. Harsh lessons from fires or ruined experiments underscore something simple: storage isn’t a paperwork drill. It can make the difference between a quiet shift and a big mess.

Choosing the Right Room and Setup

Chemicals like cool, dry spots. Average classrooms don’t cut it. Spaces with temperature swings, leaking roofs, or bad light turn storage into a gamble. I’ve seen glass jars sweat and labels smear after a humid night — what’s in the bottle? Without the right environment, guessing becomes part of the job.

Ventilation matters. A cramped cabinet with sealed doors traps fumes. Open it, and out comes a cloud of trouble. Good storage spaces feature clear labels, solid ventilation, and lighting that lets you spot damage or leaks. It only takes one cracked bottle to shut down a wing.

Containers and Labeling

Glass, metal, plastic — these all play a role, if they fit the job. Acids eat through cheap metal. Solvents chew up certain plastics. Skipping the right container ends up in slippery puddles, wasted product, or worse, injuries. In many labs, I’ve relied on thick-walled glass or lined metal drums for nasty stuff. The label needs to stay put, readable even after a spill. Faded handwriting or peeling stickers create guesswork, and no one wants that when time matters.

Segregation: Keep Enemies Apart

One section for acids, another for bases, oxidizers walking their own lonely aisle. Good habits come from stories, not rules. I watched a friend open a cabinet that mixed bleach with ammonia; fumes sent him running for a mask. Those mistakes cost hours, sometimes lives. Keeping chemicals sorted turns big accidents into minor annoyances.

Training and Oversight

Reading an SDS is one thing, but watching an old hand handle sodium for the first time teaches more. In facilities with regular drills and honest conversations, accidents drop. No one should fear admitting they knocked over a flask. Encouraging that culture keeps everyone sharp, tickets fewer, and insurance less painful.

Compliance with regulations isn’t about avoiding fines — it means sticking to routines proven to keep folks out of the ER. The Environmental Protection Agency, OSHA, and local fire codes list standards for storage and handling. Real harm happens when people treat those rules as paperwork instead of protection.

Emergency Plans: Hope for the Best, Expect the Worst

Even the best plans go sideways. A chemical splash, a spill, or broken glass puts nerves to the test. An eyewash station within reach, fresh absorbents close by, and escape routes marked in bright tape – these aren’t just decor. I’ve seen workers waste precious seconds hunting for spill kits. Every minute counts with toxic leaks.

Making Smart Next Steps

Choosing the right storage isn’t hard, but following through takes grit. Leadership sets the tone. No shortcut replaces regular audits, mixing up storage maps, or double-checking shelf life. In the end, safety isn’t a fixed state; it demands stubborn attention — and a little bit of humility.

Are there any specific safety precautions when working with this product?

Understanding the Risks Isn’t Optional

Lots of folks jump into using a new product without reading the label. That’s where accidents begin. Every chemical—whether for home or industrial use—carries its own set of risks. I’ve seen cases where a “common” household cleaning solution left someone with chemical burns because they worked bare-handed. There’s no substitute for personal experience, but you don’t want that experience to include a trip to the ER.

Protective Gear Is Non-Negotiable

Gloves matter. Not those thin plastic ones you get with hair dye, but ones built for protection against specific chemicals. Dug deep enough into safety datasheets, and you’ll learn there’s a difference between latex, nitrile, and heavy-duty rubber gloves. Same goes for eye protection—safety goggles beat out sunglasses every time. Respirators have their place. Anyone who’s ever spent an afternoon scrubbing mold knows the difference a mask makes for your lungs.

Ventilation Saves Lungs

One summer, I helped repaint an old shed with a solvent-based product. A friend of mine thought opening just one window would do. Fumes built up in minutes. If air moves freely, headaches, dizziness, and worse are much less likely. Fans and open doors make a difference, even on “quick” projects. Don’t trust your nose—if you can smell something sharp, your body already signals trouble.

Label Reading and Storage—Small Steps, Big Impact

Labels on chemical products are not marketing fluff. The warnings printed in bold letters exist for a reason. One missed symbol, and you might store something flammable beside a heat source or mix two products that don’t play well together. I once mixed bleach and ammonia by accident as a teenager, gassed myself out of the garage, and realized how fast a careless mistake turns serious.

