MSDS for 1-((1-(S)-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-(2-(1-Hydroxy-1-Methyl)Propanol, 1-(2-(S)-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-((2-(1-Hydroxy-1-Methyl)Ethyl)Phenyl

Identification

Product Name: 1-((1-(S)-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-(2-(1-Hydroxy-1-Methyl)Propanol, 1-(2-(S)-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-((2-(1-Hydroxy-1-Methyl)Ethyl)Phenyl)
Synonyms: Long-chain quinoline derivative with hydroxy-substituted phenyl ethanols
Recommended Use: Laboratory chemical, research applications
Manufacturer: Specialty chemical supplier
Emergency Contact: Safety manager or regional poison control authority, always established at the place where chemistry work happens, vital for urgent response.

Hazard Identification

Physical Hazards: Strongly suspect this compound irritates mucous membranes, and direct contact often causes redness or burning. Inhaling fine particulates tends to make throat or nasal passage sore.
Health Hazards: Quinoline compounds and their derivatives produce headache, dizziness, or are harmful if ingested, so calling for help after exposure is necessary. Skin contact stings and prolonged contact may cause rash or blisters.
Environmental Hazards: Long persistence in aquatic environments raises alarms, especially due to quinoline backbone. Fish, small invertebrates, and even algae may suffer toxic effects if a spill leaches into a stream or pond.

Composition / Information on Ingredients

Chemical Identity: 1-((1-(S)-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-(2-(1-Hydroxy-1-Methyl)Propanol, along with closely related hydroxy quinolinyl phenyl derivatives.
CAS Number: Sourced from supplier, entered into records for traceability.
Concentration: Over 98% for research use, traces of related side-products as identified by QC tests.
Impurities: Trace solvents from synthesis, possible chloride salts under strict tolerance limits.

First Aid Measures

Inhalation: Move to fresh air, keep breathing steady, consult a medical professional if cough, headache, or dizziness lasts. Support conscious breathing, and if any swelling or difficulty appears, seek emergency help.
Skin Contact: Remove contaminated clothing; rinse for several minutes under running water, using mild soap. Persistent rash or blisters deserve medical attention.
Eye Contact: Use eyewash station for at least 15 minutes, gently holding eyelids apart; if vision stays blurred or pain increases, consult a specialist.
Ingestion: Rinse mouth, never induce vomiting, seek physician's help right away with all product information available.
Symptoms: Irritation, allergic-like skin response, headache, fatigue.

Fire-Fighting Measures

Suitable Extinguishing Media: Dry powder, CO2, foam extinguishers control small fires—water spray only in mist form to avoid splash.
Hazardous Combustion Products: Burning could generate hydrochloric acid fumes, carbon oxides, and nitrogen-containing gases.
Special Fire-Fighting Procedures: Structure offers better protection with respirator, full face shield, chemical-resistant gear; move drums if you can without risk.
Unusual Fire or Explosion Hazards: Dust may fuel fire in poorly ventilated areas; strong odors or chlorinated fumes warn of trouble.
Advice for Firefighters: Wear self-contained breathing apparatus and avoid direct contact with smoke or residues.

Accidental Release Measures

Personal Precautions: Evacuate non-essential people, ventilate the area; chemical goggles and gloves are required in all cleanup.
Environmental Precautions: Block spills to keep away from drain or fresh water. Shovel material into tight container for specialized disposal.
Cleanup Methods: Use damp absorbent for powder or solution. Wash surface with water and detergent, dispose residues through regulated waste streams.
Protective Equipment: Wear mask, chemical-proof gloves, and coveralls during cleanup to limit skin and inhalation exposure.
Reporting: Notify safety officer, document scale and area, keep incident record for review.

Handling and Storage

Handling: Work only in ventilated or exhausted spaces, keep chemical far from open flame, food, or incompatible reagents. Pipetting by mouth is never acceptable.
Storage: Locked chemical cabinet, away from moisture and sunlight. Label container with date of receipt, track all removals in a clear log. Segregate from oxidizing, acidic, or basic agents.
Specific Precautions: Use grounded, non-sparking tools; keep containers tightly closed. Rotate stock with oldest first out every time to avoid spoilage.

Exposure Controls and Personal Protection

Engineering Controls: Fume hood or strong local exhaust limits dust and vapors, always run these before opening any bottle.
Personal Protective Equipment: Nitrile gloves, chemical goggles, long-sleeve lab coat; disposable mask or half-face respirator with organic vapor filter in dusty work.
Exposure Limits: No established OSHA PEL or ACGIH TLV, so minimize all unnecessary exposure.
Hygiene Measures: Wash hands and forearms in clean sink after lab work. Never eat or smoke around open product.
Thresholds: Keep air concentrations very low; alert supervisors after any accidental inhalation or skin contact.

