Product Name: 1,2-Propanediol, 3-amino-, (2S)-
Synonyms: (S)-3-Amino-1,2-propanediol, L-Threoninol
CAS Number: 13274-43-4
Recommended Use: Intermediate for chemical synthesis, laboratory reagent
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Use Restrictions: For research, industrial, or professional use only
GHS Classification: Irritant to skin and eyes, possible sensitizer
Hazard Statements: Causes serious eye irritation, may cause skin irritation
Pictograms: Exclamation mark (GHS07)
Label Elements: Warning; Avoid breathing dust; Wash thoroughly after handling
Precautionary Statements: Wear eye/face protection, avoid contact with skin or eyes, use only in a well-ventilated area
Routes of Exposure: Inhalation, skin absorption, eye contact, ingestion
Health Hazards: Acute exposure can lead to respiratory tract irritation, eye damage, skin redness or rash
Chemical Name: 1,2-Propanediol, 3-amino-, (2S)-
Chemical Formula: C3H9NO2
Molecular Weight: 91.11 g/mol
Purity: >98%
Impurities: Minimal, product typically manufactured to high-grade laboratory or pharmaceutical requirements
Other Ingredients: No significant stabilizers, complexing agents, or excipients detected
Inhalation: Remove person to fresh air, keep at rest in a comfortable position, seek medical advice if symptoms develop
Skin Contact: Wash with soap and water for at least 15 minutes, remove contaminated clothing, consult a physician for persistent irritation
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, keep eyelids open, seek professional medical attention if discomfort persists
Ingestion: Rinse mouth, never give anything by mouth to an unconscious person, seek medical attention immediately
Most Important Symptoms: Redness, irritation, burning sensation, coughing
Advice for Medical Responders: Symptomatic care with attention to airway, breathing, and circulation
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Special Hazards: Combustion emits irritating fumes of nitrogen oxides and carbon oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Unusual Fire Hazards: May produce hazardous decomposition products under fire conditions
Firefighting Instructions: Avoid inhaling vapors, contain run-off to avoid environmental contamination
Flash Point: Not determined; expected to be relatively high based on structure
Personal Precautions: Use personal protective equipment, avoid dust formation, provide adequate ventilation
Environmental Precautions: Prevent entry to sewers or public waters, inform authorities if large quantities enter environment
Methods for Cleaning Up: Collect spill with inert absorbent, dispose of in chemical waste container, ventilate area after clean-up
Precautionary Procedures: Wear chemically resistant gloves and safety goggles; avoid skin and eye contact
Decontamination: Wash area thoroughly with water and standard laboratory cleaning agents
Handling: Use in well-ventilated spaces, avoid direct skin and eye contact, do not breathe vapors or dust, wash hands thoroughly after handling
Storage: Store in tightly closed container, protect from direct sunlight, store at 2-8°C, keep away from strong oxidizers or acids
Storage Incompatibilities: Oxidizing agents, acid chlorides, anhydrides
Handling Precautions: Ground and bond containers when transferring material, avoid sources of ignition
Control Parameters: No established occupational exposure limits; minimize exposure as standard chemical hygiene
Engineering Controls: Chemical fume hood, eye wash stations, safety showers
Personal Protective Equipment (PPE): Nitrile or neoprene gloves, safety goggles, lab coat, respiratory protection for high concentrations
Hygiene Measures: Wash hands before breaks or after using the product, keep work clothing separate
Appearance: White to off-white solid or crystalline powder
Odor: Almost odorless or faint amine-like scent
pH: Solutions typically around 7-9
Melting Point: 53–58°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, methanol
Vapor Pressure: Negligible at ambient temperature
Density: ~1.1 g/cm³ at 20°C
Partition Coefficient (log Kow): Not available
Auto-ignition Temperature: Not determined
Evaporation Rate: Not established (low volatility)
Other Properties: Stable under recommended conditions, may darken on exposure to light or air
Chemical Stability: Stable under recommended conditions, avoid prolonged exposure to heat or light
Possibility of Hazardous Reactions: Reacts with strong oxidants, risk of violent reaction with acid chlorides or anhydrides
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, irritant fumes
Incompatible Materials: Strong acids, oxidizing agents, acid chlorides, acid anhydrides
Conditions to Avoid: Moisture, excessive heat, ignition sources
Routes of Exposure: Inhalation, dermal, ocular, oral
Acute Toxicity: Oral LD50 (rat) > 2000 mg/kg, low toxicity expected
Skin Corrosion/Irritation: May cause mild to moderate irritation
Eye Damage/Irritation: Serious eye irritation possible
Respiratory Effects: Irritation of mucous membranes and respiratory tract
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, OSHA
Mutagenicity: Not identified as mutagenic in current literature
Reproductive Toxicity: No data indicating reproductive hazards
Repeated Dose Toxicity: No chronic toxicological effects reported at low exposure levels in animal studies
Human Experience: Eye redness, coughing, skin rash, no severe systemic effects anticipated with routine laboratory use
Ecotoxicity: Insufficient data for specific aquatic species; based on similarity to amino alcohols, low to moderate toxicity expected
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Low, due to high water solubility and rapid degradation
Mobility in Soil: Likely to migrate in water due to hydrophilic character
Other Adverse Effects: Avoid release to environment as a precaution, use adequate containment
Waste Disposal Methods: Dispose in accordance with local, state, national regulations; use approved chemical landfill or incineration
Contaminated Packaging: Empty containers must be handled with same care as chemical; triple rinse before disposal
Special Instructions: Prevent residue in drains or soil, consult waste disposal contractor for proper handling
Regulatory Requirements: Adhere to hazardous waste classification rules if designation applies
UN Number: Not regulated under typical chemical transport rules
Proper Shipping Name: Not classified as hazardous for transport
Hazard Class: Not assigned for land, sea, or air
Packing Group: Not regulated
Marine Pollutant: No
Transport Precautions: Use packaging designed for chemicals, prevent leaks or spills during transit
OSHA: Not specifically regulated
TSCA Status: Listed or exempt
REACH Status: Meets pre-registration or main registration requirements where applicable
SARA Title III: Not a listed substance, no special reporting required
WHMIS Classification (Canada): D2B - toxic material causing other toxic effects (irritant)
EU Classification: Not classified as dangerous based on available data
Other Regulations: Review local, state, national, and international transportation and safety requirements prior to use or distribution
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