Spills Happen—Know the Response

Even with the best planning, spills do happen. Quick thinking and knowing your product’s cleanup requirements can keep a small mess from becoming a disaster. Sand, absorbent pads, or simply lots of running water sometimes solve the problem—but only if you know ahead of time what works with what. For example, acids and caustics need different neutralizers. You don’t have to get fancy, but keeping basic supplies handy makes a real difference.

Keep Kids and Pets Out of the Mix

Children and animals turn up in places you least expect. Chemical storage needs to mean out of reach and out of sight. Locked cabinets or high shelves go a long way, especially in homes. I’ve seen neighbors lose pets to spills they swore were out of reach. If it’s dangerous for you, it’s even riskier for kids and animals who can’t read a warning label or shout for help.

Stay Informed—And Pass It On

Big companies train people on chemical safety for a good reason. At home, most people rely on old habits. If something new comes along, take ten minutes to read the instructions. Share solid tips with friends and family, and don’t downplay the risks. Respecting these products leads to fewer accidents, less pain, and more time spent doing what you enjoy instead of dealing with the aftermath of a preventable mistake.

What is the molecular structure or CAS number of 1 3-Propanediol 2-ethyl-2-methyl- (8CI)(9CI)?

Understanding the Structure and Naming

Science has a habit of assigning names that seem meant to confuse more than clarify, and chemical nomenclature is notorious for it. Take 1,3-Propanediol, 2-ethyl-2-methyl-. A mouthful that points to a molecule related to the every-day glycol family, but with a bit of branching on the central carbon. Its systematic name looks intimidating, but if you’ve spent any time in a lab or thumbed through a basic chemistry textbook, it starts to make sense. Picture a propane backbone—a simple three-carbon chain. Then hang hydroxyl groups on either end, at carbons one and three. The real twist: smack an ethyl and a methyl group both onto the central carbon. Chemists call this central carbon a gem-dialkyl carbon, literally because it's holding two different groups at once.

To put a fine point on it, this compound carries the CAS Number 115-84-4. The CAS (Chemical Abstracts Service) registry number acts like a digital fingerprint for molecules. Manufacturers, regulators, and researchers depend on this code to communicate with absolute precision. Any slip—say, mixing up the prefix or dropping a digit—can mean ordering the wrong compound, which costs time, money, and sometimes safety.

Why Precision in Chemical Identification Matters

I remember working with a team that once misread a similar name in procurement. Say goodbye to half the project budget—and say hello to a shipment of a near-identical but ultimately useless chemical. In labs and factories, misidentifying such a specific branched diol can throw a wrench straight into critical operations. In the pharmaceutical world, for instance, one atom out of place risks toxicity, inefficacy, or even regulatory nightmares. That’s where CAS numbers become invaluable: no room for guesswork, no chance for error.

Outside the lab, these identifiers drive broader trust. Investors want to know the compound is what it claims. Regulators require proof that a product entering the supply chain matches its documentation. This all trickles down to consumer safety, where traceability matters. Whether it goes into plastics, solvents, or even as an intermediate for something bio-based, tracking the stuff from cradle to grave only works with exact identifiers.

Tackling the Challenges: Transparency and Education

As chemistry moves further into the world of biobased and specialty production, the importance of clear chemical identification swells. More attention now lands on chemical transparency, pushed by movements for safer chemicals and more ethical sourcing. Without plain facts—like a CAS number or a proper molecular structure—downstream users stumble.

One real solution starts in education. Schools and training programs ought to push for more than rote learning of names. If students get to know why these structures and codes matter, and how missteps can ripple out to real health and environmental risks, the next generation of chemists grows more careful by default.

Industries could also demand better digital tracking. Scannable codes, full molecular structure diagrams, clear labeling at every step. Open databases where a glance tells you exactly which variant stands in front of you. All of this requires sharing knowledge and refusing to settle for "close enough."

Building Reliable Chemical Supply Chains

At its core, the 1,3-Propanediol, 2-ethyl-2-methyl- discussion isn’t just about getting a name right. It flows into safety, efficiency, innovation, and trust. Every supplier, buyer, and regulator in the chain depends on a consistent language. Get the label right, underline it with a CAS number, and the rest of the system moves forward with fewer bumps. For a field where precision can make or break a product, that's not just meticulousness—it’s the cost of entry.

1 3-Propanediol 2-ethyl-2-methyl- (8CI)(9CI)