Material Safety Data Sheet: (S)-α,α-Diphenyl-3-pyrrolidine acetamide L-Tartaric

Identification

Product Name: (S)-α,α-Diphenyl-3-pyrrolidine acetamide L-Tartaric
Chemical Formula: C22H23NO5
Synonyms: Not widely standardized; commonly referenced in pharmaceutical intermediates
Recommended Use: Research, development, specialty synthesis
Supplier Contact Details: Chemical supply contact information, customer support, and hazard communication address
CAS Number: Available with lot verification from supplier
Emergency Number: 24-hour emergency line for chemical incidents

Hazard Identification

Hazard Pictograms: GHS display symbols—acute toxicity and irritant classifications
Signal Word: Warning
Hazard Statements: Harmful if swallowed; may cause respiratory, skin, and eye irritation
Precautionary Statements: Avoid breathing dust and vapors; wear protective gloves and eye protection; wash hands thoroughly after handling
Potential Acute Effects: Ingestion and inhalation can lead to adverse effects; direct contact causes irritation
Chronic Exposure Risk: Repeated handling can lead to sensitization, persistent respiratory symptoms
Other Hazards: Dusts can form explosive mixtures in air during large-scale handling

Composition / Information on Ingredients

Chemical Identity: (S)-α,α-Diphenyl-3-pyrrolidine acetamide L-Tartaric
Concentration: Pure substance, typical assay >99%
Impurities: Minor process impurities, typically less than 1%, data availability on request
Stabilizers or Additives: None indicated for standard samples
Other Components: Not applicable for this preparation

First Aid Measures

Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do
Skin Contact: Wash affected area thoroughly with soap and water; remove contaminated clothing
Inhalation: Move victim to fresh air; monitor for signs of respiratory distress
Ingestion: Rinse mouth with water; seek medical advice
Special Notes for Healthcare Providers: Symptomatic and supportive care as required; specific antidote information unavailable
Most Important Symptoms: Irritation, burning, coughing, possible allergic reactions on repeat exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Unsuitable Extinguishing Media: Strong water jet may cause spreading; no evidence suggests additional incompatibilities
Fire Hazards: Combustion generates toxic vapors, including CO, NOx
Special Protective Measures: Firefighters should wear self-contained breathing apparatus and full protective clothing
Further Instructions: Approach upwind, contain contaminated runoff

Accidental Release Measures

Personal Precautions: Evacuate nonessential personnel; ventilate area; avoid dust production
Environmental Precautions: Prevent entry into sewers and waterways
Containment Methods: Collect spillage with inert absorbent material and store in closed, labeled containers
Cleanup Procedures: Sweep up with minimal dust generation, use suitable personal protective equipment (PPE)
Disposal: Dispose of as hazardous waste in accordance with local regulations

Handling and Storage

Safe Handling Advice: Use with adequate ventilation; avoid inhaling dust, and contact with skin and eyes
Storage Conditions: Store in tightly closed containers, keep away from direct sunlight, heat, and moisture
Incompatible Materials: Strong oxidizers, strong acids or bases
Hygienic Practices: Wash hands thoroughly before breaks and after work; do not eat, drink, or smoke in the work area
Transfer Precautions: Ground and bond containers during transfer to prevent static discharge

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established; minimize exposure as general rule
Engineering Controls: Work in chemical fume hood or with local exhaust ventilation
Eye Protection: Tight-fitting safety goggles
Skin Protection: Chemical-resistant gloves (nitrile recommended), lab coat
Respiratory Protection: Suitable respiratory device for dust-generating operations or insufficient ventilation
General Hygiene: Change contaminated clothing; ensure washing facilities are available and accessible

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Molecular Weight: 381.43 g/mol
Odor: No significant odor reported
Odor Threshold: Not available
pH: Not determined in aqueous solution
Melting Point: Data varies; inquire for batch-specific details
Boiling Point: Decomposes prior to boiling
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: May pose combustible dust hazard
Vapor Pressure: Negligible at ambient conditions
Solubility: Slightly soluble in water; higher solubility in DMSO and DMF
Partition Coefficient: Data not available
Auto-Ignition Temperature: Not established
Decomposition Temperature: May decompose upon strong heating
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: No hazardous polymerization expected
Conditions to Avoid: High moisture environment, temperatures above ambient storage
Incompatible Materials: Reacts with strong oxidizing agents
Decomposition Products: Burning produces carbon oxides, nitrogen oxides, other toxic gases

Toxicological Information

Acute Toxicity: Limited data; harmful if swallowed
Chronic Toxicity: Not fully characterized for prolonged and repeated exposure
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Sensitization: Possible skin sensitization or allergic response upon repeated handling
Mutagenicity/Carcinogenicity: No conclusive data; handle with care due to lack of long-term studies
Reproductive Toxicity: Not sufficiently tested
Symptoms: Cough, irritation, headache, allergic dermatitis possible with repeated or extended exposure

Ecological Information

Aquatic Toxicity: No specific data; avoid release to waterways due to potential for toxic effects
Persistence and Degradability: Expected to degrade slowly in environment, lacking data on breakdown products
Bioaccumulative Potential: No substantial information; compound structurally falls within bioaccumulative concern range
Mobility in Soil: Limited mobility, but can reach groundwater in cases of spillage
Other Adverse Effects: Minimize exposure outside of controlled systems to reduce risk to surrounding environment

Disposal Considerations

Waste Disposal Methods: Collect and seal in approved hazardous waste containers; dispatch using licensed chemical disposal company
Contaminated Packaging: Handle with same precautions as chemical waste; decontaminate or destroy safely
Environmental Precautions: Do not discharge into drains, soil, or surface water
Regulatory Disposal Requirements: Comply with local, regional, and national hazardous waste regulations; document disposal procedures

Transport Information

UN Number: Assign according to hazard classification, or use “not regulated” if exempt
Transport Hazard Classification: Generally does not fall under hazardous transport for small quantities, but check specifics with logistic provider
Packing Group: As recommended for solid organic substances of similar hazard
Marine Pollutant: Not explicitly listed; avoid bulk transport over water
Special Precautions for Transport: Protect from physical damage, moisture, and heat during transit; ensure clear hazard labeling

Regulatory Information

TSCA Status: Verify inclusion on Toxic Substances Control Act inventory
DSL/NDSL: Compliance check as appropriate for North American shipments
EU REACH: Registration status must be confirmed for import/export
Labeling Requirements: Ensure all chemical identifiers and hazard statements clearly present on container and shipping documents
Additional National/Regional Regulations: Observe all applicable health, safety, and environmental legislation for each jurisdiction in the distribution chain
Workplace Codes: Reference OSHA, WHMIS, or local equivalents for chemical handling