Product Name: 1,2-Propanediol Diacetate
CAS Number: 623-84-7
EC Number: 210-817-6
Synonyms: Propylene Glycol Diacetate, Diacetin Propylene Glycol
Recommended Use: Industrial solvent, coating agent, chemical intermediate
Manufacturer: Supplied by chemical producers, contact info varies by supplier
Emergency Contact: Refer to local emergency response authorities
Restrictions on Use: Not intended for food, medical, or cosmetic use
GHS Classification: Eye irritation, Category 2; Skin irritation, Category 2
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, causes skin irritation
Precautionary Statements: Wash hands thoroughly after handling, wear protective gloves and eye/face protection, avoid release into the environment
Potential Health Effects: Eye, skin, and respiratory irritation on direct contact, may cause coughing or dizziness during high exposure
Environmental Hazards: May cause adverse effects in aquatic ecosystems
Chemical Name: 1,2-Propanediol Diacetate
Chemical Formula: C7H12O4
Concentration: ≥98% pure
Impurities/Additives: Trace moisture, negligible trace solvents (final content influenced by manufacturer standards)
Other Ingredients: No known significant non-hazardous ingredients
Inhalation: Move affected person to fresh air, keep at rest, consult physician if symptoms persist
Skin Contact: Immediately wash area with plenty of water and mild soap, remove contaminated clothing, seek medical attention for irritation
Eye Contact: Rinse thoroughly with water for several minutes, lift eyelids if needed, obtain prompt medical advice
Ingestion: Rinse mouth, avoid inducing vomiting, seek immediate medical attention
Important Symptoms: Redness, burning, irritation, nausea, headache at high exposures
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet can spread burning liquid
Specific Hazards: Vapors may form explosive mixture with air, combustion creates irritating fumes, carbon oxides
Protective Equipment: Firefighters need full protective suit and self-contained breathing apparatus
Advice for Firefighters: Cool tanks with water fog, keep personnel away from downwind smoke, prevent water runoff from entering sewers
Personal Precautions: Shield skin and eyes, ventilate area, avoid inhalation of vapors or contact with liquid
Protective Equipment: Chemical-resistant gloves, safety goggles, suitable protective clothing, adequate respiratory protection for large spills
Environmental Precautions: Keep out of waterways, sewers, natural habitats
Methods for Containment: Absorb spilled material with inert non-flammable material like sand or vermiculite, shovel residue into chemical waste containers
Methods for Cleaning Up: Wipe down surfaces with detergent, dispose of used absorbents per local hazardous waste regulations
Safety Measures: Handle in well-ventilated areas, avoid breathing vapors, minimize splash and aerosol formation
Hygiene Practices: Use gloves, goggles, protective clothing, wash hands after handling, remove contaminated clothing before entering eating areas
Safe Storage Conditions: Store in tightly sealed containers in cool, dry, ventilated locations, keep away from strong oxidizers and acids
Storage Incompatibilities: Avoid strong acids, bases, and oxidizing agents
Special Requirements: Label containers clearly, keep away from food and drink
Occupational Exposure Limits: None established at international level, local regulations may apply
Engineering Controls: Use exhaust ventilation or fume hoods in processing areas
Personal Protective Equipment: Safety goggles, chemical-resistant gloves, lab coat or apron, protective boots as needed
Respiratory Protection: Wear approved respirators if vapors or aerosols are generated above recommended limits
Environmental Controls: Prevent chemical from entering drains, soil, or water bodies
Appearance: Colorless to pale yellow liquid
Odor: Mild ester-like scent
Melting Point: −56°C
Boiling Point: ~213°C
Density: 1.094 g/cm³ at 20°C
Solubility: Miscible with many organic solvents, partially soluble in water
Vapor Pressure: 0.03 mmHg at 25°C
Viscosity: 3.79 mPa·s at 25°C
Flash Point: ~93°C (closed cup)
Auto-ignition Temperature: 410°C
Evaporation Rate: Slower than butyl acetate
pH: Not applicable
Partition Coefficient (log Pow): 0.05
Chemical Stability: Remains stable under normal temperature and storage conditions
Hazardous Reactions: Strong oxidizers trigger violent reactions, mixing with acids or bases can generate heat
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, organic acids by thermal decomposition
Conditions to Avoid: Extreme heat, open flames, poor ventilation
Incompatible Materials: Strong acids, strong bases, oxidizing materials
Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Acute Toxicity: LD50 (oral, rat): around 2000 mg/kg; LD50 (dermal, rabbit): above 4000 mg/kg
Skin Corrosion/Irritation: Moderate irritation possible after prolonged contact
Eye Damage/Irritation: Causes pain and redness
Respiratory Effects: High vapor concentrations may cause coughing, headache, dizziness
Chronic Effects: No known evidence of chronic toxicity in animal studies
Carcinogenicity/Mutagenicity: Studies show no evidence of cancer risk, no mutagenic effects detected
Other Data: Not known to cause sensitization through skin or inhalation
Ecotoxicity: Acute effects possible in aquatic invertebrates and fish at high concentrations
Persistence and Biodegradability: Expected to biodegrade in the environment at moderate rates
Bioaccumulative Potential: Low likelihood due to small log Pow
Mobility in Soil: Moderate, moves with groundwater
Other Adverse Effects: No significant ozone depletion, no contribution to greenhouse effect recorded
Waste Disposal Methods: Dispose of by incineration at licensed chemical waste facility, avoid direct release to drains or surface water
Product Waste: Incinerate or consult local hazardous waste authorities
Contaminated Packaging: Rinse with water, treat as hazardous material, recycle or incinerate as appropriate
Special Precautions: Comply with national and local disposal regulations, prevent product from entering food chains
UN Number: Not regulated for transportation under international standards
Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Environmental Hazards: Avoid contamination of soil and water during movement
Transport in Bulk: Comply with local rules for bulk liquid transfer
Special Precautions: Shield containers from high heat or direct sunlight, prevent tipping or rupture
OSHA Status: Not regulated as hazardous under US OSHA standards
TSCA Inventory: Listed
REACH Status: Registered, not listed as substance of very high concern
SARA 313: No chemical components reportable
California Proposition 65: Not listed
WHMIS (Canada): Not classified as controlled product
Other Local Regulations: Check compliance requirements for region, maintain chemical documentation for workplace safety review
Providing high-quality chemical products and logistics solutions for global trade partners.