Physical and Chemical Properties

Appearance: Pale yellow crystalline powder, sometimes slightly greenish hue under room lighting.
Odor: Sharp, chemical, sometimes fishy due to quinoline; detectable in small amounts if bottle opens.
pH: Not applicable as dry solid, forms mildly alkaline solution in water.
Melting Point: Approximates above 200°C; decomposes with strong fumes near this point.
Boiling Point: Not reliable due to breakdown before actual boiling.
Solubility: Limited solubility in cold water, better in alcohols or DMSO; hazy suspensions clear up in ethanol.
Vapor Pressure: Negligible at room temperature.
Density: Bulk solid falls close to 1.3 g/cm³.
Flash Point: Over 120°C if measured in open cup method.
Partition Coefficient (log Kow): Suggests moderate accumulation in cell membranes, raising handling urgency.

Stability and Reactivity

Chemical Stability: Stable if sealed and dry, but moisture and light slowly trigger decomposition over a few months.
Reactivity: Vigorous reaction possible with oxidizers, acid chlorides, or strong bases.
Hazardous Decomposition: Releases corrosive hydrogen chloride, carbon monoxide and other noxious vapors upon overheating.
Conditions to Avoid: Humidity, high heat, acidic or strongly basic media.
Incompatible Materials: Acid chlorides, peroxides, strong acids. Humid conditions produce sticky cake and chemical breakdown.

Toxicological Information

Acute Effects: Swallowing may cause nausea, vomiting, pain; inhaling dust leads to cough or headache. Skin reddens, stings, and may blister on longer contact. Eyes get watery, painful, especially if particulate grinds under eyelids.
Chronic Effects: Absorption through skin or lungs likely results in long-term liver or kidney risk, especially after frequent low-level exposure. Sensitized individuals develop rash or eczema.
Carcinogenicity: Quinoline-related structures flagged by some animal studies for carcinogenicity; real-life risk rises after long, high-concentration exposures.
Mutagenicity: Laboratory evidence points to DNA interaction with quinoline ring, cautioning pregnant or immunocompromised workers.
Routes of Entry: Inhalation, ingestion, skin and eye absorption—widespread symptoms seen if PPE fails or people do not follow hygiene rules.

Ecological Information

Ecotoxicity: Acute toxicity in small fish, crustaceans, and microorganisms. Leaching or disposal in water causes sudden harm.
Persistence and Degradability: Long-lived in sewage and soil, breakdown lags due to heavy ring structure.
Bioaccumulation: Builds up in aquatic species, potentially entering human food chain where local water is affected.
Mobility in Soil: Moves slowly but persists for seasons in topsoil unless actively removed.
Other Adverse Effects: Microbe populations drop in exposed mud or sediment, hinting at bigger disruptions for local ecosystems.

Disposal Considerations

Waste Treatment Methods: Collect residues in sealable hazardous waste drums; hand over only to permitted disposal provider.
Disposal of Product: Never pour into sink, drain, or landfill—licensed incineration facility handles safe breakdown.
Disposal of Contaminated Packaging: Destroy in accordance with local, regional, national regulations; rinsed containers counted as hazardous unless professionally decontaminated.
Special Precautions: Waste manifest and transfer record essential for all transport or external handoff; label with substance name, risk profile, and generator identity every time.

Transport Information

UN Number: Determined by transporter after classifying with hazardous substance rulebook.
Proper Shipping Name: Name as assigned on shipping manifest or by relevant shipping department.
Transport Hazard Class: Health hazard and environmental warning labels clearly visible on container.
Packing Group: Class II for moderate risk solids (per transporter classification).
Marine Pollutant: Mark as marine pollutant if container exceeds certain mass.
Additional Transport Precautions: Package in double-sealed drum or bottle, use absorbent pad for extra safety in shipment; route transport away from waterways if possible; log all transport in chain-of-custody book.

Regulatory Information

U.S. Regulations: Reference listed hazardous substances under TSCA, SARA Title III, CERCLA guidelines. All OSHA safety practices apply.
EU Regulations: Labeled and tracked according to REACH directive, CLP Regulation assigns hazard pictograms.
Local Regulation: Additional record-keeping as demanded by city or country, plus reporting for any incident above regulatory threshold.
Hazard Symbols: Skull and crossbones, exclamation mark, dead tree/fish icon for environmental hazard, as seen on up-to-date GHS label.
Worker Training: Every employee required to take retraining sessions each year, update SOPs after any incident or major spill, supervisor review for compliance.