Material Safety Data Sheet: α,α-Diphenylpiperidine-1-propanol Hydrochloride

Identification

Product Name: α,α-Diphenylpiperidine-1-propanol hydrochloride
Synonyms: 1-Propanol, α,α-diphenyl-, 1-(1-piperidinyl)-, hydrochloride
Recommended Use: Research and development in biochemical laboratories
Manufacturer: Please refer to the packaging supplier for manufacturer details
Emergency Number: Provide access to poison control centers and local emergency support
CAS Number: 74209-34-4
Address and Contact: Supplier contact information is available through purchase documents or labeling

Hazard Identification

Classification: Acute toxicity (Oral and Dermal), Eye irritation, Specific target organ toxicity (single exposure)
Label Elements: Signal Word: Danger; Pictograms: Skull and crossbones, Exclamation mark
Hazard Statements: Harmful if swallowed; Causes serious eye irritation; Harmful in contact with skin
Precautionary Statements: Wash hands thoroughly after handling; Avoid breathing dust; Wear eye/face protection and gloves; Do not eat, drink or smoke near the substance
Unusual Hazards: May cause respiratory irritation or central nervous system effects

Composition / Information on Ingredients

Chemical Name: α,α-Diphenylpiperidine-1-propanol hydrochloride
Common Name: N/A
CAS Number: 74209-34-4
Percentage: >98% purity for research grade
Impurities: Any unlisted impurities exist at less than 1% and can vary by supplier and batch
Additives: No stabilizers or preservatives reported

First Aid Measures

General Advice: Seek medical attention if symptoms occur or persist
Inhalation: Move to fresh air; keep at rest in a semi-upright position; seek immediate medical attention if symptoms such as dizziness, nausea, or coughing appear
Skin Contact: Wash with plenty of soap and water; remove contaminated clothing; consult a healthcare provider if skin irritation continues
Eye Contact: Thoroughly rinse with plenty of water for several minutes; remove contact lenses if present and easy to do; continue rinsing and seek medical advice as soon as possible
Ingestion: Rinse mouth thoroughly with water; do not induce vomiting; seek immediate medical help
Acute or Delayed Symptoms: Possible headache, nausea, and mucosal irritation; may cause drowsiness or dizziness in severe cases

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or alcohol-resistant foam
Specific Hazards: Thermal decomposition may produce hazardous gases including carbon monoxide, carbon dioxide, hydrochloric acid fumes, and nitrogen oxides
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective clothing
Special Precautions: Avoid breathing smoke or vapors; prevent runoff from fire control from entering water sources or drains
Explosion Data: Not considered an explosion hazard; avoid dust accumulation which can form explosive mixtures with air

Accidental Release Measures

Personal Precautions: Use appropriate personal protective equipment including respirators, gloves, and goggles
Environmental Precautions: Prevent further leakage or spillage if safe to do; avoid discharge into drains, surface water, or soil
Methods for Clean-Up: Carefully sweep up and place in a suitable, clearly labeled container for disposal; ventilate the area and wash spill site; avoid creating airborne dust
Reference to Other Sections: Review sections on Exposure Controls/Personal Protection and Disposal Considerations for guidance on safe clean-up and disposal practices

Handling and Storage

Handling: Work in well-ventilated areas or fume hoods; minimize dust formation; avoid skin and eye contact; wash hands thoroughly after handling; do not eat, drink, or smoke around chemical handling areas
Storage: Store in tightly closed containers in a cool, dry, and well-ventilated place; keep away from incompatible materials such as strong oxidizers, acids, or bases; protect from static discharge and physical damage; store away from food, beverages, and animal feed

Exposure Controls and Personal Protection

Control Parameters: No established occupational exposure limits; monitor for airborne dust
Engineering Controls: Use local exhaust ventilation or other engineering controls to keep airborne concentrations below recommended exposure limits
Personal Protective Equipment: Chemical-resistant gloves, protective clothing, safety goggles, and face shields; approved respirators for procedures generating dust or aerosols
Hygiene Measures: Wash thoroughly after handling; change contaminated clothing promptly; handle according to safety protocols designed to minimize chemical exposure

Physical and Chemical Properties

Appearance: White to off-white solid or crystalline powder
Odor: Odorless or with a faint chemical odor
Odor Threshold: Data not available
pH: Data not available
Melting Point/Freezing Point: Approx. 205°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Data not available
Evaporation Rate: Not applicable
Flammability: Not highly flammable under normal conditions
Vapor Pressure: Negligible at room temperature
Vapor Density: Not determined
Solubility: Soluble in water and common organic solvents
Partition Coefficient: Not measured
Auto-Ignition Temperature: Data not available
Decomposition Temperature: Reports suggest decomposition occurs above 220°C
Viscosity: Not applicable for solids

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Possibility of Hazardous Reactions: No dangerous reactions known under normal use
Conditions to Avoid: Exposure to excessive heat, ignition sources, and moisture
Incompatible Materials: Strong oxidizers, acids, and alkali
Hazardous Decomposition Products: Hydrochloric acid fumes, carbon oxides, nitrogen oxides under fire or extreme heat conditions

Toxicological Information

Routes of Exposure: Ingestion, inhalation, skin and eye contact
Acute Toxicity: Oral LD50 (rat): Data limited, estimated as moderate toxicity based on structural relatives
Chronic Toxicity: Extended exposure can affect central nervous system and possibly liver and kidneys
Symptoms: Irritation to eyes, nose, and throat, gastrointestinal distress, drowsiness, and possible shortness of breath at high exposures
Sensitization: No known reports of skin or respiratory sensitization
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Mutagenicity: Data not available
Reproductive Toxicity: Not enough studies for conclusive statements

Ecological Information

Ecotoxicity: Toxicity to aquatic organisms not thoroughly evaluated; precautionary avoidance recommended
Persistence and Degradability: Not readily biodegradable; may persist in environment
Bioaccumulative Potential: No significant data; likely low bioaccumulation based on molecular properties
Mobility: Tends to retain in soil and sediment; possible limited leaching depending on environmental conditions
Other Adverse Effects: Avoid uncontrolled environmental releases; environmental fate not fully understood

Disposal Considerations

Waste Treatment Methods: Dispose of as hazardous chemical waste; follow local, regional, and national regulations for chemical waste
Product Disposal: Place unused material in clearly labeled hazardous waste containers; consult professional waste disposal services for safe removal
Contaminated Packaging: Empty containers may retain hazardous product residues; handle accordingly; send for proper disposal or recycling according to regulations
Special Precautions: Do not release into sewers, waterways, or natural ecosystems

Transport Information

UN Number: Not assigned for small amounts in research laboratory context
Transport Hazard Class: Not regulated in typical laboratory quantities
Packing Group: Not applicable
Proper Shipping Name: Chemical for laboratory use, not regulated
Environmental Hazards: Not a marine pollutant in containerized form
Special Precautions for Users: Clearly label and package securely; carry documentation for customs or transit authorities where required

Regulatory Information

OSHA: Not specifically listed in hazardous chemical inventories
TSCA: Not listed in the United States Toxic Substances Control Act Inventory
REACH (Europe): Substance not registered
California Proposition 65: Not listed as a carcinogen or reproductive toxicant
WHMIS (Canada): Controlled product; consult provincial requirements
Other International Inventories: Further verification may be required for other jurisdictions; ensure compliance before import, handling, or disposal